2,309 research outputs found

    Resilient Quantum Electron Microscopy

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    Shot-noise currently limits the resolution of electron cryomicroscopy of beam-sensitive biological specimens. Quantum metrology, despite the potential to surpass this limit, is notoriously sensitive to decoherence. We show that it is possible to significantly neutralize the adverse effect of inelastic electron scattering. This could allow us to study thick specimens of real biological interest.Comment: 21 pages, 7 figures, 2 tables; main conclusions unchange

    Universal Quantum Electron Microscopy: A Small-Scale Quantum Computing Application with Provable Advantage

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    We propose a simple design of a quantum electron microscope that ``queries'' a beam-sensitive phase object, such as a biological specimen, as part of quantum computation. Lower quantum query complexity, not the time complexity, of a quantum algorithm means less specimen damage, which translates to more data extracted from the specimen. Hence small-scale quantum computing offers provable quantum advantage in this context. A possible application of the proposed microscope is the Grover search for a true structure, out of a set of candidate structures.Comment: 11 pages, 3 figure

    Industrial Networks between China and the Countries of the Asia-Pacific Region

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    This paper investigates the changes in the structures of industrial networks that have occurred in the Asia-Pacific region in line with the rapid growth of the Chinese economy. Analyses using international input-output tables revealed that during the 1990s, there was a significant increase in the dependence of Asian countries’ manufacturing industries, such as textiles and electronics, on China’s industries, though industries in Japan and the United States remain important as the main suppliers of industries in Asian countries

    Regulation of bone by the adaptive immune system in arthritis

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    Studies on the immune regulation of osteoclasts in rheumatoid arthritis have promoted the new research field of 'osteoimmunology', which investigates the interplay between the skeletal and immune systems at the molecular level. Accumulating evidence lends support to the theory that bone destruction associated with rheumatoid arthritis is caused by the enhanced activity of osteoclasts, resulting from the activation of a unique helper T cell subset, 'Th17 cells'. Understanding the interaction between osteoclasts and the adaptive immune system in rheumatoid arthritis and the molecular mechanisms of Th17 development will lead to the development of potentially effective therapeutic strategies
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