34 research outputs found

    Economic and environmental impacts of changes in culling parity of cows and diet composition in Japanese beef cow–calf production systems

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    The effects of changes in culling parity of cows and diet composition on economic and environmental outputs in Japanese beef cow–calf production systems were deterministically analyzed using a herd model simulation. The model simulated the annualized net revenue as an economic indicator and the overall environmental index derived from a life cycle assessment (LCA) as an environmental indicator. Biological factors (survivability, growth, reproduction, and feed requirements) and economic factors (returns from sales of live calves and cows’ carcasses and production costs) were included in the model. The model also included modified feed formulation methods, allowing us to analyze the effect of reductions in environmental loads caused by the change in diet compositions. The results of the present study indicated that later culling was economically and environmentally optimal under the current production system, which suggested that the selection of economically optimal culling parity of cows could result in environmentally optimization of the beef cow–calf production system. The difference in feed composition derived from the difference in feed formulation methods did not affect the determination of optimal culling parity, whereas the use of modified feed formulation methods could reduce environmental loads at a higher rate than that of economic benefits. However, the reduction rate of the environmental impact was much higher in the case of selection of the optimal culling parity than in the case of use of modified feed formulation methods, which stressed the importance of choosing the optimal culling parity of cows both from the economic and environmental points of view

    Prenatal Torsion of Radial Polydactyly: A Gangrenous Mass at the Base of the Thumb

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    A patient was born with a mass at the base of the thumb approximately 1.5 cm in diameter on the radial side of the fingers. The mass had globular swelling filled with hemorrhagic fluid and was dark red. X-rays and histology of the excised specimen suggested the diagnosis of gangrene and torsion of polydactyly. Prenatal torsion of polydactyly is not a common occurrence; moreover, prenatal torsion of polydactyly has only been found in ulnar polydactyly. Our case is a novel case of radial polydactyly that was gangrenous at birth owing to prenatal torsion. Diagnosing such a mass at the base of the thumb is important

    The potential hazard of a non-slip element balloon causing distal longitudinal stent deformation: the first clinical experience and in vitro assessment

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    Background: A new complication, longitudinal stent deformation (LSD), is increasingly reported withrecent intracoronary stent designs. There have been experiences of unusual cases of distal LSD causedby entrapment of a Lacrosse® non-slip element (NSE) balloon (Goodman Co., Ltd., Nagoya, Japan),which has three flexible nylon elements to prevent slippage. Accordingly, the aim of this study is to reportthe clinical experience of distal LSD caused by the NSE in the documented center and to investigate theincidence and mechanisms involved.Methods: Coronary intervention cases were retrospectively reviewed using the NSE balloon in hospitalbetween May 2014 and June 2017. In bench testing, distal LSD was reproduced in a silicon tube modelto identify its mechanism.Results: A total of 95 patients with 107 lesions underwent coronary interventions with NSE. Of these,72 lesions (12 de-novo lesions and 60 in-stent restenosis) were treated using in-stent dilatation. Twodistal LSD cases occurred, representing an incidence of 2.78% (2/72) among all procedures; 16.7%(2/12) of the de-novo lesions developed LSD. In vitro experimentation allowed indentification of themechanisms involved and bailout strategies.Conclusions: This is the first study to evaluate NSE balloon catheter entrapment complicated by distalLSD in which reconstruction of the deformed stent and retrieval of the NSE could be achieved successfully.There is a potential hazard for distal LSD during post-dilatation using the NSE balloon due to itsstructural characteristics. Careful assessment is needed to prevent this complication

    Haplotypes of PADI4 susceptible to rheumatoid arthritis are also associated with ulcerative colitis in the Japanese population.

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    Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn\u27s disease (CD), is a chronic inflammatory disorder characterized by intractable inflammation specific to the gastrointestinal tract. The precise etiology of IBD remains unknown. Recently, haplotypes of peptidylarginine deiminase type 4 (PADI4) have been identified as the rheumatoid arthritis (RA)-susceptible gene. PADI4 is located at 1p36, which is one of chromosomal loci susceptible for IBD. Then, we examined whether haplotypes and diplotypes of PADI4 are associated with IBD in the Japanese population. We studied haplotypes of PADI4 in 114 patients with UC, 83 patients with CD, and 200 gender-matched healthy controls by PCR-restriction fragment length polymorphism. Frequencies and distributions of haplotypes and diplotypes were compared statistically between patients and controls by logistic regression analysis. The frequency of haplotype 1 was significantly decreased in patients with UC, compared to that in controls (P=0.037; odds ratio (OR)=0.702). In contrast, the frequency of haplotype 2 in patients with UC was significantly higher than that in controls (P=0.003; OR=1.722). Moreover, of a total of 114 patients with UC, 15 (13.2%) had a diplotype homozygous for haplotype 2, the frequency being significantly higher than in controls (9/200, 4.5%; P=0.008, OR=3.215). Our results indicate that haplotype 1 of PADI4 is associated with non-susceptibility to UC, whereas haplotype 2 is susceptible to UC. Thus, it is likely that PADI4 is one of genetic determinants of UC in the Japanese population

    Spatially resolved measurement of helium atom emission line spectrum in scrape-off layer of Heliotron J by near-infrared Stokes spectropolarimetry

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    1視線の観測のみで核融合プラズマ中のヘリウム近赤外輝線の発光分布を推定. 京都大学プレスリリース. 2022-09-26.For plasma spectroscopy, Stokes spectropolarimetry is used as a method to spatially invert the viewing-chord-integrated spectrum on the basis of the correspondence between the given magnetic field profile along the viewing chord and the Zeeman effect appearing on the spectrum. Its application to fusion-related toroidal plasmas is, however, limited owing to the low spatial resolution as a result of the difficulty in distinguishing between the Zeeman and Doppler effects. To resolve this issue, we increased the relative magnitude of the Zeeman effect by observing a near-infrared emission line on the basis of the greater wavelength dependence of the Zeeman effect than of the Doppler effect. By utilizing the increased Zeeman effect, we are able to invert the measured spectrum with a high spatial resolution by Monte Carlo particle transport simulation and by reproducing the measured spectra with the semiempirical adjustment of the recycling condition at the first walls. The inversion result revealed that when the momentum exchange collisions of atoms are negligible, the velocity distribution of core-fueling atoms is mainly determined by the initial distribution at the time of recycling. The inversion result was compared with that obtained using a two-point emission model used in previous studies. The latter approximately reflects the parameters of atoms near the emissivity peak

    Polymorphisms of PTPN11 coding SHP-2 as biomarkers for ulcerative colitis susceptibility in the Japanese population.

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    OBJECTIVE: To identify genetic determinants of inflammatory bowel disease (IBD), we examined an association between polymorphisms of both the programmed cell death 1 gene (PDCD1) and the src homology 2 domain-containing tyrosine phosphatase 2 gene (PTPN11) and susceptibility to IBD. METHODS: Study subjects comprised 114 patients with ulcerative colitis (UC), 83 patients with Crohn\u27s disease, and 200 healthy control subjects. Five single nucleotide polymorphisms (SNPs) in PDCD1 and PTPN11 were detected by polymerase chain reaction restriction fragment length polymorphism. Subsequently, haplotypes composed of the two SNPs in PTPN11 were constructed. RESULTS: The frequencies of the Hap 1 haplotype and its homozygous Hap 1/Hap 1 diplotype of PTPN11 were significantly increased in UC patients compared to control subjects (P = 0.011 and P = 0.030, respectively). While no association was found for PDCD1 for UC or CD and none for PTPN11 for CD. CONCLUSION: PTPN11 is a genetic determinant for the pathogenesis of UC, and haplotyping of PTPN11 may be useful as a genetic biomarker to identify high-risk individuals susceptible to UC

    ムキョクセイ ヨウバイチュウ ニ オケル ポリブタジエニル リチウム リビング アニオンサ ノ カイゴウタイ ノ ダイナミクス ト コウゾウ

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    京都大学0048新制・課程博士博士(工学)甲第13302号工博第2834号新制||工||1416(附属図書館)UT51-2007-H667京都大学大学院工学研究科分子工学専攻(主査)教授 渡辺 宏, 教授 堀井 文敬, 教授 金谷 利治学位規則第4条第1項該当Doctor of EngineeringKyoto UniversityDA

    Cluster polarization behavior of a MIMO system: Measurement, modeling and statistical validation of the correlation of its channel parameters

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    This paper presents clusterwise polarization characteristics based on an estimated MIMO channel of a small urban macrocell at 4.5 GHz. Polarization path gain, cross-polarization ratio, and co-polarization ratio characteristics as influenced by channel parameters such as delay, azimuth and elevation angle of arrival were investigated. Hypothesis testing was used as a verification of the results. This statistical verification clarifies the independence of polarization characteristics from an azimuth angle of arrival, whereas some correlation was found between the cross-polarization ratio and the elevation angle of arrival. The results also confirmed a log-normal cross-polarization ratio
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