2,153 research outputs found
Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode
The inner ear derives from a patch of ectoderm defined by expression of the transcription factor Pax2. We recently showed that this Pax2^+ ectoderm gives rise not only to the otic placode but also to the surrounding cranial epidermis, and that Wnt signaling mediates this placode-epidermis fate decision. We now present evidence for reciprocal interactions between the Wnt and Notch signaling pathways during inner ear induction. Activation of Notch1 in Pax2+ ectoderm expands the placodal epithelium at the expense of cranial epidermis, whereas loss of Notch1 leads to a reduction in the size of the otic placode. We show that Wnt signaling positively regulates Notch pathway genes such as Jag1, Notch1 and Hes1, and we have used transgenic Wnt reporter mice to show that Notch signaling can modulate the canonical Wnt pathway. Gain- and loss-of-function mutations in the Notch and Wnt pathways reveal that some aspects of otic placode development - such as Pax8 expression and the morphological thickening of the placode - can be regulated independently by either Notch or Wnt signals. Our results suggest that Wnt signaling specifies the size of the otic placode in two ways, by directly upregulating a subset of otic genes, and by positively regulating components of the Notch signaling pathway, which then act to augment Wnt signaling
Irregular conformal blocks, with an application to the fifth and fourth Painlev\'e equations
We develop the theory of irregular conformal blocks of the Virasoro algebra.
In previous studies, expansions of irregular conformal blocks at regular
singular points were obtained as degeneration limits of regular conformal
blocks; however, such expansions at irregular singular points were not clearly
understood. This is because precise definitions of irregular vertex operators
had not been provided previously. In this paper, we present precise definitions
of irregular vertex operators of two types and we prove that one of our vertex
operators exists uniquely. Then, we define irregular conformal blocks with at
most two irregular singular points as expectation values of given irregular
vertex operators. Our definitions provide an understanding of expansions of
irregular conformal blocks and enable us to obtain expansions at irregular
singular points.
As an application, we propose conjectural formulas of series expansions of
the tau functions of the fifth and fourth Painlev\'e equations, using
expansions of irregular conformal blocks at an irregular singular point.Comment: 26 page
Sub-parsec-scale Accleration of the Radio Jet in the Powerful Radio Galaxy NGC 6251
In order to investigate the genesis of powerful radio jet, we have mapped the
central 10 pc region of the nearby radio galaxy NGC 6251 with a 0.2 pc
resolution using Very Long Baseline Interferometer (VLBI) at two radio
frequencies, 5 GHz and 15 GHz, we have found the sub-parsec-scale counterjet
for the first time in this radio galaxy. This discovery allows us to
investigate the jet acceleration based on the relativistic beaming model.Comment: 7 pages with 7 figures. To appear in PASJ, 52, No. 5, Oct. 25, 200
What Controls the Star Formation in Luminous Starburst Mergers ?
In order to understand what controls the star formation process in luminous
starburst mergers (e.g., NGC 6240, Arp 220, and so on), we investigate
observational properties of two samples of high-luminosity starburst galaxies
mapped in CO(=1--0) independently using both the Owens Valley Radio
Observatory (Scoville et al. 1991) and the IRAM interferometer (Downes &
Solomon 1998). We find that the surface density of far-infrared luminosity,
(FIR), is proportional linearly to the H surface mass density,
(H), for the two samples; (FIR) (H) with a correlation coefficient of 0.96. It is
often considered that (FIR) provides a good measure of the star
formation rate per unit area, (SFR). It is also known that molecular
gas is dominated in circumnuclear regions in the luminous starburst mergers;
i.e., (gas) (H). Therefore, the above relationship
suggests a star formation law; (SFR) (gas). We suggest
that this star formation law favors the gravitational instability scenario
rather than the cloud-cloud collision one.Comment: 14 pages, 2 figures. The Astrophysical Journal (Letters), in pres
An Origin of the Huge Far-Infrared Luminosity of Starburst Mergers
Recently Taniguchi and Ohyama found that the higher CO to CO
integrated intensity ratios at a transition =1--0, CO)CO) , in a sample of starburst merging
galaxies such as Arp 220 are mainly attributed to the depression of CO
emission with respect to CO. Investigating the same sample of galaxies
analyzed by Taniguchi & Ohyama, we find that there is a tight, almost linear
correlation between the dust mass and CO luminosity. This implies that
dust grains are also depressed in the high- starburst mergers, leading to
the higher dust temperature () in them because of the relative
increase in the radiation density. Nevertheless, the average dust mass () of the high- starburst mergers is higher significantly than that of
non-high galaxies. This is naturally understood because the galaxy mergers
could accumulate a lot of dust grains from their progenitor galaxies together
with supply of dust grains formed newly in the star forming regions. Since
(FIR) given the dust emissivity law, , the increases in both and
explain well why the starburst mergers are so bright in the FIR. We discuss
that the superwind activity plays an important role in destroying dust grains
as well as dense gas clouds in the central region of mergers.Comment: 10 pages (aaspp4.sty), 3 postscript figures (embedded). Accepted for
publication in Astrophysical Journal Letter
Detection of Polarized Broad Emission in the Seyfert 2 Galaxy Mrk 573
We report the discovery of the scattered emission from a hidden broad-line
region (BLR) in a Seyfert 2 galaxy, Mrk 573, based on our recent
spectropolarimetric observation performed at the Subaru Telescope. This object
has been regarded as a type 2 AGN without a hidden BLR by the previous
observations. However, our high quality spectrum of the polarized flux of Mrk
573 shows prominent broad (~3000 km/s) H_alpha emission, broad weak H_beta
emission, and subtle Fe II multiplet emission. Our new detection of these
indications for the presence of the hidden BLR in the nucleus of Mrk 573 is
thought to be owing to the high signal-to-noise ratio of our data, but the
possibility of a time variation of the scattered BLR emission is also
mentioned. Some diagnostic quantities such as the IRAS color, the radio power,
and the line ratio of the emission from the narrow-line region of Mrk 573 are
consistent with the distributions of such quantities of type 2 AGNs with a
hidden BLR. Mrk 573 is thought to be an object whose level of the AGN activity
is the weakest among the type 2 AGNs with a hidden BLR. In terms of the
systematic differences between the type 2 AGNs with and without a hidden BLR,
we briefly comment on an interesting Seyfert 2 galaxy, Mrk 266SW, which may
possess a hidden BLR but has been treated as a type 2 AGNs without a hidden
BLR.Comment: 9 pages including 6 figures, to appear in The Astronomical Journa
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