2,306 research outputs found
Sketch-based Influence Maximization and Computation: Scaling up with Guarantees
Propagation of contagion through networks is a fundamental process. It is
used to model the spread of information, influence, or a viral infection.
Diffusion patterns can be specified by a probabilistic model, such as
Independent Cascade (IC), or captured by a set of representative traces.
  Basic computational problems in the study of diffusion are influence queries
(determining the potency of a specified seed set of nodes) and Influence
Maximization (identifying the most influential seed set of a given size).
Answering each influence query involves many edge traversals, and does not
scale when there are many queries on very large graphs. The gold standard for
Influence Maximization is the greedy algorithm, which iteratively adds to the
seed set a node maximizing the marginal gain in influence. Greedy has a
guaranteed approximation ratio of at least (1-1/e) and actually produces a
sequence of nodes, with each prefix having approximation guarantee with respect
to the same-size optimum. Since Greedy does not scale well beyond a few million
edges, for larger inputs one must currently use either heuristics or
alternative algorithms designed for a pre-specified small seed set size.
  We develop a novel sketch-based design for influence computation. Our greedy
Sketch-based Influence Maximization (SKIM) algorithm scales to graphs with
billions of edges, with one to two orders of magnitude speedup over the best
greedy methods. It still has a guaranteed approximation ratio, and in practice
its quality nearly matches that of exact greedy. We also present influence
oracles, which use linear-time preprocessing to generate a small sketch for
each node, allowing the influence of any seed set to be quickly answered from
the sketches of its nodes.Comment: 10 pages, 5 figures. Appeared at the 23rd Conference on Information
  and Knowledge Management (CIKM 2014) in Shanghai, Chin
Gibbs free energy difference between the undercooled liquid and the beta-phase of a Ti-Cr alloy
The heat of fusion and the specific heats of the solid and liquid have been experimentally determined for a Ti60Cr40 alloy. The data are used to evaluate the Gibbs free energy difference, DELTA-G, between the liquid and the beta-phase as a function of temperature to verify a reported spontaneous vitrification (SV) of the beta-phase in Ti-Cr alloys. The results show that SV of an undistorted beta-phase in the Ti60Cr40 alloy at 873 K is not feasible because DELTA-G is positive at the temperature. However, DELTA-G may become negative with additional excess free energy to the beta-phase in the form of defects
Gibbs free-energy difference between the glass and crystalline phases of a Ni-Zr alloy
The heats of eutectic melting and devitrification, and the specific heats of the crystalline, glass, and liquid phases have been measured for a Ni24Zr76 alloy. The data are used to calculate the Gibbs free-energy difference, DeltaGAC, between the real glass and the crystal on an assumption that the liquid-glass transition is second order. The result shows that DeltaGAC continuously increases as the temperature decreases in contrast to the ideal glass case where DeltaGAC is assumed to be independent of temperature
Polymorphisms in the 5′-UTR of PTEN and other gene polymorphisms in normal Japanese individuals
Polymorphisms are distributed differently in populations, including those of regions, ethnic groups, and diseased patients. In order to investigate variation in nucleotide sequences in normal individuals, we isolated genomic DNA from the blood of healthy Japanese individuals  and sequenced the 5'-untranslated region (5'- UTR) of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) gene and the gene promoter, intron, and exon nucleotides of p53, p14ARF, murine double minute 2 (MDM2), and the β2- and β3-adrenoceptor (-AR). We found polymorphisms in these regions, including a deletion at positions –465 to –463 and a substitution at position –404 in PTEN and a substitution at position  –4924 in p14ARF, in normal individuals. Individuals with or without the PTEN polymorphism harbored a different distribution of polymorphisms, including simultaneous alterations in nucleotides of p53, MDM2, and β3-AR, and also harbored some polymorphic nucleotides located in the same set of associatively altered nucleotides. Our results show that multiple nucleotides, including the PTEN nucleotides, are altered in normal Japanese individuals and provide useful information for genotyping studies in individuals and populations.Полиморфизмы широко распространены в популяциях, включая регионы, этнические группы и больных пациентов. Для исследования изменчивости нуклеотидных последовательностей у нормальных индивидов , мы выделили геномную ДНК из крови здоровых японцев и секвенировали 5′-нетранслируемый участок (5′-UTR) гена фосфатазы и гомолога тензина (PTEN), промоторные последовательности, интроны и экзоны генов p53 и p14ARF, ингибитора супрессора опухолевого роста p53 (MDM2) и   генов β2- and β3-адренореце (-AR). Мы обнаружили полиморфизм по этим участкам, включая делецию в положении с −465 to −463 и замену в положении −404 в PTEN и замену  в положении −4924 в p14ARF у нормальных индивидов. Индивиды с и без полиморфизма PTEN имели различное распределение полиморфизма, включая одновременные  изменения в нуклеотидах p53, MDM2 и 3-AR, и также имели полиморфные нуклеотиды, локализованные в том же наборе совместно измененных нуклеотидов.  Наши результаты показывают, что множественные нуклеотиды, включая нуклеотиды PTEN, изменены у нормальных японских индивидов и дают полезную информацию  для исследований по генотипированию индивидов и популяций
Rat white adipocytes activate p85/p110 PI3K and induce PM GLUT4 in response to adrenoceptor agonists or aluminum fluoride
Adipocyte responses to adrenergic and ß-adrenoceptor(-AR) (adrenoceptor) regulation are not sufficiently understood, and information helpful for elucidating the adrenoceptor-responsive machinery is insufficient. Here we show by using immunoprecipitated kinase analysis with a phosphatidylinositol 3-kinase (PI3K) p85 antibody that PI3K activation was induced by treatment with 10 or 100 µM norepinephrine (NE) for 15 min or with 10 mM aluminum fluoride (AF, a guanosine triphosphate (GTP)-binding (G) protein activator) for 20 min in white adipocytes (rat epididymal adipocytes) and that treatment with pertussis toxin (PTX, a G-protein inactivator) inhibited PI3K activation induced by the 20-min treatment with AF in the cells. In addition, western blot analysis revealed that glucose transporter 4 (GLUT4) level in the adipocyte plasma membrane (PM) fraction was increased by treatment with 10 µM NE, 100 µM dobutamine (DOB, a ß1-AR agonist), or 0.1 µM CL316243 (CL, a ß3-AR agonist) for 30 min or with 10 mM AF for 20 min. NE or AF treatment triggered 2-deoxyglucose (2-DG) uptake into adipocytes under the above conditions. Our results advance the understanding of responses to adrenoceptor regulation in white adipocytes and provide possible clues for clarifying the machinery involved in adrenergic and ß-AR responses in the cells
Holistic Influence Maximization: Combining Scalability and Efficiency with Opinion-Aware Models
The steady growth of graph data from social networks has resulted in
wide-spread research in finding solutions to the influence maximization
problem. In this paper, we propose a holistic solution to the influence
maximization (IM) problem. (1) We introduce an opinion-cum-interaction (OI)
model that closely mirrors the real-world scenarios. Under the OI model, we
introduce a novel problem of Maximizing the Effective Opinion (MEO) of
influenced users. We prove that the MEO problem is NP-hard and cannot be
approximated within a constant ratio unless P=NP. (2) We propose a heuristic
algorithm OSIM to efficiently solve the MEO problem. To better explain the OSIM
heuristic, we first introduce EaSyIM - the opinion-oblivious version of OSIM, a
scalable algorithm capable of running within practical compute times on
commodity hardware. In addition to serving as a fundamental building block for
OSIM, EaSyIM is capable of addressing the scalability aspect - memory
consumption and running time, of the IM problem as well.
  Empirically, our algorithms are capable of maintaining the deviation in the
spread always within 5% of the best known methods in the literature. In
addition, our experiments show that both OSIM and EaSyIM are effective,
efficient, scalable and significantly enhance the ability to analyze real
datasets.Comment: ACM SIGMOD Conference 2016, 18 pages, 29 figure
Specific volumes of the Zr41.2Ti13.8Cu12.5Ni10.0Be22.5 alloy in the liquid, glass, and crystalline states
The specific volumes of the Zr41.2Ti13.8CU12.5Ni10.0Be2.25 alloy as a function of temperature, T, are determined by employing an image digitizing technique and numerical calculation methods applied to the electrostatically levitated spherical alloy. The linear fitting of the volumes of the alloy in the liquid, V-l, glass, V-g, and crystalline V-c, states in the temperature ranges shown in parentheses are V-l(T) = 0.1583 + 8.877 x 10(-6)T(cm^(3)/g) (700-1300 K); V-g(T) = 0.1603 + 5.528 x 10^(-6)T (400-550 K); V-c(T) = 0.1583 + 6.211 x 10(-6)T(400-850 K). The average volume thermal expansion coefficients within the temperature ranges are determined to be 5.32, 3.39, and 3.83 x 10^(-5) (1/K) for the liquid, glass, and crystalline states, respectively
Noncontact technique for measuring surface tension and viscosity of molten materials using high temperature electrostatic levitation
A new, noncontact technique is described which entails simultaneous measurements of the surface tension and the dynamic viscosity of molten materials. In this technique, four steps were performed to achieve the results: (1) a small sample of material was levitated and melted in a high vacuum using a high temperature electrostatic levitator, (2) the resonant oscillation of the drop was induced by applying a low level ac electric field pulse at the drop of resonance frequency, (3) the transient signals which followed the pulses were recorded, and (4) both the surface tension and the viscosity were extracted from the signal. The validity of this technique was demonstrated using a molten tin and a zirconium sample. In zirconium, the measurements could be extended to undercooled states by as much as 300 K. This technique may be used for both molten metallic alloys and semiconductors
On the Power of Tree-Depth for Fully Polynomial FPT Algorithms
There are many classical problems in P whose time complexities have not been improved over the past decades.
Recent studies of "Hardness in P" have revealed that, for several of such problems, the current fastest algorithm is the best possible under some complexity assumptions.
To bypass this difficulty, the concept of "FPT inside P" has been introduced.
For a problem with the current best time complexity O(n^c), the goal is to design an algorithm running in k^{O(1)}n^{c\u27} time for a parameter k and a constant c\u27<c.
In this paper, we investigate the complexity of graph problems in P parameterized by tree-depth, a graph parameter related to tree-width.
We show that a simple divide-and-conquer method can solve many graph problems, including
Weighted Matching, Negative Cycle Detection, Minimum Weight Cycle, Replacement Paths, and 2-hop Cover,
in O(td m) time or O(td (m+nlog n)) time, where td is the tree-depth of the input graph.
Because any graph of tree-width tw has tree-depth at most (tw+1)log_2 n, our algorithms also run in O(tw mlog n) time or O(tw (m+nlog n)log n) time.
These results match or improve the previous best algorithms parameterized by tree-width.
Especially, we solve an open problem of fully polynomial FPT algorithm for Weighted Matching parameterized by tree-width posed by Fomin et al. (SODA 2017)
Ferromagnetism at 300 K in spin-coated films of Co doped anatase and rutile TiO2
Thin films of Ti1-xCoxO2 (x=0 and 0.03) have been prepared on sapphire
substrates by spin-on technique starting from metalorganic precursors. When
heat treated in air at 550 and 700 C respectively, these films present pure
anatase and rutile structures as shown both by X-ray diffraction and Raman
spectroscopy. Optical absorption indicate a high degree of transparency in the
visible region. Such films show a very small magnetic moment at 300 K. However,
when the anatase and the rutile films are annealed in a vacuum of 1x10-5 Torr
at 500 oC and 600 oC respectively, the magnetic moment, at 300 K, is strongly
enhanced reaching 0.36 B/Co for the anatase sample and 0.68
B/Co for the rutile one. The ferromagnetic Curie temperature of these
samples is above 350 K.Comment: 31 july 200
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