An antenna-pointing mechanism for the ETS-6 K-band Single Access (KSA) antenna

Both the design philosophy for the Antenna Pointing Mechanism (APM) to be used for the K-band Single Access (KSA) antenna system and experimental results of the APM Engineering Model (EM) tests are described. The KSA antenna system will be flown on the Engineering Test Satellite 6 (ETS-6)

New Lymphology Combined with Lymphatic Physiology, Innate Immunology, and Oncology

ArticleJournal of Blood & Lymph. 4(2):126 (2014)journal articl

Current topics of physiology and pharmacology in the lymphatic system

ArticlePharmacology & therapeutics. 2005;105(2):165-188journal articl

Pivotal roles of shear stress in the microenvironmental changes that occur within sentinel lymph nodes

A sentinel lymph node (SLN) is the first lymph node that receives drainage from a primary tumor. According to their physiological and biomechanical characteristics, we hypothesized that SLN contains lymphatic endothelial cells (LEC) that are constantly loaded with high levels of shear stress, which might contribute to the production of a suitable environment for micrometastasis within them. To test this hypothesis, we investigated the effects of shear stress stimulation on the expression of adhesion molecules on human LEC isolated from the lymph vessels nearest the SLN of breast cancers, and on the release of ATP from human LEC. The study clarified that the shear stress stimulation produced a significant increase of ICAM-1 expression at protein and mRNA levels in human LEC. Next, we examined whether the shear stress-mediated increase of ICAM-1 expression accelerates the attachment of carcinoma cells to human LEC. Finally, in in vivo experiments, we evaluated whether exogenous ATP facilitates the expression of carcinoma cell-ligated adhesion molecules in rat SLN. In conclusion, shear stress stimulation induces ICAM-1 expression on human LEC by activating cell surface F1/FO ATP synthase, which might contribute to the development of a premetastatic environment within SLN. (Cancer Sci 2012; 103: 12451252)ArticleCANCER SCIENCE. 103(7):1245-1252 (2012)journal articl

Ultrasonication-induced Amyloid Fibril Formation of β2-Microglobulin

This research was originally published in the Journal of Biological Chemistry. Yumiko Ohhashi, Miho Kihara, Hironobu Naiki and Yuji Goto. Ultrasonication-induced Amyloid Fibril Formation of β2-Microglobulin. J. Biol. Chem. 2005; 280, 32843-32848. © the American Society for Biochemistry and Molecular Biolog

Effects of exercise intensity, posture, pressure on the back and ambient temperature on palmar sweating responses due to handgrip exercises in humans

ArticleAutonomic neuroscience: basic & clinical. 2005;118(1-2):125-134journal articl