Preference Reasons for Recreational Areas Which Belongs to the Local Administrations

The purpose of this study was to determine the effective factors of people choosing outdoor recreation areas, which is belonging to local government in Elazıg Province Center, for feel comfortable in social, cultural and physiological aspects where they can evaluate their free time and benefit from different purposes according to different variables.The sample group of the study consisted of 232 persons, 106 male and 126 female, selected randomly using recreational areas of local governance in Elazıg province center. The data were obtained by participation preference factors for use of recreation area survey which consist 24 questions and 5 sub-dimensions that developed by Gümüs H. and Alay Özgül S. (2017) with face to face survey application method.The data obtained from the study were analyzed using the SPSS 22 packet program. The normality test has been done so that analyzes can be done correctly. According to this, Kruskal-wallis was used in multiple groups in the analysis of data which not normal distribution and Mann Whitney-u Test was applied to determine the group which the difference occurred. In the analysis of normal distribution data, anova in multiple groups and independent samples t test in binary groups were applied. Significance level was accepted as p0, 05).It was determined that, for participants who married and with children, it is effective that there is playground for children in the recreational areas, the individuals who are good and very good health status are influenced by the sport diversity, activity and personnel situation in choosing these areas, private vehicle ownership is not that important for choosing these areas

Clinical Study Effect of Ice Bag Application to Femoral Region on Pain in Patients Undergoing Percutaneous Coronary Intervention

Aims. The aim of this study is to determine the pain reduction effectiveness of ice bag applications to the femoral region in patients undergoing percutaneous coronary intervention. Material and Methods. A randomized controlled trial with repeated measures and two-group design. The study was completed with a total of 104 patients who met the inclusion criteria: 52 each in the experimental group and the control group. The pain experienced by the patients was evaluated before and during removal and again while the nurse applied pressure on the catheter site after removal. The NRS scores were identified as NRS1, NRS2, and NRS3 for the three assessment, respectively. Results. The NRS1 score was similar between the two groups. It increased at the 2nd measurement, and a statistically significant difference was determined between the two groups (4.0 (3.0-4.0) in the experimental group and 6.0 (4.0-7.0) in the control group) ( < 0.001). Conclusions. The results of the study revealed that ice bag application to femoral region was effective in reducing pain induced by femoral catheter removal in patients undergoing percutaneous coronary intervention. Local ice bag application may therefore be recommended as a nursing intervention for pain control in such cases

The relationship between Chlamydophila pneumoniae IgG titer and coronary atherosclerosis

Background: The role of Chlamydophila pneumoniae (CP) in the progression of atherosclerosis is controversial. Also no sufficient angiographic study is available about the impact of CP infection on severity and intensity of coronary atherosclerosis. We investigated the relation between CP IgG antibody titers and severity and intensity of coronary atherosclerosis Methods: The study population consisted of 516 consecutive patients who underwent a coronary angiography. The group included 353 patients who had coronary artery disease; a control group included 163 subjects with angiographically proven normal coronary arteries. Chlamydophila pneumoniae IgG antibody titers were measured by an enzyme immunoassay method in all patients. Gensini scores and extent scores were used to evaluate the angiographic extent and severity of atherosclerosis. Results: The mean value of IgG antibody titer was 44.3 &#177; 28.8 IU/mL in the patients and 39.8 &#177; 27.4 IU/mL in the control group (p = 0.14). There was no statistically significant correlation between the Gensini scores, extent scores and CP IgG titers (Gensini score: r = +0.103, p = 0.07, extent score: r = +0.110, p = 0.31). When we grouped the patients as high (> 50 IU/mL) and low (< 50 IU/mL) IgG antibody titers, the number of diseased coronary arteries was higher in patients with high IgG antibody titers (respectively: 2.6 &#177; 1.1 vs. 2.2 &#177; 0.8, p = 0.01). While the Gensini score was significantly higher in patients with high IgG antibody titers (7.5 &#177; 4.0 vs. 6.17 &#177; 4.0, p = 0.01), the extent score did not change with IgG titers (29.8 &#177; 15.9 vs. 25.8 &#177; 15.4, p = 0.08). Conclusions: In our study, we investigated the relation between CP infection and coronary atherosclerosis and found that CP IgG antibody titers are associated with the severity of coronary stenosis at higher antibody levels. However, there is no association between CP antibody titers and clinical presentation of coronary artery disease. We suggest that CP has limited effect on coronary atherosclerosis. (Cardiol J 2008; 15: 245-251

Razine 3-nitrotirozina kod neurotoksičnosti izazvane diklorvosom

The aim of this study was to evaluate dichlorvos toxicity in terms of nitro-oxidative stress by determining 3-nitrotyrosine (3-NT) levels in the fore, mid, and hindbrain regions in acutely exposed rats. Male Sprague- Dawley rats were randomly allocated to three groups of eight. Group 1 was administered a single intraperitoneal dichlorvos dose of 1.8 mg kg-1 (0.1xLD50) and group 2 a dose of 9 mg kg-1 (0.5xLD50). The control group received 0.5 mL saline solution via the same route. 3-NT and tyrosine (TYR) levels were measured using high performance liquid chromatography with a photodiode array detector (HPLC-PDA) and expressed as a ratio of 3-NT to TYR. The 3-NT/1000 TYR ratios increased significantly in the fore-, mid- and hindbrains of the exposed groups compared to control (p<0.01). In the forebrain, the increase was also significant between the treated groups. Our study has confirmed that acute exposure to dichlorvos leads to nitro-oxidative stress in the brain and that 3-NT may play a role in the mechanism of dichlorvos neurotoxicity.Cilj je ovog ispitivanja bio ocijeniti neurotoksičnost diklorvosa kroz nitrooksidativni stres mjerenjem razina 3-nitrotirozina (3-NT) u prednjem, središnjem i stražnjem režnju mozga akutno izloženih mužjaka štakora Sprague-Dawley, koji su u tu svrhu nasumce bili podijeljeni u tri skupine po osam životinja. Skupina 1 primila je jednokratnu intraperitonealnu dozu diklorvosa od 1,8 mg kg-1 (0,1xLD50), a skupina 2 dozu od 9 mg kg-1 (0,5xLD50). Kontrolna je skupina primila 0,5 mL fiziološke otopine, također intraperitonealno. Razine 3-NT-a i tirozina (TIR) izmjerene su tekućinskim kromatografom visoke djelotvornosti s detektorom s nizom dioda (HPLC-PDA) te su izražene kao omjer 3-NT:TIR. Omjeri 3-NT/1000 TIR značajno su se povećali u svim režnjevima izloženih skupina (1 i 2) u odnosu na kontrolnu skupinu (p<0,01). Povećanje je također bilo značajno u prednjem režnju skupine 2 u odnosu na skupinu 1, ali nije bilo značajne razlike između izloženih skupina u ostalim režnjevima. Naše je istraživanje potvrdilo da akutna izloženost diklorvosu dovodi do nitrooksidativnog stresa u mozgu te da 3-NT sudjeluje u mehanizmu neurotoksičnosti diklorvosa

Improved arterial stiffness in mitral stenosis after successful percutaneous balloon valvuloplasty

Background: Rheumatic mitral stenosis (MS) is still a common disease in developing countries with high morbidity and mortality rates. The purpose of the study was to evaluate arterial stiffness in severe MS before and after percutaneous mitral balloon valvuloplasty (PMBV). Methods: Thirty patients with MS in sinus rhythm requiring PMBV and 20 age-gender matched healthy volunteers. The analyze of pulse wave velocities (PWV) were performed using of the carotid artery at the femoral by PWV technique on patients at baseline and a week after PMBV. Results: The values of PWV were significantly decreased after successful PMBW in MS patients. Mitral mean gradients and systolic pulmonary artery pressures (sPAP) both on echocardiography and catheterization also had a significant decrease after PMBW. The mitral valve areas were significantly increased after PMBW. There was a highly significant negative correlation between mitral valve areas and PWV values. A highly significant positive correlation was seen between mitral mean gradient on catheterization and PWV (r = 0.830, p < 0.001). There was also a significant correlation between sPAP on catheterization and PWV values (r = 0.639, p < 0.001). Echocardiographic mitral mean gradients and PWV were highly positive correlated with each other (r = 0.841, p < 0.001). The sPAP on echocardiography had also a highly positive correlation with PWV (r = 0.681, p < 0.001). Conclusions: Mitral stenosis is a cause of impaired arterial stiffness and after the enlargened mitral valve area arterial stiffness improved in patients with MS

Comparison between rest technetium-99m-tetrofosmin and rest-redistribution thallium-201 SPECT in stable patients with healed myocardial infarction

Resting Tc-99m-tetrofosmin (TF) uptake was compared with thallium (Tl-201) rest-redistribution (R-RD) uptake in patients with previous myocardial infarction (MI) and significant coronary artery disease (CAD) to assess the ability of TF to detect viable myocardium. We studied 30 patients (21 males and nine females, mean age 53.9 +/- 12.5 years) with prior MI and left ventricular dysfunction who had been referred for coronary revascularization procedures. Myocardial single photon emission computed tomography (SPECT) images were obtained 1 h after injection of 750 MBq of TF. Within I week of the TT study, R-RD Tl-201 SPECT imaging was performed after injection of 111 MBq of Tl-201. Quantitative analysis was performed in 21 segments. Viability was defined as the presence of tracer uptake greater than 50% of the peak activity on baseline studies or after reversibility. There was significant correlation between the quantitative regional R-RD Tl-201 activity and the resting TF activity (r=0.88, P<0.001). Quantitative analysis showed that the uptake of the two tracers was comparable in normal segments as well as in segments with fixed Tl-201 defects. In contrast, in segments with reversible Tl-201 defects, TF uptake was significantly greater than resting Tl-201 uptake, but lower than R-RD Tl-201 uptake. There were 52 segments (47% of the severely reduced segments on TF images) that showed no viability with TF, but were viable on the redistribution Tl-201 studies. We conclude that quantitative resting TF SPECT underestimates the presence of viable myocardium compared with R-RD Tl-201 imaging on the basis of using 50% of the peak activity as the viability threshold. ((C) 2001 Lippincott Williams & Wilkins)

Severe aortic regurgitation after repair of ruptured sinus of Valsalva aneurysm: The role of Transesophageal Echocardiography

We report a 27-year-old woman who presented with worsening exertional. dyspnea and palpitation. Transthoracic echocardiography showed ventricular septal defect, with left-to-right shunting and mild aortic regurgitation detected. Cardiac catheterization was performed that revealed sinus of Valsalva aneurysm with rupture into the right ventricle. Transesophageal echocardiography (TEE) confirmed a rupture of sinus of Valsalva aneurysm and ventricular septal defect. The patient underwent elective surgical repair of the ruptured sinus and intraoperative TEE demonstrated severe aortic regurgitation after repair and mechanical prosthetic valve was implanted. This case illustrates that TEE frequently establishes the diagnosis and provides more information concerning additional cardiac lesions in a patient with ruptured sinus of Valsalva aneurysm. Aortic regurgitation should be evaluated after repair of rupture of sinus of Valsalva by TEE