Observation of Dynamic Interactions between Fundamental and Second-Harmonic Modes in a High-Power Sub-Terahertz Gyrotron Operating in Regimes of Soft and Hard Self-Excitation

Dynamic mode interaction between fundamental and second-harmonic modes has been observed in high-power sub-terahertz gyrotrons [T. Notake et al., Phys. Rev. Lett. 103, 225002 (2009); T. Saito et al. Phys. Plasmas 19, 063106 (2012)]. Interaction takes place between a parasitic fundamental or firstharmonic (FH) mode and an operating second-harmonic (SH) mode, as well as among SH modes. In particular, nonlinear excitation of the parasitic FH mode in the hard self-excitation regime with assistance of a SH mode in the soft self-excitation regime was clearly observed. Moreover, both cases of stable twomode oscillation and oscillation of the FH mode only were observed. These observations and theoretical analyses of the dynamic behavior of the mode interaction verify the nonlinear hard self-excitation of the FH mode

A novel type of binding specificity to phospholipids for rat mannose-binding proteins isolated from serum and liver

AbstractMannose-binding protein (MBP) belongs to the collectin subgroup of C-type lectins with specificity for mannose and N-acetylglucosamine sugars. We investigated whether rat MBPs isolated from serum (S-MBP) and liver (L-MBP) interact with phospholipids using antibody against each MBP. Both S- and L-MBPs bound to phosphatidylinositol coated onto microtiter wells in a concentration- and a Ca2+-dependent manner. L-MBP also bound to phosphatidylglycerol and weakly to phosphatidylserine. MBPs interacted with liposomes composed of these lipids. S- and L-MBPs bound to phosphatidylinositol 4-monophosphate. L-MBP also bound to cardiolipin. These results provide evidence for a novel type of ligand binding specificity for MBPs, and raise the possibility that phospholipids are ligands for collectins

チョメイナ カンガイ ハツイク オ シメシタ カンケッカンシュ ノ 1レイ

Giant hemangiomas of the liver with the diameter of more then 10 cm are likely to grow rapidly with bleeding in tumor and concur a terrible complication such as heavy bleeding caused by tumor rupture. We experienced a case of giant hemangioma of the liver with a pronounced extrahepatic growth. A 33-year-old woman consulted a doctor because of common cold and was pointed out having hepatomegaly. She was admitted to the hospital for further examination. Abdominal ultrasonography showed a heterogenous high echoic tumor with even surface lying ventral to the gallbladder from the margin inferior hepatis. Abdominal CT scan showed a low density tumor which growed from S4, 5 and 6 of the liver to extrahepatic area. The tumor was confirmed to show low intensity on T1-weighted images and remarkable high intensity on T2-weighted images on a magneticresonance imaging scan and had strong contract effect from the edge by a contract medium. It showed cotton wool like appearance on an angiography. It was diagnosed as hemangioma of the liver and a partial hepatic resection was conducted. The resected tumor was rubiginous, spongy, 11×5.5×7.5 cm in size and 660g in weight. Histopathologically, it was diagnosed as cavernous hemangioma

State- and water repellency-controllable molecular glass of pillar[5]arenes with fluoroalkyl groups by guest vapors

Molecular glasses are low-molecular-weight organic compounds that are stable in the amorphous state at room temperature. Herein, we report a state- and water repellency-controllable molecular glass by n-alkane guest vapors. We observed that a macrocyclic host compound pillar[5]arene with the C₂F₅ fluoroalkyl groups changes from the crystalline to the amorphous state (molecular glass) by heating above its melting point and then cooling to room temperature. The pillar[5]arene molecular glass shows reversible transitions between amorphous and crystalline states by uptake and release of the n-alkane guest vapors, respectively. Furthermore, the n-alkane guest vapor-induced reversible changes in the water contact angle were also observed: water contact angles increased and then reverted back to the original state by the uptake and release of the n-alkane guest vapors, respectively, along with the changes in the chemical structure and roughness on the surface of the molecular glass. The water repellency of the molecular glass could be controlled by tuning the uptake ratio of the n-alkane guest vapor

Cell jamming, stratification and p63 expression in cultivated human corneal epithelial cell sheets

Corneal limbal epithelial stem cell transplantation using cultivated human corneal epithelial cell sheets has been used successfully to treat limbal stem cell deficiencies. Here we report an investigation into the quality of cultivated human corneal epithelial cell sheets using time-lapse imaging of the cell culture process every 20 minutes over 14 days to ascertain the level of cell jamming, a phenomenon in which cells become smaller, more rounded and less actively expansive. In parallel, we also assessed the expression of p63, an important corneal epithelial stem cell marker. The occurrence of cell jamming was variable and transient, but was invariably associated with a thickening and stratification of the cell sheet. p63 was present in all expanding cell sheets in the first 9 days of culture, but it’s presence did not always correlate with stratification of the cell sheet. Nor did p63 expression necessarily persist in stratified cell sheets. An assessment of cell jamming, therefore, can shed significant light on the quality and regenerative potential of cultivated human corneal epithelial cell sheets

Notch Filter in 70 GHz Range for Microwave Plasma Diagnostics

A notch filter for the rejection of stray light from gigahertz range heating sources was developed to protect a vulnerable microwave plasma diagnostic system. As one of the applications, we consider the installation of the notch filter into the receiver of a collective Thomson scattering diagnostic in the Large Helical Device. Experimental observations indicate that two types of notch filters are required for main and spurious mode rejection; they have very narrow, steep shapes to avoid disturbing the diagnostic signal. On the basis of numerically simulated results, notch filters were fabricated, and their performance was evaluated. An attenuation level of 35 dB at 74.746 GHz with a 3 dB bandwidth of 0.49 GHz is achieved by two pairs of resonator cavities. This attenuation is acceptable in our study