Primary production in the Southern Baltic in 1985 and 1986 compared with long-term mean seasonal variation

On the basis of long-term investigations, the course of seasonal variations of mean daily primary production and mean chlorophyll-a concentration in the Southern Baltic waters are presented. The mean annual primary production of the Gdańsk Deep, Bornholm Deep and the Gotland Deep amounted to 124.4 gC m-2, 88.8 gC m-2 and 107.2 gC m-2, respectively. The primary production of the Southern Baltic in 1986 was higher than in 1985, and higher than the long-term mean value. The mean annual production for the Southern Baltic in 1986 amounted to 130 gC m-2. On the basis of long-term observations of primary production and chlorophyll-a of the Southern Baltic, certain upward trends in phytoplankton production were observed

How much of the invader’s genetic variability can slip between our fingers? A case study of secondary dispersal of Poa annua on King George Island (Antarctica)

We studied an invasion of Poa annua on King George Island (Maritime Antarctic). The remoteness of this location, its geographic isolation, and its limited human traffic provided an opportunity to trace the history of an invasion of the species. Poa annua was recorded for the first time at H. Arctowski Polish Antarctic Station in the austral summer of 1985/6. In 2008/9, the species was observed in a new locality at the Ecology Glacier Forefield (1.5 km from “Arctowski”). We used AFLP to analyze the genetic differences among three populations of P. annua: the two mentioned above (Station and Forefield) and the putative origin of the introduction, Warsaw (Poland). There was 38% genetic variance among the populations. Pairwise ФPT was 0.498 between the Forefield and Warsaw populations and 0.283 between Warsaw and Station. There were 15 unique bands in the Warsaw population (frequency from 6% to 100%) and one in the Station/Forefield populations (which appears in all analyzed individuals from both populations). The Δ(K) parameter indicated two groups of samples: Warsaw/Station and Forefield. As indicated by Fu’s Fs statistics and an analysis of mismatch distribution, the Forefield population underwent a bottleneck and/or founder effect. The Forefield population was likely introduced by secondary dispersal from the Station population

The Ursinus Weekly, October 25, 1973

Fraternities select homecoming candidates; Students will vote for favorites today • Ursinus will make record books with giant banana split • Chemistry department gets $3000 grant • Longer hours suggested for noisy Myrin library • Volunteer service program begins work; Ken-Crest Center will be first effort • Editorial: Minority student speaks out on biological overpopulation • Faculty portrait: Mrs. Mary Anne Clausen • The Big Game • Alumni corner • Letter to the editor: Tradition and the individual • Lord Caradon, U.N. Representative, speaks on “obligation of optimism” • Shaw-Bernard art exhibit opens today • Placement office helpful for job-hunting seniors • Bearettes sweep south and extend wins to nine • Harriers return to winning ways • Sing wins tournament • Soccer team’s record now stands at 3-3-1 • Ursinus Bears win first game of the seasonhttps://digitalcommons.ursinus.edu/weekly/1003/thumbnail.jp

Co-expression network of neural-differentiation genes shows specific pattern in schizophrenia

Background: Schizophrenia is a neurodevelopmental disorder with genetic and environmental factors contributing to its pathogenesis, although the mechanism is unknown due to the difficulties in accessing diseased tissue during human neurodevelopment. The aim of this study was to find neuronal differentiation genes disrupted in schizophrenia and to evaluate those genes in post-mortem brain tissues from schizophrenia cases and controls. Methods: We analyzed differentially expressed genes (DEG), copy number variation (CNV) and differential methylation in human induced pluripotent stem cells (hiPSC) derived from fibroblasts from one control and one schizophrenia patient and further differentiated into neuron (NPC). Expression of the DEG were analyzed with microarrays of post-mortem brain tissue (frontal cortex) cohort of 29 schizophrenia cases and 30 controls. A Weighted Gene Co-expression Network Analysis (WGCNA) using the DEG was used to detect clusters of co-expressed genes that werenon-conserved between adult cases and controls brain samples. Results: We identified methylation alterations potentially involved with neuronal differentiation in schizophrenia, which displayed an over-representation of genes related to chromatin remodeling complex (adjP = 0.04). We found 228 DEG associated with neuronal differentiation. These genes were involved with metabolic processes, signal transduction, nervous system development, regulation of neurogenesis and neuronal differentiation. Between adult brain samples from cases and controls there were 233 DEG, with only four genes overlapping with the 228 DEG, probably because we compared single cell to tissue bulks and more importantly, the cells were at different stages of development. The comparison of the co-expressed network of the 228 genes in adult brain samples between cases and controls revealed a less conserved module enriched for genes associated with oxidative stress and negative regulation of cell differentiation. Conclusion: This study supports the relevance of using cellular approaches to dissect molecular aspects of neurogenesis with impact in the schizophrenic brain. We showed that, although generated by different approaches, both sets of DEG associated to schizophrenia were involved with neocortical development. The results add to the hypothesis that critical metabolic changes may be occurring during early neurodevelopment influencing faulty development of the brain and potentially contributing to further vulnerability to the illness.We thank the patients, doctors and nurses involved with sample collection and the Stanley Medical Research Institute. This research was supported by either Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq #17/2008) and Fundação Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ). MM (CNPq 304429/2014-7), ACT (FAPESP 2014/00041-1), LL (CAPES 10682/13-9) HV (CAPES) and BP (PPSUS 137270) were supported by their fellowshipsinfo:eu-repo/semantics/publishedVersio

Pharmacological activities of aminoflavones

Aminoflavones belong to a group of flavonoids, compounds commonly found in nature. Their pharmacological and biochemical effects include cytotoxic, antioxidant and antitumor properties. The studies have shown that complexes of aminoflavons with metal ions can be potential drugs and seem to be promising in the treatment of ovarian cancer, breast cancer, lung adenocarcinoma and melanoma. In addition aminoflavones have a lower cytotoxic activity towards healthy cells than another compounds. In the view of their wide pharmacological and biological actions, they seem to have great therapeutic potential

Can disorganisation of semantic memory account for the abnormalities of thought in schizophrenia - a controlled experimental study

Peer reviewe

Long-term changes in primary production and chlorophyll concentrations in the Southern Baltic

The paper presents results of long-term investigations on primary production and chlorophyll a concentrations at two stations in the Southern Baltic (in the Gdańsk Deep and in the Bornholm Deep). The data show increasing trends in the annual primary production and mean chlorophyll a contents. A mean increase in the annual primary production within the recent years is estimated at 1-2% per year