Social and emotional resources inventory: further development of a comprehensive self-report measure of protective factors, The

2019 Spring.Includes bibliographical references.Historically, childhood trauma has been associated with a variety of negative life outcomes including poor emotional adjustment in adulthood, low educational and professional attainment, and all manner of psychopathology. However, more recent research has noted that the majority of individuals with histories of childhood trauma adapt quite successfully to adulthood and live happy and productive lives. Researchers now recognize that the presence of certain protective environmental and personal factors can improve how children cope with obstacles presented by histories of trauma. By identifying these factors, researchers can help clinicians, social justice advocates and others take a pro-active approach, as opposed to a reactive approach, to reducing the negative effects of childhood trauma. There currently exists no highly comprehensive measure of protective factors. This study aimed to finalize the Social Emotional Resources Inventory (SERI) - a comprehensive measure of protective factors - by revising the SERI where necessary and providing previously lacking estimates of convergent and discriminant evidence. The final SERI was considered to be a good fit for the data. The final SERI consists of 55 items, grouped into 14 factors, which may be hierarchically grouped into second and third-order factors if necessary. The results of this SERI administration demonstrated acceptable test-retest reliability and convergent/discriminant evidence across most sub-scales

Tribute to John Pickering

John left word that he did not want a lot of eulogies, so there is much I could say about him that I do not because I honor his request

Derivatives of Natural Organocatalytic Cofactors and Artificial Organocatalytic Cofactors as Catalysts in Enzymes

Catalytically active non‐metal cofactors in enzymes carry out a variety of different reactions. The efforts to develop derivatives of naturally occurring cofactors such as flavins or pyridoxal phosphate and the advances to design new, non‐natural cofactors are reviewed here. We report the status quo for enzymes harboring organocatalysts as derivatives of natural cofactors or as artificial ones and their application in the asymmetric synthesis of various compounds

Nosocomial Infections among Pediatric Patients with Neoplastic Diseases

Background. Pediatric patients with neoplastic diseases are more likely to develop nosocomial infections (NIs). NIs may prolong their hospital stay, and increase morbidity and mortality. Objectives. The objectives of this study were to determine: (1) the incidence of NIs, (2) sites of NIs, (3) causal organisms, and (4) outcomes of NIs among pediatric patients with neoplastic diseases. Methods. This study was a prospective cohort study of pediatric patients with neoplastic diseases who were admitted to the Chiang Mai University Hospital, Thailand. Results. A total of 707 pediatric patients with neoplastic diseases were admitted. Forty-six episodes of NIs in 30 patients were reported (6.5 NIs/100 admission episodes and 7 NIs/1000 days of hospitalization). Patients with acute lymphoblastic leukemia had the highest number of NIs (41.3%). The most common causal organisms were gram-negative bacteria (47.1%). Patients who had undergone invasive procedures were more likely to develop NIs than those who had not (P < .05). The mortality rate of patients with NIs was 19.6%. Conclusion. Pediatric patients with neoplastic diseases are more likely to develop NIs after having undergone invasive procedures. Pediatricians should be aware of this and strictly follow infection control guidelines in order to reduce morbidity and mortality rates related to NIs