Chiral primary amino alcohol organobase catalyst for the asymmetric Diels-Alder reaction of anthrones with maleimides

Simple chiral TES-amino alcohol organocatalysts containing a bulkysilyl [triethylsilyl: TES] group on oxygen atom at γ-position were designed andsynthesized as new organocatalysts for the enantioselective Diels-Alder (DA) reactionof anthrones with maleimides to produce chiral hydroanthracene DA adducts (up to99% yield with up to 94% ee)

Chiral primary amino alcohol organobase catalyst for the asymmetric Diels-Alder reaction of anthrones with maleimides

application/pdfSimple chiral TES-amino alcohol organocatalysts containing a bulky silyl [triethylsilyl: TES] group on oxygen atom at γ-position were designed and synthesized as new organocatalysts for the enantioselective Diels-Alder (DA) reaction of anthrones with maleimides to produce chiral hydroanthracene DA adducts (up to 99% yield with up to 94% ee)