6 research outputs found
Optical effects of exposing intact human lenses to ultraviolet radiation and visible light
<p>Abstract</p> <p>Background</p> <p>The human lens is continuously exposed to high levels of light. Ultraviolet radiation is believed to play a causative role in the development of cataract. In vivo, however, the lens is mainly exposed to visible light and the ageing lens absorbs a great part of the short wavelength region of incoming visible light. The aim of the present study was to examine the optical effects on human lenses of short wavelength visible light and ultraviolet radiation.</p> <p>Methods</p> <p>Naturally aged human donor lenses were irradiated with UVA (355 nm), violet (400 and 405 nm) and green (532 nm) lasers. The effect of irradiation was evaluated qualitatively by photography and quantitatively by measuring the direct transmission before and after irradiation. Furthermore, the effect of pulsed and continuous laser systems was compared as was the effect of short, intermediate and prolonged exposures.</p> <p>Results</p> <p>Irradiation with high intensity lasers caused scattering lesions in the human lenses. These effects were more likely to be seen when using pulsed lasers because of the high pulse intensity. Prolonged irradiation with UVA led to photodarkening whereas no detrimental effects were observed after irradiation with visible light.</p> <p>Conclusions</p> <p>Irradiation with visible light does not seem to be harmful to the human lens except if the lens is exposed to laser irradiances that are high enough to warrant thermal protein denaturation that is more readily seen using pulsed laser systems.</p
Cloud cover and horizontal plane eye damaging solar UV exposures
The spectral UV and the cloud cover were measured at intervals of 5 min with an integrated cloud and spectral UV measurement system at a sub-tropical Southern Hemisphere site for a 6-month period and solar zenith angle (SZA) range of 4.7 degrees to approximately 80 degrees. The solar UV spectra were recorded between 280 and 400 nm in 0.5 nm increments and weighted with the action spectra for photokeratitis and cataracts in order to investigate the effect of cloud cover on the horizontal plane biologically damaging UV irradiances for cataracts (UVBEcat) and photokeratitis (UVBEpker). Eighty five percent of the recorded spectra produced a measured irradiance to a cloud free irradiance ratio of 0.6 and higher while 76% produced a ratio of 0.8 and higher. Empirical non-linear expressions as a function of SZA have been developed for all sky conditions to allow the evaluation of the biologically damaging UV irradiances for photokeratitis and cataracts from a knowledge of the unweighted UV irradiances