58 research outputs found
Logic Ciucuits Using Solution-processed Single-walled Carbon Nanotue Transistors
This letter reports on the realization of logic circuits employing
solution-processed networks of single-walled carbon nanotubes. We constructed
basic logic gates (inverter, NAND and NOR) with n- and p-type field-effect
transistors fabricated by solution-based chemical doping. Complementary
metal-oxide-semiconductor inverters exhibited voltage gains of up to 20, which
illustrates the great potential of carbon nanotube networks for printable
flexible electronics.Comment: 12 PAGES, 3 FIGURE
Critical Nature of the Size Exponent of Polymers
On the basis of the thermodynamic theory of the excluded volume effects, we
show that the size exponent varies abruptly, depending on the change of the
segment concentration. For linear polymers, the exponent changes
discontinuously from for the isolated system () in good
solvents to in the finite concentration (), while
for branched polymers having , the corresponding exponent varies
from () to ().Comment: 10 pages, 10 figure
The Molecular Structure of cis-4-Aza-A-homo-tetrahydro-a-santonin and trans-4- Aza- A- homo- tetrahydro-a-santonin Related to the Lactam Rule
Stereochemistry of the titled compounds was determined by X-ray structure analysis. The seven-membered lactam rings of both compounds are in a quasi-chair conformation which agrees
with the lactam rule. The mean values of the C-NH-CO-C torsion angles are -6 ° and +5°, respectively, and these values
also agree with Klyne\u27s hypothesis
The Molecular Structure of Six-Membered Lactams Related to the Lactam Rule
Stereoehemistry of isodihydrolumisantoninlaetam (2) was determined by means of X-ray analysis and CD. The six-membered laetam ring of 2 and D-glueono-1,5-lactam (3) is in halfehair eonformation in agreement with the lactam rule
Extensive genomic diversity and selective conservation of virulence determinants in enterohemorrhagic Escherichia coli strains of O157 and non O157 serotypes
Background: Enterohemorrhagic Escherichia coli (EHEC) O157 causes severe food-borne illness in humans. The chromosome of O157 consists of 4.1 Mb backbone sequences shared by benign E. coli K-12, and 1.4 Mb O157-specific sequences encoding many virulence determinants, such as Shiga toxin genes (stx genes) and the locus of enterocyte effacement (LEE). Non-O157 EHECs belonging to distinct clonal lineages from O157 also cause similar illness in humans. According to the "parallel" evolution model, they have independently acquired the major virulence determinants, the stx genes and LEE. However, the genomic differences between O157 and non-O157 EHECs have not yet been systematically analyzed. Results: Using microarray and whole genome PCR scanning analyses, we performed a whole genome comparison of 20 EHEC strains of O26, O111, and O103 serotypes with O157. In non-O157 EHEC strains, although genome sizes were similar with or rather larger than O157 and the backbone regions were well conserved, O157-specific regions were very poorly conserved. Around only 20% of the O157- specific genes were fully conserved in each non-O157 serotype. However, the non-O157 EHECs contained a significant number of virulence genes that are found on prophages and plasmids in O157, and also multiple prophages similar to, but significantly divergent from, those in O157. Conclusion: Although O157 and non-O157 EHECs have independently acquired a huge amount of serotype- or strain-specific genes by lateral gene transfer, they share an unexpectedly large number of virulence genes. Independent infections of similar but distinct bacteriophages carrying these virulence determinants are deeply involved in the evolution of O157 and non-O157 EHECs
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