6 research outputs found
Effects of African Mistletoe Extract on Blood Pressure in Spontaneously Hypertensive Rats
Influence of Loranthus micranthus against STZ-Induced Neurobehavioral Deficits in Diabetic Rats
The use of lysosomal enzymuria in the early detection and monitoring of the progression of diabetic nephropathy
Possibilidades terapĂȘuticas e risco toxicolĂłgico de Jatropha gossypiifolia L.: uma revisĂŁo narrativa Therapeutic possibilities and toxicological risk of Jatropha gossypiifolia L.: a narrative review
A espĂ©cie Jatropha gossypiifolia L. (Euphorbiaceae), popularmente conhecida como piĂŁo-roxo, entre tantos outros nomes, Ă© um bom exemplo do tĂȘnue limiar que separa o efeito terapĂȘutico do tĂłxico. Apesar de ser classicamente conhecida como planta tĂłxica possui usos na medicina popular. Alguns desses efeitos tĂȘm sido comprovados em estudos experimentais, como os de antimicrobiano, antineoplĂĄsico, cicatrizante e hipotensor, sendo possivelmente explicados pela presença de substĂąncias como alcalĂłides, terpenĂłides, flavonĂłides, lignanas e taninos. Esta revisĂŁo aborda aspectos importantes, com ĂȘnfase na toxicidade crĂŽnica dessa espĂ©cie, de modo a servir de fonte de informação aos interessados em avaliar a relação risco/benefĂcio do uso terapĂȘutico de Jatropha gossypiifolia L.<br>The species Jatropha gossypiifolia L. (Euphorbiaceae), popularly known as bellyache bush, among several other names, is an important example of the tenuous threshold that separates the therapeutic from the toxic effect. Although traditionally known as a toxic plant, it has been used in folk medicine. Some of its effects have been proved by experimental studies as antimicrobial, antineoplastic, healing and hypotensive, likely explained by the presence of substances such as alkaloids, terpenoids, flavonoids, lignans and tannins. This review deals with important aspects, focusing on the chronic toxicity of this species, in order to serve as an information source for those interested in evaluating the risk-benefit ratio of the therapeutic use of Jatropha gossypiifolia L