DIFFICULTY IN DIAGNOSTICS TO VERIFY CROHN’S DISEASE IN CHILDREN. CLINICAL CASE STUDY

Diagnostics of Crohn’s disease, especially in children, presents a big challenge, given the low prevalence rate of this disease, polymorphism of the clinical manifestation and insufficient alertness of primary pediatricians relative to this pathology. As a result, untimely diagnostics, and, therefore, inadequate treatment, the disease takes an unfavourable turn, complications develop resulting in disabilities of little patients. The provided material and described clinical case study help physicians to identify Crohn’s disease in due time and refer the patient to a specialised medical establishment for additional examination and determining treatment tactics.Key words: inflammatory bowel disease, Crohn’s disease, diagnostics, children. (Pediatric Pharmacology. – 2010; 7(2):115-122

DIFFICULTY IN DIAGNOSTICS TO VERIFY CROHN’S DISEASE IN CHILDREN. CLINICAL CASE STUDY

Diagnostics of Crohn’s disease, especially in children, presents a big challenge, given the low prevalence rate of this disease, polymorphism of the clinical manifestation and insufficient alertness of primary pediatricians relative to this pathology. As a result, untimely diagnostics, and, therefore, inadequate treatment, the disease takes an unfavourable turn, complications develop resulting in disabilities of little patients. The provided material and described clinical case study help physicians to identify Crohn’s disease in due time and refer the patient to a specialised medical establishment for additional examination and determining treatment tactics.Key words: inflammatory bowel disease, Crohn’s disease, diagnostics, children. (Pediatric Pharmacology. – 2010; 7(2):115-122

Effciency of HIV-infected patients detection in neurological hospitals of large industrial center

<p><em>Aim of the study: </em>to evaluate the effciency of detection for HIV-infection in patients of neurological departments of Saratov. <em>Materials and methods. </em>We retrospectively analyzed 25 250 medical histories of patients hospitalized into neurological departments of Saratov hospitals between January 2007 and April 2012. <em>Results. </em>Blood samples of 2010 patients (7,96 %) were tested for the presence of HIV-antibodies. 37 patients were HIV-positive (1,84 % of examined patients and 0,15 % of the total number of patients). <em>Conclusion. </em>Increasing popularity and variety of clinical manifestations of HIV-infection requires the expansion of neurological patients whom serum test for antibodies against HIV is needed.</p&gt

СЛОЖНОСТЬ ДИАГНОСТИЧЕСКОГО ПОИСКА В ВЕРИФИКАЦИИ БОЛЕЗНИ КРОНА У ДЕТЕЙ. КЛИНИЧЕСКИЙ СЛУЧАЙ

Diagnostics of Crohn’s disease, especially in children, presents a big challenge, given the low prevalence rate of this disease, polymorphism of the clinical manifestation and insufficient alertness of primary pediatricians relative to this pathology. As a result, untimely diagnostics, and, therefore, inadequate treatment, the disease takes an unfavourable turn, complications develop resulting in disabilities of little patients. The provided material and described clinical case study help physicians to identify Crohn’s disease in due time and refer the patient to a specialised medical establishment for additional examination and determining treatment tactics.Key words: inflammatory bowel disease, Crohn’s disease, diagnostics, children. (Pediatric Pharmacology. – 2010; 7(2):115-122)Диагностика болезни Крона, особенно у детей, представляет большую сложность, учитывая низкую распространенность заболевания, полиморфизм клинической картины и недостаточную настороженность педиатров первичного звена в отношении этой патологии. В результате несвоевременной диагностики и, как следствие, неадекватного лечения болезнь принимает неблагоприятное течение, развиваются осложнения, приводящие к инвалидизации маленьких пациентов. Представленный материал и описанный клинический случай помогут врачам вовремя заподозрить болезнь Крона и направить больного в специализированное медицинское учреждение для дообследования и определения тактики лечения. Ключевые слова: воспалительные заболевания кишечника, болезнь Крона, диагностика, дети. (Педиатрическая фармакология. – 2010; 7(2):115-122