ECONOMIC EFFICIENCY OF USING OF AIR SUPPLY DEVICES THAT SUPPLY AIR WITH SWIRL AND SPREAD AIR JETS

Наголошено на актуальності підтримання нормативних параметрів мікроклімату теплонапружених приміщень невеликого об'єму із щільним компонуванням обладнання, а також показано доцільність застосування в них такої енергоефективної схеми організації повітрообміну як витісняюча вентиляція. Проаналізовано недоліки повітророзподільних пристроїв систем витісняючої вентиляції. Запропоновано конструкцію малошвидкісного двокамерного панельно-секційного повітророзподільника для забезпечення ефективної роботи системи витісняючої вентиляції. Ці повітророзподільники дають змогу забезпечити рівномірність розподілу статичного тиску в корпусі повітророзподільника, а отже, і рівномірність витоку повітря у вентильований простір. Їх конструкція дає змогу ефективно регулювати витрату повітря. Представлено методику розрахунку поличкових відокремлювачів потоку розподільної камери малошвидкісного панельно-секційного повітророзподільника. Визначено конструкційні розміри та розроблено типоряд двокамерних малошвидкісних панельно-секційних повітророзподільників з різними коефіцієнтами живого перерізу повітророзподільної стінки та з одно – або двобічним повітророзподіленням. Запропоновано алгоритм добору таких повітророзподільників залежно від початкової швидкості сформованої струмини.Указано на актуальность поддержки допустимых параметров микроклимата теплонапряженных помещений небольшого объема с плотной компоновкой оборудования, а также показана целесообразность применения в них такой энергоэффективной схемы организации воздухообмена как вытесняющая вентиляция. Проанализированы недостатки воздухораспределительных устройств систем вытесняющей вентиляции и предложена конструкция малоскоростного двухкамерного панельно-секционного воздухораспределителя для обеспечения эффективной работы системы вытесняющей вентиляции. Эти воздухораспределители позволяют обеспечить равномерность распределения статического давления в корпусе самого воздухораспределителя, а следовательно, и равномерность истока воздуха в вентилируемое пространство. Их конструкция позволяет эффективно регулировать подачу воздуха. Представлена методика расчета полочек отделителей потока распределительной камеры малоскоростного панельно-секционного воздухораспределителя, определены конструкционные размеры и разработан типоряд двухкамерных малоскоростных панельно-секционных воздухораспределителей с разными коэффициентами живого сечения воздухораспределительной стенки и с одно- или двусторонним воздухораспределением. Предложен алгоритм отбора таких воздухораспределителей в зависимости от начальной скорости сформированной струи.Topicality of support of possible microclimate parameters of heat-intense small volume apartments with dense arrangement of equipment is stressed. The expedience of application there of such energy efficient chart of organization of ventilation as ousting ventilation is shown. The lack of air distributor devices of the systems of ousting ventilation is analysed. The construction of low-speed two-chamber panel-sectional air distributor is offered for providing effective work of the system of ousting ventilation. This air distributor allows providing evenness of distributing of static pressure in the corps of air distributor, and, consequently an evenness of air source in the ventilated space. Its construction allows effective regulating the expense of air. The method of calculation of shelves is represented to the separators stream of distributive chamber of low-speed panel-sectional air distributor. The construction sizes are certain and developed series the two-chamber low-speed panel-sectional air distributor with different coefficients of living to the cut of air distribution wall and with one – or bilateral air distribution. The algorithm of selection of such air distributor is offered depending on initial velocity of the formed stream

Clinical Observation of a Child with KID (Keratitis-Ichthyosis-Deafness) Syndrome

A clinical case of keratitis-ichthyosis-deafness (KID syndrome) in an infant is described. The article familia-rizes pediatricians and family doctors with difficulties in the diagnosis of this rare genetic disease in infants

Molecular characterization of PH-negative myeloproliferative neoplasms in Ukraine

Aim: The aim of this study was to examine the JAK2 V617F, the G1691A allele of factor V, and the G20210A prothrombin gene mutation status, and their predictive value for thrombosis in patients with Ph-negative myeloproliferative neoplasms (MPN) in Ukraine, with special emphasize to patient exposed to ionizing radiation due to the Chernobyl accident. Materials and Methods: There were 198 patients with Ph-negative MPN included in the study. Of these, 45 patients had experienced radiation exposure due to the Chernobyl accident. The JAK2 V617F mutation, the G1691A of factor V and the G20210A of prothrombin were detected by allele-specific polymerase chain reaction. Results: The polycythemia vera and essential thrombocythemia patients in unexposed group and Chernobyl patients were comparable in terms of the JAK2 V617F mutation prevalence with the frequency of anomaly corresponding well to the published data on unselected cases of these types of Ph-negative MPN. The JAK2 V617F mutation was less common on the border of statistical significance (p = 0.08) in Chernobyl primary myelofibrosis (PMF) patients than in non-exposed patients. JAK2 V617F positive patients had higher level of leukocytes (p = 0.03), hemoglobin (p =0.04) and splenomegaly (p = 0.04) than those without mutation. The JAK2 V617F mutation was strong predictor for thrombosis in essential thrombocytemia patients (relative risk=3.1, 95% CI = 1.7–16.4, p = 0.03). In PMF, the association with thrombosis was found for the G1691A allele of factor V (p = 0.03). The risk of thrombosis associated with the inherited thrombophilia in PMF patients was 7.0-fold (95% CI = 1.41–33.1, p = 0.03) higher than in polycythemia vera patients. The inherited thrombophilia increased risk of thrombotic complication 5.4-fold (95% CI = 1.41–18.17, p = 0.01) in overall cohort of Ph-negative myeloproliferative neoplasms patients. This trend continued in Chernobyl patients (p = 0.02), but not in unexposed cases. Conclusions: Our findings confirm previous results of other studies reporting that the JAK2 V617F mutation significantly and independently influences on a disease phenotype in Ph-negative MPN. The inherited thrombophilia is important risk factors of the thrombosis development in overall cohort primary myelofibrosis patients, and especially in disease developed following radiation exposure

Molecular characterization of PH-negative myeloproliferative neoplasms in Ukraine

The aim of this study was to examine the JAK2 V617F, the G1691A allele of factor V, and the G2021OA prothrombin gene mutation status, and their predictive value for thrombosis in patients with Ph-negative myeloproliferative neoplasms (MPN) in Ukraine, with special emphasize to patient exposed to ionizing radiation due to the Chernobyl accident. There were198 patients with Ph-negative MPN included in the study. Of these, 45 patients had experienced radiation exposure due to the Chernobyl accident. The JAK2 V617F mutation, the G1691A of factor V and the G20210A of prothrombin were detected by allele-specific polymerase chain reaction. The polycythemia vera and essential thrombocythemia patients in unexposed group and Chernobyl patients were comparable in terms of the JAK2 V617F mutation prevalence with the frequency of anomaly corresponding well to the published data on unselectcd cases of these types of Ph-negative MPN. The JAK2 V617F mutation was less common on the border of statistical significance (p = 0,08) in Chernobyl primary myelofibrosis (PMF) patients than in non-exposed patients. JAK2 V617F positive patients had higher level of leukocytes (p = 0,03), hemoglobin (p = 0,04) and splenomegaly (p = 0,04) than those without mutation. The JAK2 V617F mutation was strong predictor for thrombosis in essential thrombocytemia patients (relative risk = 3,1, 95 % CI = 1,7 - 16,4, p = 0,03). In PMF, the association with thrombosis was found for the G1691A allele of factor V (p = 0,03). The risk of thrombosis associated with the inherited thrombophilia in PMF patients was 7,0-foid (95 % CI = 1,41 - 33,1, p = 0,03) higher than in polycythemia vera patients. The inherited thrombophilia increased risk of thrombotic complication 5,4-fold (95 % CI = 1,41 - 18,17, p = 0,01) in overall cohort of Ph-negative myeloproliferative neoplasms patients. This trend continued in Chernobyl patients (p = 0,02), but not in unexposed cases. Conclusions: our findings confirm previous results of other studies reporting that the JAK2 V617F mutation significantly and independently influences on a disease phenotype in Ph-negative MPN. The inherited thrombophilia is important risk factors of the thrombosis development in overall cohort primary myelofibrosis patients, and especially in disease developed following radiation exposure. Key Words: Ph-negative myeloproliferative neoplasms, thrombosis, the JAK2 V617F mutation, the factor V gene G1691A, the prothrombin gene G20210A

Nutritional Deficiencies in Children of the First 3 Years of Life, According to a Multicenter Study in Ukraine

Taking into account the fact that in Ukraine today there is not enough researches that summarize the data on the nutritional status of young children, the prevalence of eating disorders and lack of basic macro- and micronutrients in children, the multicenter study on nutrition of children from 9 months to 3 years of life has been carried out. It was found that the present dietary intake of infants is unbalanced, contains excess energy and proteins, lack of zinc, iron, calcium, and vitamins A, D, E, B6, B12, B1. Due to unbalanced diet, the use of special infant formula instead of unmodified bovine milk in feeding young child can increase consumption of important nutrients (calcium, iron, iodine, vitamin E, D and folates)

Nutritional Deficiencies in Children of the First 3 Years of Life, According to a Multicenter Study in Ukraine

Taking into account the fact that in Ukraine today there is not enough researches that summarize the data on the nutritional status of young children, the prevalence of eating disorders and lack of basic macro- and micronutrients in children, the multicenter study on nutrition of children from 9 months to 3 years of life has been carried out. It was found that the present dietary intake of infants is unbalanced, contains excess energy and proteins, lack of zinc, iron, calcium, and vitamins A, D, E, B6, B12, B1. Due to unbalanced diet, the use of special infant formula instead of unmodified bovine milk in feeding young child can increase consumption of important nutrients (calcium, iron, iodine, vitamin E, D and folates)