Übertragungsfunktionen und exakte Bildrestaurierung bei digitalen Luftaufnahmen

Im Folgenden wird ein Verfahren zur pixelscharfen Bildrestaurierung von digitalen Luftbildaufnahmen entwickelt. Das Verfahren basiert auf der Berechnung der Verwaschungsfunktion an Kanten. Die Verwaschungsfunktion für Bildprofile wird als Bandmatrix angesetzt, die nun auch streng invertiert werden kann und damit eine exakte Rekonstruktion der Objektfunktion erlaubt. Aus der inversen Verwaschungsfunktion für Profile wird in der Folge ein zweidimensionales Filter zur Bildrestaurierung ermittelt. Das Verfahren wurde an Bildern der digitalen Luftbildkammern ADS40 und DMC angewendet und auch an mittelformatigen Kammern. Ganz grob lässt sich damit die Bildauflösung um den Faktor 2 steigern. Es setzt voraus, dass hochwertige Anfnahmeobjektive eingesetzt werden, so dass Objekte, die nur durch ein Pixel getrennt sind, im Bild nicht völlig verschmelzen

Breakdown of the Korringa Law of Nuclear Spin Relaxation in Metallic GaAs

We present nuclear spin relaxation measurements in GaAs epilayers using a new pump-probe technique in all-electrical, lateral spin-valve devices. The measured T1 times agree very well with NMR data available for T > 1 K. However, the nuclear spin relaxation rate clearly deviates from the well-established Korringa law expected in metallic samples and follows a sub-linear temperature dependence 1/T1 ~ T^0.6 for 0.1 K < T < 10 K. Further, we investigate nuclear spin inhomogeneities.Comment: 5 pages, 4 (color) figures. arXiv admin note: text overlap with arXiv:1109.633

HELIMAP: Rapid Large Scale Mapping Using Handheld LiDAR/CCD/GPS/INS Sensors on Helicopters.

The HELIMAP is a portable mapping system for quick helicopter deployment. It integrates high accuracy navigation sensors (GPS/INS) with Airborne Laser Scanner (ALS) and high-resolution digital (CCD) camera. This paper presents the system hardware and software components, system calibration and a road map from acquisition to mapping product

RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study

BACKGROUND: Although Temozolomide is effective against glioblastoma, the prognosis remains dismal and new regimens with synergistic activity are sought for. METHODS: In this phase-I/II trial, pegylated liposomal doxorubicin (Caelyx, PEG-Dox) and prolonged administration of Temozolomide in addition to radiotherapy was investigated in 63 patients with newly diagnosed glioblastoma. In phase-I, PEG-Dox was administered in a 3-by-3 dose-escalation regimen. In phase-II, 20 mg/m2 PEG-Dox was given once prior to radiotherapy and on days 1 and 15 of each 28-day cycle starting 4 weeks after radiotherapy. Temozolomide was given in a dose of 75 mg/m2 daily during radiotherapy (60 Gy) and 150-200 mg/m2 on days 1-5 of each 28-day cycle for 12 cycles or until disease progression. RESULTS: The toxicity of the combination of PEG-Dox, prolonged administration of Temozolomide, and radiotherapy was tolerable. The progression free survival after 12 months (PFS-12) was 30.2%, the median overall survival was 17.6 months in all patients including the ones from Phase-I. None of the endpoints differed significantly from the EORTC26981/NCIC-CE.3 data in a post-hoc statistical comparison. CONCLUSION: Together, the investigated combination is tolerable and feasible. Neither the addition of PEG-Dox nor the prolonged administration of Temozolomide resulted in a meaningful improvement of the patient's outcome as compared to the EORTC26981/NCIC-CE.3 data

Integration of radiation oncology teaching in medical studies by German medical faculties due to the new licensing regulations: an overview and recommendations of the consortium academic radiation oncology of the German Society for Radiation Oncology (DEGRO)

The new Medical Licensing Regulations 2025 (Ärztliche Approbationsordnung, ÄApprO) will soon be passed by the Federal Council (Bundesrat) and will be implemented step by step by the individual faculties in the coming months. The further development of medical studies essentially involves an orientation from fact-based to competence-based learning and focuses on practical, longitudinal and interdisciplinary training. Radiation oncology and radiation therapy are important components of therapeutic oncology and are of great importance for public health, both clinically and epidemiologically, and therefore should be given appropriate attention in medical education. This report is based on a recent survey on the current state of radiation therapy teaching at university hospitals in Germany as well as the contents of the National Competence Based Learning Objectives Catalogue for Medicine 2.0 (Nationaler Kompetenzbasierter Lernzielkatalog Medizin 2.0, NKLM) and the closely related Subject Catalogue (Gegenstandskatalog, GK) of the Institute for Medical and Pharmaceutical Examination Questions (Institut für Medizinische und Pharmazeutische Prüfungsfragen, IMPP). The current recommendations of the German Society for Radiation Oncology (Deutsche Gesellschaft für Radioonkologie, DEGRO) regarding topics, scope and rationale for the establishment of radiation oncology teaching at the respective faculties are also included

Radiotherapie des kutanen malignen Melanoms

In the past melanoma was considered intrinsically resistant to radiotherapy. In the last two decades radiotherapy was shown to be effective in the treatment of primary and recurrent tumors as well as in metastatic situations. This review is based on a PubMed search of the medical subject heading terms "radiotherapy and melanoma". Radiotherapy does not play an important role in the definitive treatment of cutaneous melanoma. An exception is medically inoperable patients with lentigo maligna, where definitive radiotherapy offers a treatment option with good local control rates. Postoperative radiotherapy reduces the risk of recurrence in patients with positive margins and in patients with desmoplastic melanoma and closed margins. Radiotherapy of the nodal basis should be considered in high-risk patients (size and number of involved nodes, extranodal spread, lymph node relapse). Palliative radiotherapy can effectively reduce the symptoms in patients with bone metastases. Local rdiosurgery should be preferred to whole brain radiotherapy. Radiotherapy may be simultaneously caombined with ipilimumab but should be combined with BRAF inhibitors only sequentially