3 research outputs found
Does malnutrition in utero determine diabetes and coronary heart disease in adulthood? Results from the Leningrad siege study, a cross sectional study
3-Nitro-4-Hydroxy-7-Propargylthio-[1,2,4]Triazolo[5,1c][1,2,4]Triazine And 3-Nitro-4-Hydroxy-7-Ethylthio-[1,2,4]Triazolo[5,1c][1,2,4]Triazine with Antiviral Activity
ΠΠ·ΠΎΠ±ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ ΠΎΡΠ½ΠΎΡΠΈΡΡΡ ΠΊ ΠΎΠ±Π»Π°ΡΡΠΈ ΠΎΡΠ³Π°Π½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Ρ
ΠΈΠΌΠΈΠΈ, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ ΠΊ 3-Π½ΠΈΡΡΠΎ-4-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-1,4-Π΄ΠΈΠ³ΠΈΠ΄ΡΠΎ-7-ΠΏΡΠΎΠΏΠ°ΡΠ³ΠΈΠ»ΡΠΈΠΎ-[1,2,4]ΡΡΠΈΠ°Π·ΠΎΠ»ΠΎ[5,1Ρ]-[1,2,4]ΡΡΠΈΠ°Π·ΠΈΠ½Ρ ΠΈ 3-Π½ΠΈΡΡΠΎ-4-Π³ΠΈΠ΄ΡΠΎΠΊΡΠΈ-1,4-Π΄ΠΈΠ³ΠΈΠ΄ΡΠΎ-7-ΡΡΠΈΠ»ΡΠΈΠΎ-[1,2,4]ΡΡΠΈΠ°Π·ΠΎΠ»ΠΎ[5,1Ρ][1,2,4]-ΡΡΠΈΠ°Π·ΠΈΠ½Ρ, ΡΠΎΡΠΌΡΠ» 4-5. Π’Π΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ΅Π·ΡΠ»ΡΡΠ°Ρ: ΠΏΠΎΠ»ΡΡΠ΅Π½Ρ Π½ΠΎΠ²ΡΠ΅ Π³Π΅ΡΠ΅ΡΠΎΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠΎΠ΅Π΄ΠΈΠ½Π΅Π½ΠΈΡ, ΠΎΠ±Π»Π°Π΄Π°ΡΡΠΈΠ΅ ΠΏΡΠΎΡΠΈΠ²ΠΎΠ²ΠΈΡΡΡΠ½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ Π² ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΈ ΡΠ½ΡΠ΅ΡΠΎΠ²ΠΈΡΡΡΠΎΠ². 1 ΡΠ°Π±Π»., 5 ΠΏΡ.FIELD: organic chemistry. SUBSTANCE: invention relates to the field of organic chemistry, namely to 3-nitro-4-hydroxy-1,4-dihydro-7-propargylthio-[1,2,4]triazolo[5,1c]-[1,2,4]triazine and 3-nitro-4-hydroxy-1,4-dihydro-7-ethylthio-[1,2,4]triazolo[5,1c][1,2,4]triazine of formulas 4-5. EFFECT: new heterocyclic compounds are obtained, having an antiviral activity relatively to enteroviruses. 1 cl, 1 tbl, 5 ex