Computational Notebooks for AI Education

Computational notebooks are documents that serve dual purposes: they serve as an archive format containing code, text, images and equations; but they can also be run like computer programs. This paper explores the use of these new computational notebooks to teach AI and introduces tools that we have developed — ICalico and Calysto — to facilitate that use. Not only do these new tools broaden the languages and contexts available to students exploring notebook-based AI computing, but they offer a new mode of teaching and learning for the AI classroom

Computational Notebooks for AI Education

Computational notebooks are documents that serve dual purposes: they serve as an archive format containing code, text, images and equations; but they can also be run like computer programs. This paper explores the use of these new computational notebooks to teach AI and introduces tools that we have developed — ICalico and Calysto — to facilitate that use. Not only do these new tools broaden the languages and contexts available to students exploring notebook-based AI computing, but they offer a new mode of teaching and learning for the AI classroom

On the optical properties of carbon nanotubes--Part I. A general formula for the dynamical optical conductivity

This paper is the first one of a series of two articles in which we revisit the optical properties of single-walled carbon nanotubes (SWNT). Produced by rolling up a graphene sheet, SWNT owe their intriguing properties to their cylindrical quasi-one-dimensional (quasi-1D) structure (the ratio length/radius is experimentally of order of 10^3). We model SWNT by circular cylinders of small diameters on the surface of which the conduction electron gas is confined by the electric field generated by the fixed carbon ions. The pair-interaction potential considered is the 3D Coulomb potential restricted to the cylinder. To reflect the quasi-1D structure, we introduce a 1D effective many-body Hamiltonian which is the starting-point of our analysis. To investigate the optical properties, we consider a perturbation by a uniform time-dependent electric field modeling an incident light beam along the longitudinal direction. By using Kubo's method, we derive within the linear response theory an asymptotic expansion in the low-temperature regime for the dynamical optical conductivity at fixed density of particles. The leading term only involves the eigenvalues and associated eigenfunctions of the (unperturbed) 1D effective many-body Hamiltonian, and allows us to account for the sharp peaks observed in the optical absorption spectrum of SWNT.Comment: Comments: 24 pages. Revised version. Accepted for publication in J.M.

Consumer Food Waste Behaviors in Relation to Open Date Label Misinterpretation

In the United States, the legal framework for product date labeling is minimal and varies across states. Manufacturers have the discretion to use any date label that they deem appropriate, and this lack of uniformity leaves room for misinterpretation by both retailers and consumers. Previous studies have examined consumer misinterpretation of date labels and how this lack of knowledge correlates to food waste behaviors. This study was aimed at understanding how consumers apply their knowledge about date labels to make decisions about purchasing and discarding food. The research was conducted via an intercept survey outside of a grocery store to obtain information directly from consumers. Survey results showed evidence that consumers often misunderstand the meaning of date labels, particularly “best-by” and “use-by.” Results also revealed that lack of understanding varied among different age groups. Decisions about purchasing and discarding food seem to be connected more to the apparent quality of food from a sensory perspective, rather than to a direct and significant link between the date label and the safety or quality of the product

Systematic review of the use of granulocyte-macrophage colony-stimulating factor in patients with advanced melanoma.

Several immunomodulatory checkpoint inhibitors have been approved for the treatment of patients with advanced melanoma, including ipilimumab, nivolumab and pembrolizumab. Talimogene laherparepvec is the first oncolytic virus to gain regulatory approval in the USA; it is also approved in Europe. Talimogene laherparepvec expresses granulocyte-macrophage colony-stimulating factor (GM-CSF), and with other GM-CSF-expressing oncolytic viruses in development, understanding the clinical relevance of this cytokine in treating advanced melanoma is important. Results of trials of GM-CSF in melanoma have been mixed, and while GM-CSF has the potential to promote anti-tumor responses, some preclinical data suggest that GM-CSF may sometimes promote tumor growth. GM-CSF has not been approved as a melanoma treatment. We undertook a systematic literature review of studies of GM-CSF in patients with advanced melanoma (stage IIIB-IV). Of the 503 articles identified, 26 studies met the eligibility criteria. Most studies investigated the use of GM-CSF in combination with another treatment, such as peptide vaccines or chemotherapy, or as an adjuvant to surgery. Some clinical benefit was reported in patients who received GM-CSF as an adjuvant to surgery, or in combination with other treatments. In general, outcomes for patients receiving peptide vaccines were not improved with the addition of GM-CSF. GM-CSF may be a valuable therapeutic adjuvant; however, further studies are needed, particularly head-to-head comparisons, to confirm the optimal dosing regimen and clinical effectiveness in patients with advanced melanoma

The non-self-adjointness of the radial momentum operator in n dimensions

The non self-adjointness of the radial momentum operator has been noted before by several authors, but the various proofs are incorrect. We give a rigorous proof that the $n$-dimensional radial momentum operator is not self- adjoint and has no self-adjoint extensions. The main idea of the proof is to show that this operator is unitarily equivalent to the momentum operator on $L^{2}[(0,\infty),dr]$ which is not self-adjoint and has no self-adjoint extensions.Comment: Some text and a reference adde

Metric properties of discrete time exclusion type processes in continuum

A new class of exclusion type processes acting in continuum with synchronous updating is introduced and studied. Ergodic averages of particle velocities are obtained and their connections to other statistical quantities, in particular to the particle density (the so called Fundamental Diagram) is analyzed rigorously. The main technical tool is a "dynamical" coupling applied in a nonstandard fashion: we do not prove the existence of the successful coupling (which even might not hold) but instead use its presence/absence as an important diagnostic tool. Despite that this approach cannot be applied to lattice systems directly, it allows to obtain new results for the lattice systems embedding them to the systems in continuum. Applications to the traffic flows modelling are discussed as well.Comment: 27 pages, 4 figures; minor errors corrected; details added to proofs of Theorems 4.1 and 5.

A comparison of acyltransferase activities in vitro with the distribution of fatty acids in lecithins and triglycerides in vivo

The location and configuration of a double bond in a fatty acid influences the rate of its acyltransferase‐catalyzed esterification to form lecithin and its distribution in vivo between the primary and secondary positions of triglycerides and lecithins.Saturated acids of shorter chain length are transferred at rates similar to the long chain unsaturated acids.The positional distributions of acids in the diglyceride units of liver triglycerides appear to be similar to that found in the lecithins.Acyltransferase activities measured in vitro have a considerable predictive value in terms of the ultimate distribution of fatty acids in glycerolipids in vivo.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141483/1/lipd0224.pd