Bruton\u27s tyrosine kinase supports gut mucosal immunity and commensal microbiome recognition in autoimmune arthritis

Bruton\u27s tyrosine kinase

Programming in C++ for engineering and science

""The book is lavishly illustrated with examples and exercises, which would make it both an ideal course companion and a book for private study. The author's abilities to explain briefly the history of computing and to write an engaging text are to be commended. If you buy only one text on programming in C++, then this should be the one for you.""-Carl M. O'Brien, International Statistical Review (2013), 8

Incretin response to acute exercise of differing intensities in obese women

"December 2013.""A Thesis presented to the Faculty of the Graduate School at the University of Missouri--Columbia Submitted in partial fulfillment of the requirements for the degree of Master of Science in Exercise Physiology in the Graduate School of University of Missouri--Columbia."Thesis advisor: Professor Jill Kanaley, Ph.D.[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The purpose of this study was to determine the incretin response to an acute continuous, moderate intensity (ModEx) and high-intensity interval (IntEx) exercise bout in obese women, and how previous exercise affects the glycemic and incretin response to a subsequent dinner meal. Sedentary, obese women (BMI>30kg/m2 ; 18-35 yr) participated in three conditions in a randomized, counterbalanced design: 1) No exercise/rest (NoEx), 2) continuous, moderate intensity exercise at 55% VO2max (ModEx), and 3) high-intensity aerobic interval exercise at 4 min 80% VO2max/3 min 50% VO2max (IntEx), followed by a standardized mixed dinner meal (800kcal; 65% CHO, 20% fat, 15% protein). Blood was sampled every 10 min for the first 160 min and then every 30 min for the final 2 h of the study day. Samples were analyzed for glucose, lactate, insulin, glucagon, GLP-1, GIP, and C-Peptide. Lactate concentrations increased during exercise in ModEx (6.2±0.7 mg/dL) and even greater in IntEx (15.4±2.5 mg/dL) conditions compared to NoEx (3.7±0.2 mg/dL) (p=0.01; p=0.001, respectively) which persisted into recovery (p=0.01). Glucose concentrations were not different between groups during exercise (p=0.38). Mean GIP and GLP-1 was not different between groups during exercise (p>0.05), but during recovery, GLP-1 concentrations were higher in ModEx condition compared to NoEx (p=0.03). In response to a mixed dinner meal, insulin and C-peptide iAUC was lower in ModEx condition compared to NoEx (p=0.002; p=0.005, respectively). No differences between groups were detected for glucose, GIP, GLP-1, hepatic insulin extraction, insulin secretion, or insulin sensitivity following the meal. Regardless of intensity, GLP-1 and GIP concentrations were increased during the latter stages of exercise, accompanied by a decrease in plasma insulin concentrations; opposite of the postprandial insulinotropic response previously associated with the incretin hormones. Insulin concentrations were reduced more so in the ModEx condition which may be attriIncludes bibliographical references (pages 58-63)

Fortran 77 for engineers and scientists: with an introduction to fortran 90

Indeksxxv, 884 hlm. :il,;24 cm

ADTs Data Structures and Problem Solving with C++ Ed.2

xxiv, 928 hlm.; Ind.; 27 c