1 research outputs found
Membraneless Gas-Separation Microfluidic Paper-Based Analytical Devices for Direct Quantitation of Volatile and Nonvolatile Compounds
This
work presents new chemical sensing devices called “membraneless
gas-separation microfluidic paper-based analytical devices”
(MBL-GS μPADs). MBL-GS μPADs were designed to make fabrication
of the devices simple and user-friendly. MBL-GS μPADs offer
direct quantitative analysis of volatile and nonvolatile compounds.
Porous hydrophobic membrane is not needed for gas-separation, which
makes fabrication of the device simple, rapid and low-cost. A MBL-GS
μPAD consists of three layers: “donor layer”,
“spacer layer”, and “acceptor layer”.
The donor and acceptor layers are made of filter paper with a printed
pattern. The donor and acceptor layers are mounted together with a
spacer layer in between. This spacer is a two-sided mounting tape,
0.8 mm thick, with a small disc cut out for the gas from the donor
zone to diffuse to the acceptor zone. Photographic image of the color
that is formed by the reagent in the acceptor layer is analyzed using
the ImageJ program for quantitation. Proof of concept of the MBL-GS
μPADs was demonstrated by analyzing standard solutions of ethanol,
sulfide, and ammonium. Optimization of the MBL-GS μPADs was
carried out for direct determination of ammonium in wastewaters and
fertilizers to demonstrate the applicability of the system to real
samples