4,418 research outputs found
Flavoring the gravity dual of N=1 Yang-Mills with probes
We study two related problems in the context of a supergravity dual to N=1
SYM. One of the problems is finding kappa symmetric D5-brane probes in this
particular background. The other is the use of these probes to add flavors to
the gauge theory. We find a rich and mathematically appealing structure of the
supersymmetric embeddings of a D5-brane probe in this background. Besides, we
compute the mass spectrum of the low energy excitations of N=1 SQCD (mesons)
and match our results with some field theory aspects known from the study of
supersymmetric gauge theories with a small number of flavors.Comment: 55 pages, 7 figures, LaTeX; v2: typos corrected, references added;
v3: typos correcte
Spherical harmonic decomposition applied to spatial-temporal analysis of human high-density EEG
We demonstrate an application of spherical harmonic decomposition to analysis
of the human electroencephalogram (EEG). We implement two methods and discuss
issues specific to analysis of hemispherical, irregularly sampled data.
Performance of the methods and spatial sampling requirements are quantified
using simulated data. The analysis is applied to experimental EEG data,
confirming earlier reports of an approximate frequency-wavenumber relationship
in some bands.Comment: 12 pages, 8 figures, submitted to Phys. Rev. E, uses APS RevTeX
style
Model of Low-pass Filtering of Local Field Potentials in Brain Tissue
Local field potentials (LFPs) are routinely measured experimentally in brain
tissue, and exhibit strong low-pass frequency filtering properties, with high
frequencies (such as action potentials) being visible only at very short
distances (10~) from the recording electrode. Understanding
this filtering is crucial to relate LFP signals with neuronal activity, but not
much is known about the exact mechanisms underlying this low-pass filtering. In
this paper, we investigate a possible biophysical mechanism for the low-pass
filtering properties of LFPs. We investigate the propagation of electric fields
and its frequency dependence close to the current source, i.e. at length scales
in the order of average interneuronal distance. We take into account the
presence of a high density of cellular membranes around current sources, such
as glial cells. By considering them as passive cells, we show that under the
influence of the electric source field, they respond by polarisation, i.e.,
creation of an induced field. Because of the finite velocity of ionic charge
movement, this polarization will not be instantaneous. Consequently, the
induced electric field will be frequency-dependent, and much reduced for high
frequencies. Our model establishes that with respect to frequency attenuation
properties, this situation is analogous to an equivalent RC-circuit, or better
a system of coupled RC-circuits. We present a number of numerical simulations
of induced electric field for biologically realistic values of parameters, and
show this frequency filtering effect as well as the attenuation of
extracellular potentials with distance. We suggest that induced electric fields
in passive cells surrounding neurons is the physical origin of frequency
filtering properties of LFPs.Comment: 10 figs, revised tex file and revised fig
Power supply of autonomous systems using solar modules
The article shows the methods of constructing autonomous decentralized energy systems from solar modules. It shows the operation of up DC inverter. It demonstrates the effectiveness of DC inverters with varying structure. The system has high efficiency and low level of conductive impulse noise and at the same time the system is practically feasible. Electrical processes have been analyzed to determine the characteristics of operating modes of the main circuit elements. Recommendations on using the converters have been given
Secondary metabolites from Rubiaceae species
This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae, published between 1990 and 2014. Iridoids, anthraquinones, triterpenes, indole alkaloids as well as other varying alkaloid subclasses, have shown to be the most common. These compounds have been mostly isolated from the genera Uncaria, Psychotria, Hedyotis, Ophiorrhiza and Morinda. The occurrence and distribution of iridoids, alkaloids and anthraquinones point out their chemotaxonomic correlation among tribes and subfamilies. From an evolutionary point of view, Rubioideae is the most ancient subfamily, followed by Ixoroideae and finally Cinchonoideae. The chemical biosynthetic pathway, which is not so specific in Rubioideae, can explain this and large amounts of both iridoids and indole alkaloids are produced. In Ixoroideae, the most active biosysthetic pathway is the one that produces iridoids; while in Cinchonoideae, it produces indole alkaloids together with other alkaloids. The chemical biosynthetic pathway now supports this botanical conclusion. © 2015 by the authors; licensee MDPI
LAGOVirtual: A Collaborative Environment for the Large Aperture GRB Observatory
We present the LAGOVirtual Project: an ongoing project to develop platform to
collaborate in the Large Aperture GRB Observatory (LAGO). This continental-wide
observatory is devised to detect high energy (around 100 GeV) component of
Gamma Ray Bursts, by using the single particle technique in arrays of Water
Cherenkov Detectors (WCD) at high mountain sites (Chacaltaya, Bolivia, 5300 m
a.s.l., Pico Espejo, Venezuela, 4750 m a.s.l., Sierra Negra, Mexico, 4650 m
a.s.l). This platform will allow LAGO collaboration to share data, and computer
resources through its different sites. This environment has the possibility to
generate synthetic data by simulating the showers through AIRES application and
to store/preserve distributed data files collected by the WCD at the LAGO
sites. The present article concerns the implementation of a prototype of
LAGO-DR adapting DSpace, with a hierarchical structure (i.e. country,
institution, followed by collections that contain the metadata and data files),
for the captured/simulated data. This structure was generated by using the
community, sub-community, collection, item model; available at the DSpace
software. Each member institution-country of the project has the appropriate
permissions on the system to publish information (descriptive metadata and
associated data files). The platform can also associate multiple files to each
item of data (data from the instruments, graphics, postprocessed-data, etc.).Comment: Second EELA-2 Conference Choroni, Venezuela, November 25th to 27th
200
One dimensional Coulomb-like problem in deformed space with minimal length
Spectrum and eigenfunctions in the momentum representation for 1D Coulomb
potential with deformed Heisenberg algebra leading to minimal length are found
exactly. It is shown that correction due to the deformation is proportional to
square root of the deformation parameter. We obtain the same spectrum using
Bohr-Sommerfeld quantization condition.Comment: 11 pages, typos corrected, references adde
Predictive Power of Strong Coupling in Theories with Large Distance Modified Gravity
We consider theories that modify gravity at cosmological distances, and show
that any such theory must exhibit a strong coupling phenomenon, or else it is
either inconsistent or is already ruled out by the solar system observations.
We show that all the ghost-free theories that modify dynamics of spin-2
graviton on asymptotically flat backgrounds, automatically have this property.
Due to the strong coupling effect, modification of the gravitational force is
source-dependent, and for lighter sources sets in at shorter distances. This
universal feature makes modified gravity theories predictive and potentially
testable not only by cosmological observations, but also by precision
gravitational measurements at scales much shorter than the current cosmological
horizon. We give a simple parametrization of consistent large distance modified
gravity theories and their predicted deviations from the Einsteinian metric
near the gravitating sources.Comment: 12 pages, Latex, to be published in New Journal of Physic
GATA3 protein as a MUC1 transcriptional regulator in breast cancer cells
INTRODUCTION: Recent studies have demonstrated that members of the GATA-binding protein (GATA) family (GATA4 and GATA5) might have pivotal roles in the transcriptional upregulation of mucin genes (MUC2, MUC3 and MUC4) in gastrointestinal epithelium. The zinc-finger GATA3 transcription factor has been reported to be involved in the growth control and differentiation of breast epithelial cells. In SAGE (serial analysis of gene expression) studies we observed an intriguing significant correlation between GATA3 and MUC1 mRNA expression in breast carcinomas. We therefore designed the present study to elucidate whether MUC1 expression is regulated by GATA3 in breast cancer cells. METHODS: Promoter sequence analysis of the MUC1 gene identified six GATA cis consensus elements in the 5' flanking region (GATA1, GATA3 and four GATA-like sequences). Chromatin immunoprecipitation and electrophoretic mobility-shift assays were employed to study the presence of a functional GATA3-binding site. GATA3 and MUC1 expression was analyzed in vitro with a GATA3 knockdown assay. Furthermore, expression of GATA3 and MUC1 genes was analyzed by real-time RT-PCR and immunohistochemistry on breast cancer-specific tissue microarrays. RESULTS: We confirmed the presence of a functional GATA3-binding site on the MUC1 promoter region in the MCF7 cell line. We determined that GATA3 knockdown assays led to a decrease in MUC1 protein expression in MCF7 and T47D cells. In addition, we detected a statistically significant correlation in expression between GATA3 and MUC1 genes at the mRNA and protein levels both in normal breast epithelium and in breast carcinomas (p = 0.01). GATA3 expression was also highly associated with estrogen receptor and progesterone receptor status (p = 0.0001) and tumor grade (p = 0.004) in breast carcinomas. CONCLUSION: Our study provides evidence indicating that GATA3 is probably a mediator for the transcriptional upregulation of MUC1 expression in some breast cancers
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