Association of two hub genes with the lung related traits and lung cancer from GWAS catalog database.

Association of two hub genes with the lung related traits and lung cancer from GWAS catalog database.</p

Expression levels in lung adenocarcinoma and lung squamous cell carcinoma cells in compression to normal tissues from GEPIA2.

A) SREK1. B) IRAK2. C) DDX3Y. D) C1QTNF2. The signature score is calculated by mean value of log2 (TPM + 1). The |Log2FC| cutoff of the expression of proposed biomarker was 1. The p-value cutoff of the expression of proposed biomarker was 0.01. The red box indicates the tumor samples while the gray one represents the normal tissues. E. Pathological Stage Plot of SREK1, IRAK2, DDX3Y and C1QTNF2 genes in lung cancer.</p

Fig 1 -

B Analysis of COPD differentially expressed genes (DEGs) in comparison to corresponding controls (A) Volcano plots of log fold changes in gene expression. (B) Identification of 63 common DEGs from blood and lung tissue datasets using VENNY. The overlapped area defines the shared DEGs of lung tissue and blood. (C) Heatmap of DEGs with a LogFC > 1.5. Red: up-regulation; green: down-regulation.</p