Assessment of the state of the art in life support environmental control for SEI

This paper defines the types of technology that would be used in a lunar base for environmental control and life support system and how it might relate to in situ materials utilization (ISMU) for the Space Exploration Initiative (SEI). There are three types of interaction between ISMU and the Environmental Control and Life Support System (ECLSS): (1) ISMU can reduce cost of water, oxygen, and possibly diluent gasses provided to ECLSS--a corollary to this fact is that the availability of indigenous resources can dramatically alter life support technology trade studies; (2) ISMU can use ECLSS waste systems as a source of reductant carbon and hydrogen; and (3) ECLSS and ISMU, as two chemical processing technologies used in spacecraft, can share technology, thereby increasing the impact of technology investments in either area

Prospective multi-center trial utilizing electronic brachytherapy for the treatment of endometrial cancer

<p>Abstract</p> <p>Background</p> <p>A modified form of high dose rate (HDR) brachytherapy has been developed called Axxent Electronic Brachytherapy (EBT). EBT uses a kilovolt X-ray source and does not require treatment in a shielded vault or a HDR afterloader unit. A multi-center clinical study was carried out to evaluate the success of treatment delivery, safety and toxicity of EBT in patients with endometrial cancer.</p> <p>Methods</p> <p>A total of 15 patients with stage I or II endometrial cancer were enrolled at 5 sites. Patients were treated with vaginal EBT alone or in combination with external beam radiation.</p> <p>Results</p> <p>The prescribed doses of EBT were successfully delivered in all 15 patients. From the first fraction through 3 months follow-up, there were 4 CTC Grade 1 adverse events and 2 CTC Grade II adverse events reported that were EBT related. The mild events reported were dysuria, vaginal dryness, mucosal atrophy, and rectal bleeding. The moderate treatment related adverse events included dysuria, and vaginal pain. No Grade III or IV adverse events were reported. The EBT system performed well and was associated with limited acute toxicities.</p> <p>Conclusions</p> <p>EBT shows acute results similar to HDR brachytherapy. Additional research is needed to further assess the clinical efficacy and safety of EBT in the treatment of endometrial cancer.</p

Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide

<p>Abstract</p> <p>Background</p> <p>Prions, the infectious agents that cause transmissible spongiform encephalopathies (TSEs), are relatively resistant to destruction by physical, enzymatic, and chemical treatments. Hydrolysis in boiling saturated calcium hydroxide (limewater) utilizes inexpensive chemicals to digest protein components of offal. The purpose of this work was to determine if incubating brain material from scrapie-infected sheep in near-boiling saturated calcium hydroxide solution (Ca(OH)₂) would abolish immunoreactivity of the infectious prion (PrP^Sc) as determined by western blot.</p> <p>Findings</p> <p>After incubating for as few as 10 minutes in saturated calcium hydroxide at 99°C, immunoreactivity of protease resistant bands by western blot analysis is completely lost.</p> <p>Conclusion</p> <p>Boiling in limewater may offer an alternative for disposal of carcasses and enable alternative uses for rendered products from potentially infected carcasses.</p

Atmospheric Heating and Wind Acceleration: Results for Cool Evolved Stars based on Proposed Processes

A chromosphere is a universal attribute of stars of spectral type later than ~F5. Evolved (K and M) giants and supergiants (including the zeta Aurigae binaries) show extended and highly turbulent chromospheres, which develop into slow massive winds. The associated continuous mass loss has a significant impact on stellar evolution, and thence on the chemical evolution of galaxies. Yet despite the fundamental importance of those winds in astrophysics, the question of their origin(s) remains unsolved. What sources heat a chromosphere? What is the role of the chromosphere in the formation of stellar winds? This chapter provides a review of the observational requirements and theoretical approaches for modeling chromospheric heating and the acceleration of winds in single cool, evolved stars and in eclipsing binary stars, including physical models that have recently been proposed. It describes the successes that have been achieved so far by invoking acoustic and MHD waves to provide a physical description of plasma heating and wind acceleration, and discusses the challenges that still remain.Comment: 46 pages, 9 figures, 1 table; modified and unedited manuscript; accepted version to appear in: Giants of Eclipse, eds. E. Griffin and T. Ake (Berlin: Springer

Vapor-compression evaporation system and method

According to one embodiment of the invention, a vapor-compression evaporation system includes a plurality of vessels in series each containing a feed having a nonvolatile component. A first set of the plurality of vessels includes vapor-compression evaporators and a second set of the plurality of vessels includes multi-effect evaporators. A mechanical compressor is coupled to the last vessel in the series of vapor-compression evaporators and is operable to receive a vapor therefrom. A turbine is coupled to, and operable to drive, the mechanical compressor. A pump is operable to deliver a cooling liquid to the mechanical compressor, and a tank is coupled to the mechanical compressor and is operable to separate liquid and vapor received from the mechanical compressor. A plurality of heat exchangers is coupled inside respective ones of the vessels, wherein the heat exchanger in the first vessel in the first set is operable to receive the vapor from the tank, and at least some of the vapor condenses therein. The heat of condensation provides the heat of evaporation to the first vessel in the first set, and at least some of the vapor inside the first vessel in the first set is delivered to the heat exchanger in the next vessel in the first set, whereby the condensing, evaporating, and delivering steps continue until the last vessel in the second set is reached.U

Vapor-compression evaporation system and method

According to one embodiment of the invention, a vapor-compression evaporation system includes a plurality of vessels in series each containing a feed having a nonvolatile component. A first set of the plurality of vessels includes vapor-compression evaporators and a second set of the plurality of vessels includes multi-effect evaporators. A mechanical compressor is coupled to the last vessel in the series of vapor-compression evaporators and is operable to receive a vapor therefrom. A turbine is coupled to, and operable to drive, the mechanical compressor. A pump is operable to deliver a cooling liquid to the mechanical compressor, and a tank is coupled to the mechanical compressor and is operable to separate liquid and vapor received from the mechanical compressor. A plurality of heat exchangers is coupled inside respective ones of the vessels, wherein the heat exchanger in the first vessel in the first set is operable to receive the vapor from the tank, and at least some of the vapor condenses therein. The heat of condensation provides the heat of evaporation to the first vessel in the first set, and at least some of the vapor inside the first vessel in the first set is delivered to the heat exchanger in the next vessel in the first set, whereby the condensing, evaporating, and delivering steps continue until the last vessel in the second set is reached.U

Vapor-compression evaporation system and method

According to one embodiment of the invention, a vapor-compression evaporation system includes a plurality of vessels in series each containing a feed having a nonvolatile component. A first set of the plurality of vessels includes vapor-compression evaporators and a second set of the plurality of vessels includes multi-effect evaporators. A mechanical compressor is coupled to the last vessel in the series of vapor-compression evaporators and is operable to receive a vapor therefrom. A turbine is coupled to, and operable to drive, the mechanical compressor. A pump is operable to deliver a cooling liquid to the mechanical compressor, and a tank is coupled to the mechanical compressor and is operable to separate liquid and vapor received from the mechanical compressor. A plurality of heat exchangers is coupled inside respective ones of the vessels, wherein the heat exchanger in the first vessel in the first set is operable to receive the vapor from the tank, and at least some of the vapor condenses therein. The heat of condensation provides the heat of evaporation to the first vessel in the first set, and at least some of the vapor inside the first vessel in the first set is delivered to the heat exchanger in the next vessel in the first set, whereby the condensing, evaporating, and delivering steps continue until the last vessel in the second set is reached.U

Vapor-compression evaporation system and method

According to one embodiment of the invention, a vapor-compression evaporation system includes a plurality of vessels in series each containing a feed having a nonvolatile component. A first set of the plurality of vessels includes vapor-compression evaporators and a second set of the plurality of vessels includes multi-effect evaporators. A mechanical compressor is coupled to the last vessel in the series of vapor-compression evaporators and is operable to receive a vapor therefrom. A turbine is coupled to, and operable to drive, the mechanical compressor. A pump is operable to deliver a cooling liquid to the mechanical compressor, and a tank is coupled to the mechanical compressor and is operable to separate liquid and vapor received from the mechanical compressor. A plurality of heat exchangers is coupled inside respective ones of the vessels, wherein the heat exchanger in the first vessel in the first set is operable to receive the vapor from the tank, and at least some of the vapor condenses therein. The heat of condensation provides the heat of evaporation to the first vessel in the first set, and at least some of the vapor inside the first vessel in the first set is delivered to the heat exchanger in the next vessel in the first set, whereby the condensing, evaporating, and delivering steps continue until the last vessel in the second set is reached.U