Individual fecundity dynamically predicts remaining life expectancy in medflies

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Senescence can play an essential role in modelling and estimation of vector based epidemiological indicators: demographical approach

In the paper basic epidemiological indicators, produced by an aging population of vectors, are calculated. In the study we follow two lines: calculations for demographically structured population and individual life-history approach. We discuss the advantages and limitations of these approaches and compare the results of our calculations with epidemiological indicators obtained for non-aging population of vectors.Gibraltar, age effect, disease control, gerontology

Multiplicity of photohadronization and photon--hadron scaling violation

The method of scaling transformations permitting to carry out the reconstruction of cross sections of $\gamma N$ and $\gamma\gamma$ interactions on the basis of cross sections of nucleon-(anti)nucleon interactions is suggested. The photon--hadron scaling violation is a consequence of dependence of scaling transformation parameter $\bar n(s)$ on the energy. The universal function $\bar n(s)$ is interpreted as the multiplicity of photohadronization. This function is established by processing the data on $\gamma p$ cross sections in the low energy region \sqrt{s}< 20 \GeV and is extrapolated to the high energy region up to \sqrt{s}\sim 200 \GeV. The results of the reconstruction of $\gamma N$ cross sections at high energies and of $\gamma\gamma$ ones at all energies are in a remarkable agreement with available experimental data.Comment: 5 pages, 3 figures; v2: reference correcte

On the mass composition of primary cosmic rays in the energy region 10^15-10^16 eV

The method of a determination of the Primary Cosmic Ray mass composition is presented. Data processing is based on the theoretical model representing the integral muon multiplicity spectrum as the superposition of the spectra corresponding to different kinds of primary nuclei. The method consists of two stages. At the first stage, the permissible intervals of primary nuclei fractions f_i are determined on the base of the EAS spectrum vs the total number of muons (E_mu > 235 GeV). At the second stage, the permissible intervals of f_i are narrowed by fitting procedure. We use the experimental data on high multiplicity muon events (n_mu > 114) collected at the Baksan underground scintillation telescope. Within the framework of three components (protons, helium and heavy nuclei), the mass composition in the region 10^15-10^16 eV has been defined: f_p = 0.235 +- 0.02, f_He = 0.290 +- 0.02$, f_H = 0.475 +- 0.03.Comment: 14 pages, 6 figure

An Age-Structured Extension to the Vectorial Capacity Model

Vectorial capacity and the basic reproductive number (R(0)) have been instrumental in structuring thinking about vector-borne pathogen transmission and how best to prevent the diseases they cause. One of the more important simplifying assumptions of these models is age-independent vector mortality. A growing body of evidence indicates that insect vectors exhibit age-dependent mortality, which can have strong and varied affects on pathogen transmission dynamics and strategies for disease prevention.Based on survival analysis we derived new equations for vectorial capacity and R(0) that are valid for any pattern of age-dependent (or age-independent) vector mortality and explore the behavior of the models across various mortality patterns. The framework we present (1) lays the groundwork for an extension and refinement of the vectorial capacity paradigm by introducing an age-structured extension to the model, (2) encourages further research on the actuarial dynamics of vectors in particular and the relationship of vector mortality to pathogen transmission in general, and (3) provides a detailed quantitative basis for understanding the relative impact of reductions in vector longevity compared to other vector-borne disease prevention strategies.Accounting for age-dependent vector mortality in estimates of vectorial capacity and R(0) was most important when (1) vector densities are relatively low and the pattern of mortality can determine whether pathogen transmission will persist; i.e., determines whether R(0) is above or below 1, (2) vector population growth rate is relatively low and there are complex interactions between birth and death that differ fundamentally from birth-death relationships with age-independent mortality, and (3) the vector exhibits complex patterns of age-dependent mortality and R(0) ∼ 1. A limiting factor in the construction and evaluation of new age-dependent mortality models is the paucity of data characterizing vector mortality patterns, particularly for free ranging vectors in the field