All-atomic source of squeezed vacuum with full pulse-shape control

We report on the generation of pulses of a low-frequency squeezed vacuum with noise suppression >2 dB below the standard quantum limit in a hot resonant 87 Rb vapor with polarization self-rotation. We demonstrate the possibility to precisely control the temporal profile of the squeezed noise quadrature by applying a calibrated longitudinal magnetic field, without degrading the maximum amount of squeezing

Persistence-driven durotaxis: Generic, directed motility in rigidity gradients

Cells move differently on substrates with different elasticities. In particular, the persistence time of their motion is higher on stiffer substrates. We show that this behavior will result in a net transport of cells directed up a soft-to-stiff gradient. Using simple random walk models with controlled persistence and stochastic simulations, we characterize this propensity to move in terms of the durotactic index measured in experiments. A one-dimensional model captures the essential features of this motion and highlights the competition between diffusive spreading and linear, wavelike propagation. Since the directed motion is rooted in a non-directional change in the behavior of individual cells, the motility is a kinesis rather than a taxis. Persistence-driven durokinesis is generic and may be of use in the design of instructive environments for cells and other motile, mechanosensitive objects.Comment: 5 pages, 4 figure