Comparison of Flexural Strength of Mineral Trioxide Aggregate, Calcium-enriched Mixture and BioAggregate

Introduction: The aim of this study was to compare the flexural strength of mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM), and BioAggregate (BA). Methods and Materials: In this study, the flexural strength of materials was measured using a 3-point bend test. After being prepared, MTA, CEM, and BA were inserted into the intra-putty molds using amalgam plugger. The specimens were covered with a sponge wetted with synthetic tissue fluid (STF) and incubated for 96 h. They were then subjected to a 3-point bend test using Universal Testing Machine. The Kruskal-Wallis and Mann-Whitney U tests were used to compare flexural strength in groups. In this study, P<0.05 was considered as the significant level. Results: There were significant differences between the three groups in terms of the flexural strength (P<0.001). The mean flexural strength in the BA, CEM, and MTA groups were 27.32±2, 9.09±1.16, and 10.25±1.6, respectively. Pairwise comparison showed significant differences between the three groups. Conclusion: This in vitro study showed that BA has the highest and CEM has the lowest flexural strength.Keywords: BioAggregate; CEM Cement; Flexural Strength; Mineral Trioxide Aggregate

Conservative Management of Asymptomatic Pneumoperitoneum; Report of Two Cases

Peptic ulcer disease is a common gastrointestinal disorder has been reduced in recent years due to effective new treatments. Peptic ulcer perforation is an emergent life-threatening condition causes pneumoperitoneum and septic shock. It often requires surgical procedures. We describe two cases of peptic ulcer perforation with only mild discomfort on the epigastric region since several months ago. The patients treated with high dose proton pump inhibitor and conservative actions without surgical procedures. Weekly follow up the cases showed that the clinical condition of patients remains stable without any new signs and symptoms. This report showed noninvasive treatment can be effective alone, in some cases with mild symptoms

Clinical Characteristics of Fatal Cases of COVID-19 in Tabriz, Iran: An Analysis of 111 Patients

Introduction: The rapid worldwide spread, in addition to the morbidity and mortality associated with the novel coronavirus disease 2019 (COVID-19), have raised concern throughout the world. Identifying the characteristics of patients who died of COVID-19 is essential to implement preventive measures. Objective: We aimed at investigating these characteristics among the Iranian population in Tabriz. Methods: In this case series, we analyzed clinical characteristics, laboratory parameters, and imaging findings of 111 patients with a reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 diagnosis who died during hospitalization. The studied patients had been admitted to the hospital between February 2020 and May 2020. Results: The median age of patients was 73 years (IQR, 62-82 years) and approximately 70% of them were male. The median oxygen saturation on admission was 88% (IQR, 80-92%) and dyspnea, cough, and fever were the most common presenting symptoms. Among comorbidities, diabetes, hypertension, and cardiovascular diseases were more frequently observed among patients who had a fatal outcome. While ground-glass opacity was the most commonly reported finding on chest computed tomography, 5% of the patients had no abnormal finding on imaging. Chloroquine was the most frequently used medication for treatment. Conclusion: Our results showed that the majority of COVID-19 deaths occurred in male elderly with decreased levels of oxygen saturation and elevated levels of lactate dehydrogenase and erythrocyte sedimentation rate on admission

Biomarkers for Transient Ischemic Attack: A Brief Perspective of Current Reports and Future Horizons

Cerebrovascular disease is the leading cause of long-term disability in the world and the third-leading cause of death in the United States. The early diagnosis of transient ischemic attack (TIA) is of great importance for reducing the mortality and morbidity of cerebrovascular diseases. Patients with TIA have a high risk of early subsequent ischemic stroke and the development of permanent nervous system lesions. The diagnosis of TIA remains a clinical diagnosis that highly relies on the patient’s medical history assessment. There is a growing list of biomarkers associated with different components of the ischemic cascade in the brain. In this review, we take a closer look at the biomarkers of TIA and their validity with a focus on the more clinically important ones using recent evidence of their reliability for practical usage

Albucasis: pioneer of the modern anorectal surgery

Albucasis is one of the world’s pioneers in surgery. In his book, “Al-Tasrif”, he described the surgical procedures and tools, as well as post-operative care in detail. He introduced colorectal surgeries in detail and used topical substances to accelerate recovery. Albucasis considered different approaches for anorectal surgeries and used them according to the complexity of the cases. Many of these methods were first invented by him and the effect of his ideas on modern surgical methods is evident. In this article, we discuss anorectal diseases treated by Albucasis using surgical procedures. Resumo: Albucasis foi um dos pioneiros do mundo todo em cirurgia. Em seu livro “Al-Tasrif”, ele descreveu os procedimentos e ferramentas cirúrgicas, bem como os cuidados pós-operatórios em detalhes. Ele incluiu cirurgias colorretais em detalhes e também utilizou substâncias tópicas para acelerar a recuperação. Albucasis considerou diferentes abordagens para cirurgias anorretais e as utilizou de acordo com a complexidade dos casos. Muitos desses métodos foram inventados por ele e o efeito de suas ideias nos métodos cirúrgicos modernos é evidente. Neste artigo, discutimos doenças anorretais tratadas por Albucasis utilizando procedimentos cirúrgicos

Long-term side effects and lingering symptoms post COVID-19 recovery

Since the Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), our understanding regarding the pathophysiology and clinical manifestations of this disease have been improving. However, we still have limited data on long-term effects and lingering symptoms of post COVID-19 recovery. Despite predilection of COVID-19 for lungs, multiple extra-pulmonary manifestations appear in multiple organs and biological systems and with continued infection and recovery worldwide. It is necessary that clinicians provide patients with previous SARS-CoV-2 infection with expectations of long-term effects during or after recovery from COVID-19. Herein, we review the long-term impact of COVID-19 on different organ systems reported from different clinical studies. Understanding risk factors and signs and symptoms of long-term consequences after recovery from COVID-19 will allow for proper follow-up and management of the disease post recovery

Concurrent chronic lymphocytic leukemia and COVID-19: A comprehensive review of epidemiological, diagnostic, and therapeutic challenges

A comprehensive review of the literature on chronic lymphocytic leukemia (CLL) patients and recommendations regarding the evaluation and treatment of these patients was conducted. The overall prevalence of CLL and COVID-19 concurrence was found to be 0.6% (95%CI: 0.5% to 0.7%). Diagnostic interaction between CLL and COVID-19 remains a major challenge. Also, CLL patients have a lower rate of anti-SARS-CoV-2 IgG development. Evidences show the unacceptable therapeutic outcome in these patients. Although the CLL-COVID-19 occurrence is associated with adverse clinical consequences, no general and standard agreement has yet been presented for the management and treatment of this disease

Clinical Characteristics of Fatal Cases of COVID-19 in Tabriz, Iran: An Analysis of 111 Patients

Introduction: The rapid worldwide spread, in addition to the morbidity and mortality associated with the novel coronavirus disease 2019 (COVID-19), have raised concern throughout the world. Identifying the characteristics of patients who died of COVID-19 is essential to implement preventive measures. Objective: We aimed at investigating these characteristics among the Iranian population in Tabriz. Methods: In this case series, we analyzed clinical characteristics, laboratory parameters, and imaging findings of 111 patients with a reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 diagnosis who died during hospitalization. The studied patients had been admitted to the hospital between February 2020 and May 2020. Results: The median age of patients was 73 years (IQR, 62-82 years) and approximately 70% of them were male. The median oxygen saturation on admission was 88% (IQR, 80-92%) and dyspnea, cough, and fever were the most common presenting symptoms. Among comorbidities, diabetes, hypertension, and cardiovascular diseases were more frequently observed among patients who had a fatal outcome. While ground-glass opacity was the most commonly reported finding on chest computed tomography, 5% of the patients had no abnormal finding on imaging. Chloroquine was the most frequently used medication for treatment. Conclusion: Our results showed that the majority of COVID-19 deaths occurred in male elderly with decreased levels of oxygen saturation and elevated levels of lactate dehydrogenase and erythrocyte sedimentation rate on admission