A fast, very-high-energy γ -ray flare from BL Lacertae during a period of multi-wavelength activity in June 2015

The mechanisms producing fast variability of the γ-ray emission in active galactic nuclei (AGNs) are under debate. The MAGIC telescopes detected a fast, very-high-energy (VHE, E > 100 GeV) γ-ray flare from BL Lacertae on 2015 June 15. The flare had a maximum flux of (1.5 ± 0.3) × 10-10 photons cm-2 s-1 and halving time of 26 ± 8 min. The MAGIC observations were triggered by a high state in the optical and high-energy (HE, E > 100 MeV) γ-ray bands. In this paper we present the MAGIC VHE γ-ray data together with multi-wavelength data from radio, optical, X-rays, and HE γ rays from 2015 May 1 to July 31. Well-sampled multi-wavelength data allow us to study the variability in detail and compare it to the other epochs when fast, VHE γ-ray flares have been detected from this source. Interestingly, we find that the behaviour in radio, optical, X-rays, and HE γ-rays is very similar to two other observed VHE γ-ray flares. In particular, also during this flare there was an indication of rotation of the optical polarization angle and of activity at the 43 GHz core. These repeating patterns indicate a connection between the three events. We also test modelling of the spectral energy distribution based on constraints from the light curves and VLBA observations, with two different geometrical setups of two-zone inverse Compton models. In addition we model the γ-ray data with the star-jet interaction model. We find that all of the tested emission models are compatible with the fast VHE γ-ray flare, but all have some tension with the multi-wavelength observations

The Great Markarian 421 Flare of 2010 February: Multiwavelength Variability and Correlation Studies

We report on variability and correlation studies using multiwavelength observations of the blazar Mrk 421 during the month of 2010 February, when an extraordinary flare reaching a level of ∼27 Crab Units above 1 TeV was measured in very high energy (VHE) γ-rays with the Very Energetic Radiation Imaging Telescope Array System (VERITAS) observatory. This is the highest flux state for Mrk 421 ever observed in VHE γ-rays. Data are analyzed from a coordinated campaign across multiple instruments, including VHE γ-ray (VERITAS, Major Atmospheric Gamma-ray Imaging Cherenkov), high-energy γ-ray (Fermi-LAT), X-ray (Swift, Rossi X-ray Timing Experiment, MAXI), optical (including the GASP-WEBT collaboration and polarization data), and radio (Metsahovi, Owens Valley Radio Observatory, University of Michigan Radio Astronomy Observatory). Light curves are produced spanning multiple days before and after the peak of the VHE flare, including over several flare "decline" epochs. The main flare statistics allow 2 minute time bins to be constructed in both the VHE and optical bands enabling a cross-correlation analysis that shows evidence for an optical lag of ∼25-55 minutes, the first time-lagged correlation between these bands reported on such short timescales. Limits on the Doppler factor (δ ⪆ 33) and the size of the emission region (δ-1RB≲ 3.8 × 1013cm) are obtained from the fast variability observed by VERITAS during the main flare. Analysis of 10 minute binned VHE and X-ray data over the decline epochs shows an extraordinary range of behavior in the flux-flux relationship, from linear to quadratic to lack of correlation to anticorrelation. Taken together, these detailed observations of an unprecedented flare seen in Mrk 421 are difficult to explain with the classic single-zone synchrotron self-Compton model

Broadband characterisation of the very intense TeV flares of the blazar 1ES 1959+650 in 2016

1ES 1959+650 is a bright TeV high-frequency-peaked BL Lac object exhibiting interesting features like "orphan" TeV flares and broad emission in the high-energy regime that are difficult to interpret using conventional one-zone Synchrotron Self-Compton (SSC) scenarios. We report the results from the Major Atmospheric Gamma Imaging Cherenkov (MAGIC) observations in 2016 along with the multi-wavelength data from the Fermi Large Area Telescope (LAT) and Swift instruments. MAGIC observed 1ES 1959+650 with different emission levels in the very-high-energy (VHE, E> 100 GeV) gamma -ray band during 2016. In the long-term data, the X-ray spectrum becomes harder with increasing flux and a hint of a similar trend is also visible in the VHE band. An exceptionally high VHE flux reaching similar to 3 times the Crab Nebula flux was measured by MAGIC on the 13 and 14 of June, and 1 July 2016 (the highest flux observed since 2002). During these flares, the high-energy peak of the spectral energy distribution (SED) lies in the VHE domain and extends up to several TeV. The spectrum in the gamma -ray (both Fermi-LAT and VHE bands) and the X-ray bands are quite hard. On 13 June and 1 July 2016, the source showed rapid variations in the VHE flux within timescales of less than an hour. A simple one-zone SSC model can describe the data during the flares requiring moderate to large values of the Doppler factors (delta >= 30-60). Alternatively, the high-energy peak of the SED can be explained by a purely hadronic model attributed to proton-synchrotron radiation with jet power L-jet similar to 10(46) erg s(-1) and under high values of the magnetic field strength (similar to 100 G) and maximum proton energy (similar to few EeV). Mixed lepto-hadronic models require super-Eddington values of the jet power. We conclude that it is difficult to get detectable neutrino emission from the source during the extreme VHE flaring period of 2016

First multi-wavelength campaign on the gamma-ray-loud active galaxy IC 310

Context. The extragalactic very-high-energy gamma-ray sky is rich in blazars. These are jetted active galactic nuclei that are viewed at a small angle to the line-of-sight. Only a handful of objects viewed at a larger angle are so far known to emit above 100 GeV. Multi-wavelength studies of such objects up to the highest energies provide new insights into the particle and radiation processes of active galactic nuclei.Aims. We aim to report the results from the first multi-wavelength campaign observing the TeV detected nucleus of the active galaxy IC 310, whose jet is observed at a moderate viewing angle of 10 degrees-20 degrees.Methods. The multi-instrument campaign was conducted between 2012 November and 2013 January, and involved observations with MAGIC, Fermi, INTEGRAL, Swift, OVRO, MOJAVE and EVN. These observations were complemented with archival data from the AllWISE and 2MASS catalogs. A one-zone synchrotron self-Compton model was applied to describe the broadband spectral energy distribution.Results. IC 310 showed an extraordinary TeV flare at the beginning of the campaign, followed by a low, but still detectable TeV flux. Compared to previous measurements in this energy range, the spectral shape was found to be steeper during the low emission state. Simultaneous observations in the soft X-ray band showed an enhanced energy flux state and a harder-when-brighter spectral shape behavior. No strong correlated flux variability was found in other frequency regimes. The broadband spectral energy distribution obtained from these observations supports the hypothesis of a double-hump structure.Conclusions. The harder-when-brighter trend in the X-ray and VHE emission, observed for the first time during this campaign, is consistent with the behavior expected from a synchrotron self-Compton scenario. The contemporaneous broadband spectral energy distribution is well described with a one-zone synchrotron self-Compton model using parameters that are comparable to those found for other gamma-ray-emitting misaligned blazars

Measurement of the extragalactic background light using MAGIC and Fermi-LAT gamma-ray observations of blazars up to z=1

We present a measurement of the extragalactic background light (EBL) based on a joint likelihood analysis of 32 gamma-ray spectra for 12 blazars in the redshift range z = 0.03-0.944, obtained by the MAGIC telescopes and Fermi-LAT. The EBL is the part of the diffuse extragalactic radiation spanning the ultraviolet, visible, and infrared bands. Major contributors to the EBL are the light emitted by stars through the history of the Universe, and the fraction of it that was absorbed by dust in galaxies and re-emitted at longer wavelengths. The EBL can be studied indirectly through its effect on very high energy photons that are emitted by cosmic sources and absorbed via gamma gamma interactions during their propagation across cosmological distances. We obtain estimates of the EBL density in good agreement with state-of-the-art models of the EBL production and evolution. The 1 sigma upper bounds, including systematic uncertainties, are between 13 per cent and 23 per cent above the nominal EBL density in the models. No anomaly in the expected transparency of the Universe to gamma-rays is observed in any range of optical depth. We also perform a wavelength-resolved EBL determination, which results in a hint of an excess of EBL in the 0.18-0.62 mu m range relative to the studied models, yet compatible with them within systematics

Monitoring of the radio galaxy M 87 during a low -emission state from m 2012 to 2015 with MAGIC

M 87 is one of the closest (z = 0.004 36) extragalactic sources emitting at very high energies (VHF, E > 100 GeV). The aim of this work is to locale the region of the VHF gamma-ray emission and to describe the observed broad-band spectral energy distribution (SED) during the low VHF gamma-ray state. The data from M 87 collected between 2012 and 2015 as part of a MAGIC monitoring programme are analysed and combined with multiwavelength data from Fermi-LAT, Chandra, HST, FVN, VLBA, and the Liverpool Telescope. The averaged VHE gamma-ray spectrum can be fitted from 100 GeV to 10 TeV with a simple power law with a photon index of (-2.41 0.07), while the integral flux above 300 GeV is (1.44 0.13) x 10-12 cm 2 s I. During the campaign between 2012 and 2015, M87 is generally found in a low-emission state at all observed wavelengths. The VIIE gamma-ray flux from the present 2012-2015M 87 campaign is consistent with a constant flux with some hint of variability ( 3 a) on a daily time-scale in 2013. The low-state gamma-ray emission likely originates from the same region as the flare-state emission. Given the broad-band SED, both a leptonic synchrotron self-Compton and a hybrid photohadronic model reproduce the available data well, even if the latter is preferred. We note, however, that the energy stored in the magnetic field in the leptonic scenario is very low, suggesting a matter-dominated emission region

Periastron Observations of TeV Gamma-Ray Emission from a Binary System with a 50-year Period

We report on observations of the pulsar/Be star binary system PSR J2032+4127/MT91 213 in the energy range between 100 GeV and 20 TeV with the Very Energetic Radiation Imaging Telescope Array and Major Atmospheric Gamma Imaging Cherenkov telescope arrays. The binary orbit has a period of approximately 50 years, with the most recent periastron occurring on 2017 November 13. Our observations span from 18 months prior to periastron to one month after. A new point-like gamma-ray source is detected, coincident with the location of PSR J2032+4127/MT91 213. The gamma-ray light curve and spectrum are well characterized over the periastron passage. The flux is variable over at least an order of magnitude, peaking at periastron, thus providing a firm association of the TeV source with the pulsar/Be star system. Observations prior to periastron show a cutoff in the spectrum at an energy around 0.5 TeV. This result adds a new member to the small population of known TeV binaries, and it identifies only the second source of this class in which the nature and properties of the compact object are firmly established. We compare the gamma-ray results with the light curve measured with the X-ray Telescope on board the Neil Gehrels Swift Observatory and with the predictions of recent theoretical models of the system. We conclude that significant revision of the models is required to explain the details of the emission that we have observed, and we discuss the relationship between the binary system and the overlapping steady extended source, TeV J2032+4130

Electrochemically generated peryleniumyl-hexafluorophosphate and hexafluoroarsenate: new one-dimensional metals

Compounds of stoichiometry (pe)2(PF6)1.1 × 0.8CH2Cl2(1) (pe = perylene), (pe)2(AsF6)1.1 × 0.7 CH2Cl2 (2), (pe)2(PF6)1.4 × 0.6 THF (3), (pe)2(AsF6)1.5 × 0.5 THF (4) and (pe)3(SbF6)2 × 0.75 CH2Cl2 (5) have been obtained as crystalline samples by electrochemical deposition from CH2Cl2 [(1), (2) and (5)] or from THF [(3) and (4)] solutions of perylene, containing the appropriate counterion. The three compounds (1)-(3) crystallize in isomorphous orthorhombic lattices. (1) forms black needles: space group Pnmn with a = 4.285 Å, b = 12.915 Å and c = 14.033 Å, z = 1. (2) gives black needles, orthorhombic space group Pnmn with a = 4.294 Å, b = 13.077 Å, and c = 14.132 Å, z = 1. The structures of (1) and (2) were solved by direct methods and refined by least squares to final R = 0.148 and R = 0.088 based on 476 and 322 observed reflections. The perylene forms segregated stacks in direction of the a-axis with interplanar distances of 3.40 Å and an angle of 37.7° between the bc-plane and the perylene. The channels between the segregated stacks are filled by anions and solvent molecules. The d.c. conductivities (four probe measurements) of (1)-(4) fall in the range of 70–1200Ω−1. cm−1 at room temperature. The conductivities show a metallic regime down to about 200°K and drop off below that temperature

miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly

Airway mucociliary regeneration and function are key players for airway defense and are impaired in chronic obstructive pulmonary disease (COPD). Using transcriptome analysis in COPD-derived bronchial biopsies, we observed a positive correlation between cilia-related genes and microRNA-449 (miR449). In vitro, miR449 was strongly increased during airway epithelial mucociliary differentiation. In vivo, miR449 was upregulated during recovery from chemical or infective insults. miR0449(-/-) mice (both alleles are deleted) showed impaired ciliated epithelial regeneration after naphthalene and Haemophilus influenzae exposure, accompanied by more intense inflammation and emphysematous manifestations of COPD. The latter occurred spontaneously in aged miR449(-/-) mice. We identified Aurora kinase A and its effector target HDAC6 as key mediators in miR449-regulated ciliary homeostasis and epithelial regeneration. Aurora kinase A is downregulated upon miR449 overexpression in vitro and upregulated in miR449(-/-) mouse lungs. Accordingly, imaging studies showed profoundly altered cilia length and morphology accompanied by reduced mucociliary clearance. Pharmacological inhibition of HDAC6 rescued cilia length and coverage in miR449(-/-) cells, consistent with its tubulin-deacetylating function. Altogether, our study establishes a link between miR449, ciliary dysfunction, and COPD pathogenesis

MAGIC observations of the diffuse γ -ray emission in the vicinity of the Galactic center

Aims. In the presence of a sufficient amount of target material, γ-rays can be used as a tracer in the search for sources of Galactic cosmic rays (CRs). Here we present deep observations of the Galactic center (GC) region with the MAGIC telescopes and use them to infer the underlying CR distribution and to study the alleged PeV proton accelerator at the center of our Galaxy. Methods. We used data from ≈100 h observations of the GC region conducted with the MAGIC telescopes over five years (from 2012 to 2017). Those were collected at high zenith angles (58-70 deg), leading to a larger energy threshold, but also an increased effective collection area compared to low zenith observations. Using recently developed software tools, we derived the instrument response and background models required for extracting the diffuse emission in the region. We used existing measurements of the gas distribution in the GC region to derive the underlying distribution of CRs. We present a discussion of the associated biases and limitations of such an approach. Results. We obtain a significant detection for all four model components used to fit our data (Sgr A∗, "Arc", G0.9+0.1, and an extended component for the Galactic Ridge). We observe no significant difference between the γ-ray spectra of the immediate GC surroundings, which we model as a point source (Sgr A∗) and the Galactic Ridge. The latter can be described as a power-law with index 2 and an exponential cut-off at around 20 TeV with the significance of the cut-off being only 2σ. The derived cosmic-ray profile hints to a peak at the GC position and with a measured profile index of 1.2 ± 0.3 is consistent with the 1/r radial distance scaling law, which supports the hypothesis of a CR accelerator at the GC. We argue that the measurements of this profile are presently limited by our knowledge of the gas distribution in the GC vicinity