Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

DPA8993-KN.Dissertation III.Sp16.Norman-Major,Kristen

Independent work with chair/mentor to write chapter 3 (Methodology) and get IRB approval. Completion will then lead to Dissertation Proposal Defense (provided comprehensive exams have been passed)

GPA8506-DPA.AdvancedSeminarInPublicPolicy.SP15.Norman-Major,Kris

This course examines the theoretical and philosophical approaches used to systematically examine the public policy process. Because no single theory or model can adequately describe the complexities of this process, the analytical frameworks and assumptions of the major approaches to policy analysis are emphasized, and emerging theories explored. In individual assignments, students are encouraged to examine policy issues and frameworks that relate to potential dissertation topics

DPA8995-KN.Dissertation V.F16.Norman-Major,Kristen

Independent work with chair/mentor writing up analysis and conclusions. Outcome is finished dissertation that will go to final defense

DPA8995-KN1.Dissertation V.F16.Norman-Major,Kristen

Independent work with chair/mentor writing up analysis and conclusions. Outcome is finished dissertation that will go to final defense

GPA8993-KN1.Dissertation III.Sp14.Norman-Major,Kristen

Independent work with chair/mentor to write chapter 3 (Methodology) and get IRB approval. Completion will then lead to Dissertation Proposal Defense (provided comprehensive exams have been passed)

GPA8992-KN.Dissertation II.Sp15.Norman-Major,Kristen

Independent work with chair/mentor to write chapters 1(Introduction) and 2 (Literature Review)