Evaluation of Demographic Characteristics and Therapeutic Response to ocular Chemical Burn in Patients Referred to Eye Emergency Department of Farshchian Hospital in 2015-2016

Objective:The chemical eye burn is one of the major emergencies in the ophthalmology that will result in irreparable complications in case of inappropriate and timely treatment in severe casesMaterial and Methods:In this cross-sectional study 250 patients with ocular chemical burn who   referred to Farshchian Hospital were enrolled. Demographic characteristic and information regarding the burn were obtained. The Hughes-Roper-Hall classification was used for grading the severity of injury. All patients reevaluated 6 weeks later after injury.Results:Of 250 patients with complete follow up 155 cases ( 62% ) were male and 95 cases ( 38 % ) were female. Chemical injury were more common in the 20-40 years age group ( 108 case = 43/2 % ).The most common cause of chemical injury were occupational injury( 120 case = 48 % ).127 case (50/8 % ) of patients referred during The first hour after injury. The most common material of injury was acid in 102 cases (40/8 % ).Grade I burn was seen in 92 cases ( 36/8 % ) and grade IV in 30 cases ( 12 % ).Grading of the injury was related to the referring time after chemical burn. Severity of injury was more in alkaline burn.In 50 % of grade IV causes the burn had alkaline origin, however only 13/3 % of acid burn had grade IV severity. ( p : 0/001)Conclusion:The incidence of ocular chemical burn was approximately 2/19 % of all patients who referred to emergency ophthalmology service .According to this study ocular injury are more common in the men 20-40 years age group. The most common cause was occupational injury. Delay in referring and alkaline material were poor prognostic factor

In patients suffering from idiopathic central serous chorioretinopathy, anxiety scores are higher than in healthy controls, but do not vary according to sex or repeated central serous chorioretinopathy

Idiopathic central serous chorioretinopathy (CSCR) is a relatively common ophthalmic disorder characterized by the development of a serous detachment of the sensory retina. Psychophysiological factors may trigger or maintain CSCR, though, surprisingly, the association between CSCR and anxiety has yet to be studied. The aims of the present study were threefold: to determine whether 1) Iranian patients with CSCR have higher scores for anxiety, 2) anxiety is lower, if CSCR has been experienced twice, and whether 3) anxiety scores differ between sexes.; A total of 30 patients with CSCR and 30 healthy age-and sex-matched controls took part in the study. A brief face-to-face interview was conducted covering demographic variables and history and occurrence of CSCR and assessing anxiety.; Compared to healthy controls, anxiety was significantly higher in both first-time and second-time CSCR patients. In CSCR patients, anxiety scores did not differ between sexes.; Higher anxiety scores were observed in Iranian patients with CSCR, irrespective of whether this was the first or second occurrence of CSCR. This suggests there is no psychological adaptation in terms of reduced anxiety among patients with repeated CSCR

Premature Loss of Permanent Teeth in Allgrove (4A) Syndrome in Two Related Families

Background: Allgrove syndrome is a rare autosomal recessive condition characterized by adrenal insufficiency, achalasia, alacrima and occasionally autonomic disturbances. Mutations in the AAAS gene, on chromosome 12q13 have been implicated as a cause of this disorder. Case(s) Presentation: We present various manifestations of this syndrome in two related families each with two affected siblings in which several members had symptoms including reduced tear production, mild developmental delay, achalasia, neurological disturbances and also premature loss of permanent teeth in two of them, Conclusion: The importance of this report is dental involvement (loss of permanent teeth) in Allgrove syndrome that has not been reported in literature

Non-linear associations between retinal nerve fibre layer (RNFL) and positive and negative symptoms among men with acute and chronic schizophrenia spectrum disorder

Schizophrenia Spectrum Disorder (SSD) is a chronic psychiatric disorder with modest treatment outcomes. Changes in neuronal morphology may be associated with the symptomatology of SSD. In the present study, we compared the retinal nerve fibre layer thickness (RNFLT) of typically developed adults with that of individuals with SSD in both acute and chronic stages.; Fifteen healthy adult males (mean age: 36.40 years) and 30 individuals with SSD (mean age: 37.9 years) took part in the study. Among the latter, 15 had a chronic mean SSD for 15.33 years, while 15 were in an acute psychotic phase with a mean illness duration of 12.20 years. Experts rated positive and negative symptoms of SSD. Retinal nerve fibre layer thickness (RNFLT) of all participants was measured with optical coherence tomography (OCT).; Compared to healthy controls, individuals with acute SSD had the lowest macula thickness in the right eye. For nerve fiber layer atrophy, participants with acute SSD showed the largest atrophy (right eye, inferior quadrant). For retinal thickness and macular volume cube, compared to healthy controls, participants with acute SSD had the lowest thickness in the subfield of the right eye. Non-linear associations were observed between RNFL and positive and negative symptoms: e.g., for macula central and subfoveal thickness (left and right eye) and for participants with both acute and chronic SSD, exclusively positive and exclusively negative symptoms (as opposed to prevalently negative with some positive symptoms or prevalently positive with some negative symptoms) were associated with lower volumes. In participants with acute SSD, a longer disease duration was associated with thicker RNFL, while in participants with a chronic SSD a longer disease duration was associated with a thinner RNFL.; The present results confirm previous findings that specific neuronal morphological abnormalities can be observed among individuals with SSD. The non-linear associations between neuronal alterations and positive and negative symptomatology suggested that higher pronounced SSD severity appears to be particularly related to morphological changes. Disease duration and RNFL thickness were linearly associated, though, in opposite directions depending on the chronic or acute state

Visual impairment was related to educational level but not to cognitive performance among adults in their 60s

Older people are at greater risk of both physical impairments and cognitive decline. Although previous studies have examined whether visual and cognitive impairments are associated, findings have been mixed with cognitive performance only crudely assessed. Nonetheless, it remains possible that this association becomes stronger with age. Accordingly, in the present study, we tested the hypothesis that older people with visual impairments have poorer cognitive performance than healthy controls. To this end, we employed validated tools to assess both visual-related and visual-unrelated cognitive skills. A total of 30 older adults (mean age: M = 63.98 years, 30% females) with poor vision (logMAR value 1.0 or higher) and 30 gender- and age-matched healthy controls with no visual impairments (logMAR value 0.2 or lower) took part in this cross-sectional study. After a careful medical and psychiatric examination, participants underwent thorough cognitive testing for working and long-term memory and attention. Cognitive performance did not differ between those with and without visual impairments, though better cognitive performance scores were associated with higher educational level. Among older people, visual impairment was unrelated to cognitive performance. Rather, cognitive function was related to level of education