Two-particle correlation from a relativistic fluid with a first order phase transition

We numerically calculate two-particle correlation functions of CERN-SPS 158 A GeV Pb+Pb central collisions based on a (3+1)-dimensional relativistic hydrodynamics with a first order phase transition. We analyze the pair momentum dependence of pion source sizes extracted from the Yano-Koonin-Podgoretski\u{\i} (YKP) parametrization which is expected to give the source sizes directly. We find that, even in the case of the first order phase transition, the collective expansion and surface dominant freeze-out of the fluid naturally lead to the opaque source for which the interpretation of the temporal source parameter as the emission duration breaks down.Comment: LaTeX, 4pages, 2 figures. To appear in the Proceedings of the International Conference on Quark Nuclear Physics, Adelaide, Australia, 21-25 February, 200

Analysis of one- and two-particle spectra at RHIC based on a hydrodynamical model

We calculate the one-particle hadronic spectra and correlation functions of pions based on a hydrodynamical model. Parameters in the model are so chosen that the one-particle spectra reproduce experimental results of $\sqrt{s}=130A$GeV Au+Au collisions at RHIC. Based on the numerical solution, we discuss the space-time evolution of the fluid. Two-pion correlation functions are also discussed. Our numerical solution suggests the formation of the quark-gluon plasma with large volume and low net baryon density.Comment: LaTeX, 4pages, 4 figures. To appear in the proceedings of Fourth International Conference on Physics and Astrophysics of Quark-Gluon Plasma (ICPAQGP-2001), Nov 26-30, 2001, Jaipur, Indi

Sub-microsecond response digital controller for POL

This paper will discuss about the proposed hard-ware logic type digital controller for on-board SMPS which has a very small time-delay in control loop. Some experimental has been done including estimation of the load current change experiment and the frequency characteristic of open loop transfer function. These result reveal the proposed circuit could be suppressed the time delay to sub-microsecond order. To use the multi-phase system reduces the output ripple.7th International Power Electronics Conference, IPEC-Hiroshima - ECCE Asia 2014; Hiroshima; Japan; 18 May 2014 through 21 May 201

Dynamically Integrated Transport Approach for High-Energy Nuclear Collisions at High Baryon Density

To explore the structure of the QCD phase diagram in high baryon density domain, several high-energy nuclear collision experiments in a wide range of beam energies are currently performed or planned using many accelerator facilities. In these experiments search for a first-order phase transition and the QCD critical point is one of the most important topics. To find the signature of the phase transition, experimental data should be compared to appropriate dynamical models which quantitatively describe the process of the collisions. In this study we develop a new dynamical model on the basis of the non-equilibrium hadronic transport model JAM and 3+1D hydrodynamics. We show that the new model reproduce well the experimental beam-energy dependence of hadron yields and particle ratio by the partial thermalization of the system in our core-corona approach.Comment: 4 pages, 3 figures; contribution to the proceedings of the 8th International Conference on Quarks and Nuclear Physics (QNP2018), Tsukuba, November 13-17, 201

spERt Technology: A novel strategy to improve productivity through enhanced polyribosome assembly on the endoplasmic reticulum in CHO cells

In cell line development process, it is frequently observed that increased mRNA levels do not always correlate with protein expression levels in CHO cells. In line with this gap, the endoplasmic reticulum (ER) in CHO cells is much less proliferated as compared with that in terminally differentiated (i.e., professional) secretory cells, suggesting that there is still room to improve their specific productivity if translational efficiency on the ER can be up-regulated. Here we present a novel engineering approach (spERt Technology) to improve specific production rates by mimicking the ER translational apparatus of professional secretory cells. In spERt Technology, we exploit the unique factors that are required for translationally active polyribosome formation on the ER to directly enhance the translational efficiency (1, 2). A high antibody (Ab) producing clone generated by a novel screen using flow cytometry (3) was used as a model cell line. The factors were introduced into the high producer and a series of the spERt Technology - introduced cell lines were generated Among these cell lines, we selected one of the best clones (spERt-f9) having stable and high productivity. Polyribosome analysis of these cell lines revealed that enhanced assembly of the ER polyribosomes as expected (1). Consistent with the highly developed polyribosomes, the spERt-introduced cell lines produced higher levels of Ab than that of parental cells, and showed prominent increase of specific production rates. Further optimization of feeding process resulted in remarkable increase of productivity in spERt-f9 cells: Ab titers of 7.6 g/L and 9.5 g/L on day 14 and 17, respectively, were achieved in shake flask fed-batch cultures by using chemically defined media. Importantly, high cell viabilities were maintained in spERt-f9 cells throughout the culture periods. In addition, lower glucose consumption and reduced accumulation of ammonia were observed. Product quality in these cells were analyzed and compared with that in the parental cells. In conclusion, spERt Technology enables to improve productivity of high Ab producers, associated with reduced accumulation of waste metabolites and high cell viabilities

Chiral Symmetry and Heavy-Ion Collisions

I revisit the phase structure of hot and dense matter out of quarks and gluons with some historical consideration on the color deconfinement and chiral phase transitions. My goal is to make clear which part of the QCD phase diagram is under theoretical control and which part is not. I demonstrate that an uncommon but logically possible scenario other than the standard phase diagram cannot be ruled out. My emphasis is on the concern that one should correctly understand what kind of phenomenon occurs associated with the phase boundary line on the diagram. It is not quite obvious, in particular, where chiral symmetry restoration plays a phenomenological role in the temperature and baryon density plane except at the QCD (chiral) critical point.Comment: Plenary talk at Quark Matter 2008: 20th International Conference on Ultra-Relativistic Nucleus Nucleus Collisions (QM 2008), Jaipur, India, 4-10 Feb 200

Hydrodynamical analysis of hadronic spectra in the 130 GeV/nucleon Au+Au collisions

We study one-particle spectra and a two-particle correlation function in the 130 GeV/nucleon Au+Au collisions at RHIC by making use of a hydrodynamical model. We calculate the one-particle hadronic spectra and present the first analysis of Bose-Einstein correlation functions based on the numerical solution of the hydrodynamical equations which takes both longitudinal and transverse expansion into account appropriately. The hydrodynamical model provides excellent agreement with the experimental data in the pseudorapidity and the transverse momentum spectra of charged hadrons, the rapidity dependence of anti-proton to proton ratio, and almost consistent result for the pion Bose-Einstein correlation functions. Our numerical solution with simple freeze-out picture suggests the formation of the quark-gluon plasma with large volume and low net-baryon density.Comment: 7 pages, 8 figures, REVTeX4. Numerical results and figures are correcte

Inhibitory Effect of 1α-Hydroxyvitamin D3 on N-nitrosobis (2-oxopropyl)Amine-induced Cholangiocarcinogenesis in Syrian Hamsters

Sixty-three male 5-week-old Syrian hamsters received the carcinogen N-nitrosobis(2-oxopropyl)amine (BOP) s.c. in 5 weekly injections (the first, 70mg/kg body, and the remaining, 20mg/kg each). The hamsters that received BOP were given intragastric administration of 0.2ml of medium chain triglyceride (MCT) with or without 0.04μg of 1α-hydroxyvitamin D3 [1α(OH)D3] through a feeding tube for 12 weeks. Thus, 3 groups were assigned:Group 1;BOP alone (n＝20), Group 2;BOP＋MCT (n＝18) and Group 3;BOP＋1α(OH)D3 (n＝25). The mean body weight of Group 3 was lower than those of Groups 1 and 2 at the end of the experiment (p＜0.001,Tukey-Kramer HSD test). At the end of week 12, all surviving hamsters were put to sleep. The incidences of liver tumors were 80%, 72% and 32% in Groups 1, 2 and 3, respectively. The incidence of tumors in Group 3 was significantly lower than in Group 1 and Group 2 (p＜0.05, χ2-test). All tumors were cholangiocarcinoma. These results indicated that BOP-induced cholangiocarcinogenesis was suppressed by the supplemental administration of 1α(OH)D3

Gluteal-fold adipofascial perforator flap transposition for rectourethral fistula reconstruction

If a rectourinary fistula does not close spontaneously, it requires surgical closure. We present our experience of rectourethral fistula reconstruction using a gluteal-fold perforator flap, resulting in a successful outcome. The patient was a 64-year-old man with prostate cancer who underwent radical prostatectomy. However, he developed rectourinary fistula, which required surgical closure. A dissection was undertaken to divide the fistula tract, and the rectal and urethral defect were closed. A 12.0×3.0 cm gluteal-fold adipofascial perforator flap was harvested and placed in the space between the rectum and urethra. The viability of lap was favourable, without infection or necrosis. The patient could walk the next day, and was discharged 2 weeks later without fecaluria or liquid stool. We conclude that the gluteal-fold adipofascial perforator flap offers excellent functional advantages in rectourethral fistula reconstruction with minimal morbidity at the donor site