Arts of the Medieval Cathedrals: Studies on Architecture, Stained Glass, and Sculpture in Honor of Anne Prache

The touchstones of Gothic monumental art in France - the abbey church of Saint-Denis and the cathedrals of Chartres, Reims, and Bourges - form the core of this collection dedicated to the memory of Anne Prache. The essays reflect the impact of Prache’s career, both as a scholar of wide-ranging interests and as a builder of bridges between the French and American academic communities. Thus the authors include scholars in France and the United States, both academics and museum professionals, while the thematic matrix of the book, divided into architecture, stained glass, and sculpture, reflects the multiple media explored by Prache during her long career. The essays employ a varied range of methodologies to explore Gothic monuments. The chapters in the architectural section include an intensive archeological analysis of the foundations of Reims Cathedral, the close reading of a late medieval literary text for a symbolic understanding of Paris, and essays that explore the medieval use of practical geometry in designing entire buildings and their components. Saint-Denis, Reims, and Chartres, all monuments studied by Prache, are discussed in the next part, on stained glass. These chapters demonstrate how old problems can be clarified by new evidence, whether from the accessibility of previously unknown archival information, for Reims, or through revelations that arise from restoration, at Chartres. These essays also include a study showing the complexity of making attributions for the storied glass of Saint-Denis. The final set of essays likewise takes different approaches to sculpture, whether constructing links to the liturgy at Reims, or discussing the meaning of a sculptural ensemble studied by Prache early in her career, the cloister of Notre-Dame-en-Vaux in Châlons-en-Champagne, or scrupulously examining the façade sculpture at Bourges Cathedral for insights into the design process. As a whole, the volume provides a window onto key directions in the study of medieval monuments in the early twenty-first century and paint a picture of the vibrant scholarship that is Prache\u27s legacy.https://digitalcommons.hollins.edu/facbooks/1077/thumbnail.jp

Honoring the National Parks: A Local Adaptation of a Partners in the Parks Adventure

The National Collegiate Honors Council has long recognized that collaboration among institutions is important to honors education. Since its inception over five decades ago, NCHC has promoted the mutual exchange of ideas about honors in order to disseminate the best of these ideas as potential prototypes (Andrews). In addition to its annual NCHC conferences, which offer a large forum for sharing ideas, NCHC has fostered and supported a variety of collaborative programs such as Honors Semesters and Faculty Institutes, the most recent of which is the Partners in the Parks Program (PITP), which—like its predecessor programs—is designed not only to provide educational opportunities for students and faculty in honors but to inspire educational innovations within honors programs and colleges across the country. PITP has already begun to spin off such innovations. The adaptation of the PITP program “Fire Island to Ellis Island” in a college course called “Honoring the Parks” demonstrates the way that colleges and universities can use NCHC resources to inspire new educational opportunities on their campuses

Honoring the National Parks: A Local Adaptation of a Partners in the Parks Adventure

The National Collegiate Honors Council has long recognized that collaboration among institutions is important to honors education. Since its inception over five decades ago, NCHC has promoted the mutual exchange of ideas about honors in order to disseminate the best of these ideas as potential prototypes (Andrews). In addition to its annual NCHC conferences, which offer a large forum for sharing ideas, NCHC has fostered and supported a variety of collaborative programs such as Honors Semesters and Faculty Institutes, the most recent of which is the Partners in the Parks Program (PITP), which—like its predecessor programs—is designed not only to provide educational opportunities for students and faculty in honors but to inspire educational innovations within honors programs and colleges across the country. PITP has already begun to spin off such innovations. The adaptation of the PITP program “Fire Island to Ellis Island” in a college course called “Honoring the Parks” demonstrates the way that colleges and universities can use NCHC resources to inspire new educational opportunities on their campuses

IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals

Dendritic cells (DCs) are the professional APCs of the immune system, enabling T cells to perceive and respond appropriately to potentially dangerous microbes, while also being able to maintain T cell tolerance toward self. In part, such tolerance can be determined by IL-10 released from certain types of regulatory T cells. IL-10 has previously been shown to render DCs unable to activate T cells and it has been assumed that this process represents a general block in maturation. Using serial analysis of gene expression, we show that IL-10 pretreatment of murine bone marrow-derived DCs alone causes significant changes in gene expression. Furthermore, these cells retain the ability to respond to Toll-like receptor agonists, but in a manner skewed toward the selective induction of mediators known to enhance local inflammation and innate immunity, among which we highlight a novel CXCR2 ligand, DC inflammatory protein-1. These data suggest that, while the presence of a protolerogenic and purportedly anti-inflammatory agent such as IL-10 precludes DCs from acquiring their potential as initiators of adaptive immunity, their ability to act as initiators of innate immunity in response to Toll-like receptor signaling is enhanced