Comparison of Simulator Wear Measured by Gravimetric vs Optical Surface Methods for Two Million Cycles

Understanding wear mechanisms are key for better implants Critical to the success of the simulation Small amount of metal wear can have catastrophic effects in the patient such as heavy metal poisoning or deterioration of the bone/implant interface leading to implant failure Difficult to measure in heavy hard-on-hard implants (metal-on-metal or ceramic-on-ceramic) May have only fractions of a milligram of wear on a 200 g component At the limit of detection of even high-end balances when the component is 200 g and the change in weight is on the order of 0.000 1 grams Here we compare the standard gravimetric wear estimate with A non-contact 3D optical profiling method at each weighing stop A coordinate measuring machine (CMM) at the beginning and end of the ru

Exchange bias effect in the phase separated Nd_{1-x}Sr_{x}CoO_3 at the spontaneous ferromagnetic/ferrimagnetic interface

We report the new results of exchange bias effect in Nd_{1-x}Sr_{x}CoO_3 for x = 0.20 and 0.40, where the exchange bias phenomenon is involved with the ferrimagnetic (FI) state in a spontaneously phase separated system. The zero-field cooled magnetization exhibits the FI (T_{FI}) and ferromagnetic (T_C) transitions at ~ 23 and \sim 70 K, respectively for x = 0.20. The negative horizontal and positive vertical shifts of the magnetic hysteresis loops are observed when the system is cooled through T_{FI} in presence of a positive static magnetic field. Training effect is observed for x = 0.20, which could be interpreted by a spin configurational relaxation model. The unidirectional shifts of the hysteresis loops as a function of temperature exhibit the absence of exchange bias above T_{FI} for x = 0.20. The analysis of the cooling field dependence of exchange bias field and magnetization indicates that the ferromagnetic (FM) clusters consist of single magnetic domain with average size around \sim 20 and ~ 40 \AA ~ for x = 0.20 and 0.40, respectively. The sizes of the FM clusters are close to the percolation threshold for x = 0.20, which grow and coalesce to form the bigger size for x = 0.40 resulting in a weak exchange bias effect.Comment: 9 pages, 9 figure

Molecular characterization of pyridoxine 5′-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5′-phosphate oxidase deficiency (PNPOD; OMIM: 610090), an autosomal recessive inborn error of metabolism that usually manifests with neonatal-onset severe seizures and subsequent encephalopathy. At present, 27 pathogenic mutations of the gene encoding human PNPO are known, 13 of which are homozygous missense mutations; however, only 3 of them have been characterised with respect to the molecular and functional properties of the variant enzyme forms. Moreover, studies on wild type and variant human PNPOs have so far largely ignored the regulation properties of this enzyme. Here, we present a detailed characterisation of the inhibition mechanism of PNPO by pyridoxal 5′-phosphate (PLP), the reaction product of the enzyme. Our study reveals that human PNPO has an allosteric PLP binding site that plays a crucial role in the enzyme regulation and therefore in the regulation of vitamin B6 metabolism in humans. Furthermore, we have produced, recombinantly expressed and characterised several PNPO pathogenic variants responsible for PNPOD (G118R, R141C, R225H, R116Q/R225H, and X262Q). Such replacements mainly affect the catalytic activity of PNPO and binding of the enzyme substrate and FMN cofactor, leaving the allosteric properties unaltered

The extent of non tariff barriers to industrial countries' imports

This paper examines the extent of non-tariffs barriers to sixteen industrial countries' imports. Using three alternative measures it shows that governmental commodity-specific border-measures affect 27% of all imports and over 34% of imports from developing countries. It also shows that during the period 1981-1983,NTBs became significantly more extensive. Detailed statistics reveal considerable variations in NTB coverage by commodity, type of barrier, importer and exporter. The data on which these conclusions are based are compiled from official information at the finest level of disaggregation; they are described in the paper

The extent of non tariff barriers to industrial countries' imports

This paper examines the extent of non-tariffs barriers to sixteen industrial countries' imports. Using three alternative measures it shows that governmental commodity-specific border-measures affect 27% of all imports and over 34% of imports from developing countries. It also shows that during the period 1981-1983,NTBs became significantly more extensive. Detailed statistics reveal considerable variations in NTB coverage by commodity, type of barrier, importer and exporter. The data on which these conclusions are based are compiled from official information at the finest level of disaggregation; they are described in the paper

Discrete Wigner functions and the phase space representation of quantum teleportation

We present a phase space description of the process of quantum teleportation for a system with an $N$ dimensional space of states. For this purpose we define a discrete Wigner function which is a minor variation of previously existing ones. This function is useful to represent composite quantum system in phase space and to analyze situations where entanglement between subsystems is relevant (dimensionality of the space of states of each subsystem is arbitrary). We also describe how a direct tomographic measurement of this Wigner function can be performed.Comment: 8 pages, 1 figure, to appear in Phys Rev

Test of quantum nonlocality for cavity fields

There have been studies on formation of quantum-nonlocal states in spatially separate two cavities. We suggest a nonlocal test for the field prepared in the two cavities. We couple classical driving fields with the cavities where a nonlocal state is prepared. Two independent two-level atoms are then sent through respective cavities to interact off-resonantly with the cavity fields. The atomic states are measured after the interaction. Bell's inequality can be tested by the joint probabilities of two-level atoms being in their excited or ground states. We find that quantum nonlocality can also be tested using a single atom sequentially interacting with the two cavities. Potential experimental errors are also considered. We show that with the present experimental condition of 5% error in the atomic velocity distribution, the violation of Bell's inequality can be measured.Comment: 14pages, 2figures. accepted to Phys. Rev.

Thermal excitation of heavy nuclei with 5-15 GeV/c antiproton, proton and pion beams

Excitation-energy distributions have been derived from measurements of 5.0-14.6 GeV/c antiproton, proton and pion reactions with $^{197}$Au target nuclei, using the ISiS 4$\pi$ detector array. The maximum probability for producing high excitation-energy events is found for the antiproton beam relative to other hadrons, $^3$He and $\bar{p}$ beams from LEAR. For protons and pions, the excitation-energy distributions are nearly independent of hadron type and beam momentum above about 8 GeV/c. The excitation energy enhancement for $\bar{p}$ beams and the saturation effect are qualitatively consistent with intranuclear cascade code predictions. For all systems studied, maximum cluster sizes are observed for residues with E*/A $\sim$ 6 MeV.Comment: 14 pages including 5 figures and 1 table. Accepted in Physics Letter B. also available at http://nuchem.iucf.indiana.edu

Optical realization of universal quantum cloning

Beyond the no-cloning theorem, the universal symmetric quantum cloning machine was first addressed by Buzek and Hillery. Here, we realized the one-to-two qubits Buzek-Hillery cloning machine with linear optical devices. This method relies on the representation of several qubits by a single photon. We showed that, the fidelities between the two output qubits and the original qubit are both 5/6 (which proved to be the optimal fidelity of one-to-two qubits universal cloner) for arbitrary input pure states.Comment: 5 Pages, 2 Figure

Single-photon tunneling

Strong evidence of a single-photon tunneling effect, a direct analog of single-electron tunneling, has been obtained in the measurements of light tunneling through individual subwavelength pinholes in a thick gold film covered with a layer of polydiacetylene. The transmission of some pinholes reached saturation because of the optical nonlinearity of polydiacetylene at a very low light intensity of a few thousands photons per second. This result is explained theoretically in terms of "photon blockade", similar to the Coulomb blockade phenomenon observed in single-electron tunneling experiments. The single-photon tunneling effect may find many applications in the emerging fields of quantum communication and information processing.Comment: 4 pages, 4figure