97 research outputs found

    UNKNOTTABILITY OF SPATIAL GRAPHS BY REGION CROSSING CHANGES

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    A region crossing change is a local transformation on spatial graph diagrams switching the over/under relation at all the crossings on the boundary of a region. In this paper, we show that a spatial graph of a planar graph is unknottable by region crossing changes if and only if the spatial graph is non-Eulerian or is Eulerian and proper

    Face sizes and the connectivity of the dual

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    For each c1c\ge 1 we prove tight lower bounds on face sizes that must be present to allow 11- or 22-cuts in simple duals of cc-connected maps. Using these bounds, we determine the smallest genus on which a cc-connected map can have a simple dual with a 22-cut and give lower and some upper bounds for the smallest genus on which a cc-connected map can have a simple dual with a 11-cut.Comment: 19 pages, 11 figure

    Cancer gene expression database (CGED): a database for gene expression profiling with accompanying clinical information of human cancer tissues

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    Gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as developments of new methods of diagnosis and therapy. Our collaborative efforts in Japan have been mainly focused on solid tumors such as breast, colorectal and hepatocellular cancers. The expression data are obtained by a high-throughput RT–PCR technique, and patients are recruited mainly from a single hospital. In the cancer gene expression database (CGED), the expression and clinical data are presented in a way useful for scientists interested in specific genes or biological functions. The data can be retrieved either by gene identifiers or by functional categories defined by Gene Ontology terms or the Swiss-Prot annotation. Expression patterns of multiple genes, selected by names or similarity search of the patterns, can be compared. Visual presentation of the data with sorting function enables users to easily recognize of relationships between gene expression and clinical parameters. Data for other cancers such as lung and thyroid cancers will be added in the near future. The URL of CGED is http://cged.hgc.jp

    The effect of omega-3 fatty acids on psychophysiological assessment for the secondary prevention of posttraumatic stress disorder: an open-label pilot study.

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    Our recent pilot study has shown that the supplementation of omega-3 fatty acids (fish oil) immediately after a traumatic event may be effective toward the secondary prevention of post-traumatic disorder (PTSD). To lay the groundwork for addressing the mechanism by which omega-3 fatty acids can prevent PTSD, we analyzed its psychophysiological data. The psychophysiological data included heart rate, skin conductance, and continuous blood pressure during patient subjection to startling tones and idiographic trauma-related cues. Of the 8 patients, 1 met the diagnostic criteria for PTSD. Compared to the seven patients without PTSD, one patient with PTSD showed relatively large reactivity to the startle tones. In contrast, this patient did not show large reactivity to the trauma-related cue during script-driven imagery. The combination of psychophysiological measurements in our randomized control trial should shed light on the underlying mechanisms by which omega-3 fatty acids can prevent PTSD
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