Timeline of experiment.

<p>Timeline of experiment.</p

GCP II inhibition did not significantly affect weight loss induced by pyridoxine.

<p>Weights were measured every day of the study. A significant difference was observed between the controls and both the pyridoxine treated groups (p<0.05); no difference was observed between the pyridoxine/vehicle and pyridoxine/2-MPPA groups (p>0.05). N = 10/group. Data = mean ± SEM. * = p<0.05.</p

GCP II inhibition improves hot plate reaction times.

<p>Pyridoxine intoxication increased reaction time on the hot plate, which was improved by GCP II on days 18–25. By day 29, both of the pyridoxine treated groups had recovered to control levels. N = 10/group. Data = mean ± SEM. * = p<0.05.</p