271 research outputs found
Cognitive Behavior Therapy and Mindfulness-Based Intervention for Social Anxiety Disorder
Social anxiety disorder (SAD) is a marked, or intense, fear or anxiety of social situations in which the individual may be scrutinized by others. The most well-known and efficacious psychological treatment for individuals with SAD is cognitive behavior therapy (CBT). Previous meta-analysis reported that the most recommended treatment components of CBT programs for SAD are exposure and cognitive restructuring. In recent years, mindfulness-based intervention (MBI) has shown efficacy in improving SAD. In this chapter, exposure treatment and cognitive restructuring for SAD and MBI for SAD are introduced. Additionally, the benefits of using MBI for SAD are discussed. This chapter also discusses the effects on the improvement of trait-mindfulness for social anxiety. Finally, we indicate the possibilities of the combination of mindfulness and exposure for treatment of SAD
Effects of Geometry on Intensity of Singular Stress Fields at the Corner of Single-Lap Joints
This paper discusses effects of adhesive thickness, overlap length and material combinations on the single-lap joints strength from the point of singular stress fields. A useful method calculating the ratio of intensity of singular stress is proposed using FEM for different adhesive thickness and overlap length. It is found that the intensity of singular stress increases with increasing adhesive thickness, and decreases with increasing overlap length. The increment and decrement are different depending on material combinations between adhesive and adherent.WASET 2011:INTERNATIONAL CONFERENCE PROGRAM Holiday Inn Paris Montparnesse-Avenue du Maine, June 24-26, 2011, Paris, Franc
Extension of measurement range in OCDR based on double-modulation scheme
We extend the measurement range of optical correlation-domain reflectometry
(OCDR) by modulating the laser output frequency at two frequencies, while
preserving spatial resolution. We demonstrate distributed reflectivity sensing
with a ten-fold extended measurement range.Comment: 4 pages, 6 figure
Observation of Rayleigh scattering by simplified optical correlation-domain reflectometry without frequency shifter
We present a method for measuring the transmission loss of an optical fiber
using simplified optical correlation-domain reflectometry. By intentionally
lowering the spatial resolution of the system, we observe the Rayleigh
scattered signal for the first time without the need for a frequency shifter.
Using this method, we simultaneously measure the transmission loss, location,
and loss of faulty connections along a 10-km-long fiber under test by
performing distributed reflected-power measurements of Rayleigh scattering and
Fresnel reflection
Conveyance of texture signals along a rat whisker
Neuronal activities underlying a percept are constrained by the physics of sensory signals. In the tactile sense such constraints are frictional stick–slip events, occurring, amongst other vibrotactile features, when tactile sensors are in contact with objects. We reveal new biomechanical phenomena about the transmission of these microNewton forces at the tip of a rat’s whisker, where they occur, to the base where they engage primary afferents. Using high resolution videography and accurate measurement of axial and normal forces at the follicle, we show that the conical and curved rat whisker acts as a sign-converting amplification filter for moment to robustly engage primary afferents. Furthermore, we present a model based on geometrically nonlinear Cosserat rod theory and a friction model that recreates the observed whole-beam whisker dynamics. The model quantifies the relation between kinematics (positions and velocities) and dynamic variables (forces and moments). Thus, only videographic assessment of acceleration is required to estimate forces and moments measured by the primary afferents. Our study highlights how sensory systems deal with complex physical constraints of perceptual targets and sensors
Elevation of Bombina variegata peptide 8 in mice with collagen-induced arthritis
<p>Abstract</p> <p>Background</p> <p><it>Bombina variegate </it>peptide 8 (Bv8) is a small protein secreted by frog skin. Recently it has been shown to contribute to tumor angiogenesis in mouse model. The purpose of this study was to investigate Bv8 in mice with type II collagen-induced arthritis (CIA).</p> <p>Methods</p> <p>We induced CIA in male DBA/1J mice. The severity of arthritis was evaluated based on an arthritis score. RNA was extracted from the joint, and examined for Bv8 mRNA expression by RT-PCR and real-time RT-PCR. Synovial tissue and bone marrow were immunohistochemically examined using anti-Bv8 antibody.</p> <p>Results</p> <p>The level of Bv8 mRNA expression in the joint was below the detection limit in the control group, but was elevated in the CIA group, and was correlated with the arthritis score. In addition, an increase in Bv8-positive cells was observed in the synovium and bone marrow in the CIA group.</p> <p>Conclusion</p> <p>Bv8 was elevated in the synovium and bone marrow of CIA mice, suggesting that Bv8 plays an important role in the pathogenesis of arthritis.</p
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