2 research outputs found
Antibacterial and cytotoxic activity of Kenyan medicinal plants
Seven medicinal plant extracts traditionally used in Kenya, mainly for
management of infectious conditions, were chosen and screened for their
antibacterial activity against Gram-negative ( Pseudomonas aeruginosa
and Escherichia coli ) and Gram-positive ( Bacillus cereus and
Staphylococcus aureus ) bacteria. Antibacterial activity was tested
using the broth dilution method. Harrisonia abyssinica and Terminalia
kilimandscharica extracts showed significant activity against Gram+
and Gram- bacteria. The methanolic extracts of T. kilimandscharica bark
and H. abyssinica bark and leaves showed minimum inhibitory activity
against all tested bacteria, with minimal inhibitory concentrations
ranging from 25-150 mg/mL. Ajuga remota and Amaranthus hybridus ,
which are lethal to brine shrimp nauplii, showed significantly lower
antibacterial activity than those that were relatively non-toxic