Chelates of Cu(II), Ni(II) & Co(II) with 3,5-Dimethylpyrazole-I-acetic Acid

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Thickness dependent studies of hetero-junction solar cell synthesized on quartz substrate by spray pyrolysis technique

36-43Variable thickness hetero-junction solar cells synthesized on quartz substrate by spray pyrolysis technique synthesized quartz based solar cells have been found to possess cell parameters such as open circuit voltage, saturation current density, fill factor and efficiency in the range of 191 – 449 mV, 2×10-9 – 0.11×10-6 A cm-2, 15 – 20 % and 0.2×10-9 – 3.35×10-6 % at 206 mW/cm2 (at air mass 5.6), respectively. Series and shunt resistance of the solar cells have been found to vary with the thickness of semiconductor films. Thick film solar cells are found to possess reasonably good cell parameters compared to thin film solar cells due to enhancement of charge concentration, mobility, grain size, variation of optical band gap, excesses atomic percentage of Ti, Cu, Te, Sn elements in TiO2, CuO, CdTe, SnS films and less structural defects, increment of activation energy as well as existence of mixed phase at the Schottky barrier. The optical response of hetero-junction solar cells is found to be thickness dependent. Good rectifying characteristic has been reported in the present work for both thick and thin hetero-junction solar cells. All the measurements have been performed in air without protection against oxygen gas or moisture, which shows the stability of spray pyrolyzed thin films

Evaluating the Expression of Candidate Homeobox Genes and Their Role in Local-Site Inflammation in Mucosal Tissue Obtained from Children with Non-Syndromic Cleft Lip and Palate

Funding Information: Funding: The present study was funded by Riga Stradinš University (RSU). Funding Information: The present study was funded by Riga Stradin? University (RSU).We would like to extend our gratitude to Ilze Akota, Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, RSU for providing the patient material. We would also like to acknowledge the parents of the patients for consenting to participate in the present study. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Craniofacial development including palatogenesis is a complex process which requires an orchestrated and spatiotemporal expression of various genes and factors for proper embryogenesis and organogenesis. One such group of genes essential for craniofacial development is the homeobox genes, transcriptional factors that are commonly associated with congenital abnormalities. Amongst these genes, DLX4, HOXB3, and MSX2 have been recently shown to be involved in the etiology of non-syndromic cleft lip and palate. Hence, we investigated the gene and protein expression of these genes in normal and cleft affected mucosal tissue obtained from 22 children, along with analyzing their role in promoting local-site inflammation using NF-κB. Additionally, we investigated the role of PTX3, which plays a critical role in tissue remodeling and wound repair. We found a residual gene and protein expression of DLX4 in cleft mucosa, although no differences in gene expression levels of HOXB3 and MSX2 were noted. However, a significant increase in protein expression for these genes was noted in the cleft mucosa (p < 0.05), indicating increased cellular proliferation. This was coupled with a significant increase in NF-κB protein expression in cleft mucosa (p < 0.05), highlighting the role of these genes in promotion of pro-inflammatory environment. Finally, no differences in gene expression of PTX3 were noted.publishersversionPeer reviewe

Debunking the myth of using “quiet” in clinical departments : an integrative overview of available literature

Funding Information: We would like to acknowledge the support and contributions of The ECOMSIR Collaborative (European Collaboration of Medical Students in Research), a non-profit, non-governmental student collaboration. The support of Riga Stradins University (RSU) is also greatly acknowledged.publishersversionPeer reviewe

Study of maternal and perinatal outcome in cases of a HELLP syndrome

Background: HELLP is an acronym which describes the presence of haemolysis, elevated liver enzymes, low platelet count during pregnancy. It is a life-threatening manifestation of pre-eclampsia. The incidence of HELLP syndrome is 0.5-0.9% of all pregnancies and 10-20% in cases of pre-eclampsia. The rationale of this study lied in the anticipation that knowledge of incidence of the HELLP Syndrome will incite the interest of medical fraternity handling various pregnancy related complication. The results may also imply that early detection of high-risk individuals by primary medical personnel and timely referral to a tertiary care centre will be helpful in improving maternal and perinatal outcomes. Aim of this study were to study the incidence of HELLP syndrome in patients with pre-eclampsia and to study maternal and perinatal outcome in pre-eclampsia patients complicated with HELLP syndrome. Methods: A prospective observational study of 400 admitted cases with more than 20 weeks of gestation having pre-eclampsia. Statistical analysis of the data done on IBM SPSS Statistics Version. Results: The incidence of HELLP syndrome in pre-eclampsia was found to be 9.25%. The major maternal complications were placental abruption (35.14%), acute renal failure (16.22%), eclampsia (5.4%), papilledema (5.41%), PRES (5.41%), DIC (5.41%), maternal mortality (8.11%) in cases of HELLP syndrome while low birth weight (48.64%) respiratory distress syndrome (35.14%), meconium aspiration syndrome (18.9%), IUD (10.81%), NICU admission (37.84%), NND (10.81%) were neonatal complications. Conclusions: HELLP syndrome in pre-eclampsia is associated with significant maternal and perinatal morbidity and mortality and early detection and prompt management is the key for a better maternal and perinatal outcome

The new face of monkeypox virus : an emerging global emergency

publishersversio

Massive apoptosis of bone marrow cells in aplastic anaemia

This article does not have an abstract

Group A streptococcal (GAS) infections amongst children in Europe : Taming the rising tide

A rising tide of Group A streptococcal infections is being reported in several European countries including the UK, Spain, Sweden, France, and Ireland. In this editorial, we shed light on the current scenario and present the discussion on the latest available interim clinical guidelines. We further explore the cause of this sudden rise and the interventional measures needed to tame the rising tide.publishersversio

Fostering Public Health Ethics Awareness among Medical Students through Interactive Web-Based Values Exchange Learning : A Cross-Sectional Study

Background Medical ethics have traditionally encountered resistance in medical education, with doubts regarding their necessity during preclinical years. Concerns include the practical application of theoretical ethics and favoring the learning of ethics through observation and imitation. Furthermore, ethics courses often focus on codes and regulations and neglect the promotion of moral reasoning and decision-making skills. Therefore, enhancing ethical researcher-training modules is essential for advancing instructional methods and promoting a unified and interactive learning atmosphere. Methods A three-week course was conducted using the Values Exchange (VX) online platform to assess the effectiveness of the VX system in involving students and its impact on their perceptions of the importance of research ethics. Accordingly, a blended course was provided as an optional course to the students, and a qualitative course evaluation survey was administered at the end of the course. Results Sixty-one medical students participated in a pilot-blended research ethics program and the majority (93%) reported a positive learning experience. The course was preferred over traditional classroom-based courses by 80% of the respondents, with 77% reporting increased interest and motivation to study Research Ethics. Over half of the students (57%) reported that the course stimulated their thinking and changed their perspectives on handling medical research issues. Many students (20%) reported improvements in their social and information technology skills. The VX platform was able to meet the expectations of both faculty and students, and fulfilled all dimensions of the Health Professions Learning Environment Conceptual Framework. Conclusions The VX platform provides an interactive and effective simulated learning environment that promotes ethical research Aligned with the Health Professions Learning Environment Framework, VX fosters core competencies, such as ethical reasoning, decision-making, and cultural respect. Medical schools are encouraged to implement VX to enhance the teaching of research ethics.Peer reviewe