4,550 research outputs found
Brane-worlds and theta-vacua
Reductions from odd to even dimensionalities ( or ), for
which the effective low-energy theory contains chiral fermions, present us with
a mismatch between ultraviolet and infrared anomalies. This applies to both
local (gauge) and global currents; here we consider the latter case. We show
that the mismatch can be explained by taking into account a change in the
spectral asymmetry of the massive modes--an odd-dimensional analog of the
phenomenon described by the Atiyah-Patodi-Singer theorem in even
dimensionalities. The result has phenomenological implications: we present a
scenario in which a QCD-like -angle relaxes to zero on a certain
(possibly, cosmological) timescale, despite the absence of any light axion-like
particle.Comment: 44 pages, 4 figure
Basic Education in Cambodia: The Impact of UNESCO onPolicies in the 1990s
Efforts to enhance opportunities for Basic Education have been growing within many developing nations after the1990 World Conference on Education For All (WCEFA) in Jomtien, Thailand. In the face of political turmoil, financial constraint and social insecurity, Cambodia with the encouragement and assistance of the United Nations Educational, Scientific, and Cultural Organization (UNESCO), took measures to increase educational opportunities for all her citizens through Basic Education strategic plans and pledged to eradicate illiteracy by the year 2000. This article examines the joint efforts during the 1990s of this organization as a key assistance and support UN agency for educational policy and strategy formulations, and the Cambodian government as a national agency for educational initiatives and implementation. UNESCO’s inputs for policy implementation are also detailed to evaluate the overall impact of the organization during the last decade. Analyses are based primarily on interviews with some key government policymakers, fieldwork observation and interviews with school-aged children, several speeches of top government officials, and existing related official education statistics and indicators in Cambodia
Web-based Decision Support System for Rural Land Use Planning-WebLUP-a Prototype
Rosana G. Moreira, Editor-in-Chief; Texas A&M UniversityThis is a paper from International Commission of Agricultural Engineering (CIGR, Commission Internationale du Genie Rural) E-Journal Volume 8 (2006): Web-based Decision Support System for Rural Land Use Planning-WebLUP-a Prototype. Manuscript IT 05 005. Vol. VIII. March, 2006
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells. N-Acetyllactosamine-containing glycans, known as galectin ligands, were found enriched in detergent-resistant membranes. Here, we analyzed the potential contribution of N-and/ or O-glycans in this mechanism. Structural studies were carried out on the brush border membrane-enriched fraction using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and nano-ESI-QTOF-MS/MS. The pattern of N-glycans was very heterogeneous, with the presence of high mannose- and hybrid-type glycans as well as a multitude of complex-type glycans. In contrast, the pattern of O-glycans was very simple with the presence of two major core type 1 O-glycans, sialylated and bisialylated T-antigen structures {[}Neu5Ac alpha 2-3Gal beta 1-3GalNAc-ol and Neu5Ac alpha 2-3Gal beta 1 -3(Neu5Ac alpha 2-6)GalNAc-ol]. Thus, N-glycans rather than O-glycans contain the N-acetyllactosamine recognition signals for the lipid raft-based galectin-4-dependent apical delivery. In the presence of 1-deoxymannojirimycin, a drug which inhibits the generation of hybrid-type or complex type N-glycans, the extensively O-glycosylated mucin-like MUC1 glycoprotein was not delivered to the apical brush border but accumulated inside the cells. Altogether, our data demonstrate the crucial role of complex N-glycans in the galectin-4-dependent delivery of glycoproteins to the apical brush border membrane of enterocytic HT-29 cells
Increasing the Reliability of Adaptive Quadrature Using Explicit Interpolants
We present two new adaptive quadrature routines. Both routines differ from
previously published algorithms in many aspects, most significantly in how they
represent the integrand, how they treat non-numerical values of the integrand,
how they deal with improper divergent integrals and how they estimate the
integration error. The main focus of these improvements is to increase the
reliability of the algorithms without significantly impacting their efficiency.
Both algorithms are implemented in Matlab and tested using both the "families"
suggested by Lyness and Kaganove and the battery test used by Gander and
Gautschi and Kahaner. They are shown to be more reliable, albeit in some cases
less efficient, than other commonly-used adaptive integrators.Comment: 32 pages, submitted to ACM Transactions on Mathematical Softwar
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