Change in the cell size.

<p>The size change is shown after treatment with cytochalasin B relative to the control (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0122774#pone.0122774.g006" target="_blank">Fig. 6</a>).</p

The average size of cells as a function of <i>in vitro</i> aging with continued passage.

<p>Results for cells without (control) and with the treatment with cytochalasin B are shown. Each “variability” bar corresponds to one standard deviation.</p

Representative images of cells collected in the Hoffman contrast mode. Images before (left) and after (right) cytochalasin B treatment for passages 2 (a,b) and 6 (c,d).

<p>Representative images of cells collected in the Hoffman contrast mode. Images before (left) and after (right) cytochalasin B treatment for passages 2 (a,b) and 6 (c,d).</p

Example of cross-section of mouse skin.

<p>(c,d) mice #2 and (a,b) mice # 4. (a,c) Cytochalasin-treated skin; (b,d) The side treated with placebo. The scale bar is 100 microns.</p

Number of cells per a definite area.

<p>The average numbers of cells within 10x10 micron^2 area as well as one standard deviation.</p

Representative confocal images of epithelial cells of mouse skin.

<p>Skin is shown treated with cytochalasin B (left) and with placebo (right). Skin samples of mouse #2 (a,b), 5 (c,d), and 1 (e,f) are shown.</p