Results for the <i>in vivo</i> cervix study.

<p>Boxplots for (A) full spectral Monte Carlo extracted and (B) ratiometrically (584/545) extracted [THb]. Unpaired two-sided student <i>t</i>-tests were performed between normal, CIN1, and CIN2+. Significant <i>p</i>-values are shown.</p

Wavelengths used for extraction of [THb] and SO₂.

<p>Wavelengths used for extraction of [THb] and SO₂.</p

Correlation between Monte Carlo analysis and ratiometric analysis.

<p>(A) Correlation coefficients between the full spectral Monte Carlo and ratiometrically extracted [THb] as a function of the average full spectral Monte Carlo extracted [THb] for the 9 tissue groups in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082977#pone-0082977-t004" target="_blank">Table 4</a>. (B) Correlation coefficients between the full spectral Monte Carlo and ratiometrically extracted SO₂ as a function of the average full spectral Monte Carlo extracted [THb] for the 9 tissue groups in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082977#pone-0082977-t004" target="_blank">Table 4</a>.</p

Optical properties for simulated and experimental tissue-mimicking phantoms.

<p>Optical properties for simulated and experimental tissue-mimicking phantoms.</p

Results for the <i>in vivo</i> head and neck study.

<p>Boxplots for SO₂ at malignant and normal sites extracted with the (A) full spectral Monte Carlo analysis and the (B) ratiometric analysis. Wilcoxon rank-sum tests were performed between normal and SCC sites for each tissue type. Significant <i>p</i>-values from are shown. (SCC: squamous cell carcinoma).</p

The area under the receiver operating curves computed from the logistic regression model built base on different optical biomarkers from the full spectral MC and the ratiometric analyses.

<p>The area under the receiver operating curves computed from the logistic regression model built base on different optical biomarkers from the full spectral MC and the ratiometric analyses.</p