73 research outputs found
Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti
Bianchi type-I cosmological model in Lyra\u27s manifold is obtained assuming a massless scalar field as the source of gravitational field. Some physical and geometrical properties of the model are discussed.Razvili smo Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti kada je izvor gravitacijskog polja bezmaseno skalarno polje. Raspravljaju se neka fizička i geometrijska svojstva modela
Evaluation of Salinity Problem in Swell-Shrink Soils of a Part of the Purna Valley, Maharashtra
Abstract: The study on evaluatation of salinity problem in swell-shrink soils (Vertisols
Spin and charge ordering in self-doped Mott insulators
We have investigated possible spin and charge ordered states in 3d
transition-metal oxides with small or negative charge-transfer energy, which
can be regarded as self-doped Mott insulators, using Hartree-Fock calculations
on d-p-type lattice models. It was found that an antiferromagnetic state with
charge ordering in oxygen 2p orbitals is favored for relatively large
charge-transfer energy and may be relevant for PrNiO and NdNiO. On the
other hand, an antiferromagnetic state with charge ordering in transition-metal
3 orbitals tends to be stable for highly negative charge-transfer energy and
can be stabilized by the breathing-type lattice distortion; this is probably
realized in YNiO.Comment: 4 pages, 4 figure
Electronic structure of NiS_{1-x}Se_x
We investigate the electronic structure of the metallic NiSSe
system using various electron spectroscopic techniques. The band structure
results do not describe the details of the spectral features in the
experimental spectrum, even for this paramagnetic metallic phase. However, a
parameterized many-body multi-band model is found to be successful in
describing the Ni~2 core level and valence band, within the same model. The
asymmetric line shape as well as the weak intensity feature in the Ni~2 core
level spectrum has been ascribed to extrinsic loss processes in the system. The
presence of satellite features in the valence band spectrum shows the existence
of the lower Hubbard band, deep inside the metallic regime, consistent
with the predictions of the dynamical mean field theory.Comment: To be published in Physical Review B, 18 pages and 5 figure
Isoniazid hair concentrations in children with tuberculosis: a proof of concept study
Assessing treatment adherence and quantifying tuberculosis drug exposure among children is challenging. We undertook a “proof of concept” study to assess the drug concentrations of isoniazid in hair as a therapeutic drug monitoring tool. Children <12 years of age initiated on thrice-weekly treatment including isoniazid (10 mg/kg) for newly diagnosed tuberculosis were enrolled. Isoniazid concentrations in hair were measured using liquid chromatography-tandem mass spectrometry at 1, 2, 4 and 6 months after tuberculosis treatment initiation. We found that isoniazid hair concentrations in all children on thrice weekly isoniazid were detectable and displayed variability across a dynamic range
Georeferenced soil information system: assessment of database
Land-use planning is a decision-making process that
facilitates the allocation of land to different uses that
provide optimal and sustainable benefit. As land-use
is shaped by society–nature interaction, in land-use
planning different components/facets play a significant
role involving soil, water, climate, animal (ruminant/
non-ruminant) and others, including forestry
and the environment needed for survival of mankind.
At times these components are moderated by human
interference. Thus land-use planning being a dynamic
phenomenon is not guided by a single factor, but by a
complex system working simultaneously,which largely
affects the sustainability. To address such issues a
National Agricultural Innovation Project (NAIP) on
‘Georeferenced soil information system for land-use
planning and monitoring soil and land quality for
agriculture’ was undertaken to develop threshold
values of land quality parameters for land-use planning
through quantitative land evaluation and crop
modelling for dominant cropping systems in major
agro-ecological sub-regions (AESRs) representing
rice–wheat cropping system in the Indo-Gangetic
Plains (IGP) and deep-rooted crops in the black
soil regions (BSR). To assess the impact of landuse
change, threshold land quality indicator values
are used. A modified AESR map for agricultural landuse
planning is generated for effective land-use planning
Soil information system: use and potentials in humid and semi-arid tropics
The articles presented in this special section emanated from the researches of consortium members of the National Agricultural Innovative Project (NAIP, Component 4) of the Indian Council of Agricultural Research (ICAR), New Delhi. These researches have helped develop a soil information system (SIS). In view of the changing scenario all over the world, the need of the hour is to get assistance from a host of researchers specialized in soils, crops, geology, geography and information technology to make proper use of the datasets. Equipped with the essential knowledge of data storage and retrieval for management recommendations, these experts should be able to address the issues of land degradation, biodiversity, food security, climate change and ultimately arrive at an appropriate agricultural land-use planning. Moreover, as the natural resource information is an essential prerequisite for monitoring and predicting global environmental change with special reference to climate and land use options, the SIS needs to be a dynamic exercise to accommodate temporal datasets, so that subsequently it should result in the evolution of the soil information technology. The database developed through this NAIP would serve as an example of the usefulness of the Consortium and the research initiative of ICAR involving experts from different fields to find out the potentials of the soils of humid and semi-arid bioclimatic systems of the country
Randomized Clinical Trial of High-Dose Rifampicin With or Without Levofloxacin Versus Standard of Care for Pediatric Tuberculous Meningitis: The TBM-KIDS Trial
Background. Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains unclear. There have been no antimicrobial treatment trials for pediatric TBM.
Methods. TBM-KIDS was a phase 2 open-label randomized trial among children with TBM in India and Malawi. Participants received isoniazid and pyrazinamide plus: (i) high-dose rifampicin (30 mg/kg) and ethambutol (R30HZE, arm 1); (ii) high-dose rifampicin
and levofloxacin (R30HZL, arm 2); or (iii) standard-dose rifampicin and ethambutol (R15HZE, arm 3) for 8 weeks, followed by 10 months of standard treatment. Functional and neurocognitive outcomes were measured longitudinally using Modified Rankin Scale (MRS) and Mullen Scales of Early Learning (MSEL).
Results. Of 2487 children prescreened, 79 were screened and 37 enrolled. Median age was 72 months; 49%, 43%, and 8% had stage I, II, and III disease, respectively. Grade 3 or higher adverse events occurred in 58%, 55%, and 36% of children in arms 1, 2, and 3, with 1 death (arm 1) and 6 early treatment discontinuations (4 in arm 1, 1 each in arms 2 and 3). By week 8, all children recovered to MRS score of 0 or 1. Average MSEL scores were significantly better in arm 1 than arm 3 in fine motor, receptive language, and expressive language domains (P < .01).
Conclusions. In a pediatric TBM trial, functional outcomes were excellent overall. The trend toward higher frequency of adverse events but better neurocognitive outcomes in children receiving high-dose rifampicin requires confirmation in a larger trial.
Clinical Trials Registration. NCT02958709
Airflow resistance in soybean
Resistance of material to airflow is an important factor to consider in the design of a dryer or an aeration system. The airflow resistance of soybean was determined with the modified airflow resistance apparatus. It was found that pressure drop increased with increase in airflow rate, bulk density, bed depth and decreased with moisture content. Modified Shedd equation, Hukill and Ives equation and modified Ergun equation were examined for pressure drop prediction. Airflow resistance was accurately described by modified Shedd equation followed by Hukill and Ives equation and modified Ergun equation. The developed statistical model comprised of airflow rate, moisture content and bulk density could fit pressure drop data reasonably well
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