6 research outputs found

    Context server on a mobile device

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    Da bi mobilne aplikacije lahko učinkovito nudile vse svoje storitev in jih prilagodile uporabniku, bi morale pri tem uporabiti ves kontekst uporabnika in njegove okolice. V obstoječih raziskavah to nalogo prevzema poseben kontekstni strežnik, ki skrbi za zbiranje podatkov ter posredovanje informacij aplikaciji. V primeru, da bi tak kontekstni strežnik deloval na mobilni napravi, bi bila postopoma odpravljena potreba po omenjenem sistemu. V sklopu naloge smo predlagani model kontekstnega strežnika uspešno implementirali in njegovo delovanje preizkusili s pomočjo kontekstno odvisne aplikacije, ki deluje na principu tekstovne klasifikacije uporabnikovih vnosov v spletnih iskalnikih in njegovi trenutni lokaciji. Aplikaciji omenjenih podatkov ni potrebno zajeti ročno, saj so ti ob pojavitvi novega podatka avtomatično posredovani preko kontekstnega strežnika.In order for mobile applications to efficiently offer all of their services and adjust them according to the end user, they would need to monitor all of his context and surroundings. In the existing researches this is done by a special context server which is responsible for data retrieval and transmission of information application. In the event, when the context server would work on a mobile device, the before mentioned system would gradually not be needed anymore. In the context of the thesis we have successfully implemented the proposed model of context server and tested it with a context application, which operates in the principle of text classification of user entries in the search engines and its current location. The application of this data does not need to be captured manually, since they are automatically transmitted to the server when the new data appears

    The clinical relevance of off-label photodynamic therapy in onco-dermatology

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    BACKGROUND :Besides actinic keratosis, Bowen's disease, as well as superficial and small nodular basal cell carcinoma, aminolevulinic acid and methylaminolevulinic acid photodynamic therapy (ALA-PDT, MAL-PDT) present a broad potential of experimental indications in oncologic skin conditions. AIM :To present the various off-label indications with their respective PDT protocols, treatment results, level of evidence (A, B, C, D levels), and potential clinical interest. MATERIAL AND METHODS :A Pubmed search matched PDT with actinic cheilitis, anal, vulvar, and penile intraepithelial neoplasia (AIN, VIN, PIN), verrucous carcinoma, Paget disease, extramammary Paget disease, cutaneous B-cell lymphoma (CBCL), cutaneous T-cell lymphoma (CTCL), and cutaneous metastases of breast carcinoma. RESULTS :All indications presented interesting complete and partial cures, even in cases faling on previous standard treatments. All publications score C and D levels of evidence. The best PDT outcomes and the lowest recurrence rates concerned unifocal oncologic skin conditions with limited extension. Direct comparison of treatment data was difficult, as PDT protocols were highly variable. Comparative therapeutic trials vs standard care were rarely available. CONCLUSION :PDT represents a valuable treatment alternative in selected off-label oncologic skin conditions. However, literature data are too limited to support a hierarchic treatment position for PDT or a preferential protocol in these specific indications. There is a clear need for clinical trials evaluationg PDT vs standard treatments. In contrast to the approved PDT indications, where clinical evaluation accurately matches histologica evaluation, histology is required in these off- label indications to ensure treatment efficacy. Off-label use of PDT should be measured against the advantages and inconveniencies of standar treatment procedures.info:eu-repo/semantics/publishe

    Le crémage a du plomb dans l'aile.

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    Topical treatment is the cornerstone of therapy for patients suffering from psoriasis. Its efficacy and safety have been demonstrated in a large number of publications. However, in daily life, the treatment outcome is often less satisfactory than the results published in the literature. This phenomenon is clearly linked to non-adherence. Indeed, patients with psoriasis frequently consider the topical therapies frequently as a heavy burden. The successful management of psoriasis with topical agents requires a perfect understanding between the patient and the practionner, which provides regular renewal of the patient's motivation.English AbstractJournal Articleinfo:eu-repo/semantics/publishe
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