Cross reactive arrays of three-way junction sensors for steroid determination

This invention provides analyte sensitive oligonucleotide compositions for detecting and analyzing analytes in solution, including complex solutions using cross reactive arrays of analyte sensitive oligonucleotide compositions

Implicit-OR tiling of deoxyribozymes: Construction of molecular scale OR, NAND, and four-input logic gates

We recently reported the first complete set of molecular-scale logic gates based on deoxyribozymes. Here we report how we tile these logic gates and construct new logic elements: OR, NAND, and the first element with four inputs (i1^i5)Ú(i2^i6). Tiling of logic gates was achieved through a common substrate used for core deoxyribozyme; degradation of this substrate defines the output. This kind of connection between logic gates is an implicit-OR tiling, because it suffices that one componenet of the network is active for the whole network to give an output of 1