Small bowel perforation secondary to intestinal tuberculosis in patient with chronic idiopathic myelofibrosis

Idiopathic myelofibrosis is a clonal hematopoetic stem cell disorder due to a mutation in the signaling regulator gene Janus Kinase 2 (JAK2).The condition is widely treated with Ruxolitinib which is a JAK2 inhibitor along with prednisolone. However, these treatment despite promising has been linked with the risk of opportunistic infections and reactivation of tuberculosis.We reported a patient with chronic idiopathic myelofibrosis who developed small bowel perforations secondary to flare up of gut tuberculosis. The perforation sites were resected and double barrel stoma was created.peer-reviewe