Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology-2

<p><b>Copyright information:</b></p><p>Taken from "Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology"</p><p>http://www.biomedcentral.com/1472-6920/7/30</p><p>BMC Medical Education 2007;7():30-30.</p><p>Published online 5 Sep 2007</p><p>PMCID:PMC2045084.</p><p></p>ng endocrine physiology

Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology-5

<p><b>Copyright information:</b></p><p>Taken from "Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology"</p><p>http://www.biomedcentral.com/1472-6920/7/30</p><p>BMC Medical Education 2007;7():30-30.</p><p>Published online 5 Sep 2007</p><p>PMCID:PMC2045084.</p><p></p

Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology-1

<p><b>Copyright information:</b></p><p>Taken from "Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology"</p><p>http://www.biomedcentral.com/1472-6920/7/30</p><p>BMC Medical Education 2007;7():30-30.</p><p>Published online 5 Sep 2007</p><p>PMCID:PMC2045084.</p><p></p>hysiology

Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology-3

<p><b>Copyright information:</b></p><p>Taken from "Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology"</p><p>http://www.biomedcentral.com/1472-6920/7/30</p><p>BMC Medical Education 2007;7():30-30.</p><p>Published online 5 Sep 2007</p><p>PMCID:PMC2045084.</p><p></p>r systems taught only by didactic lectures

Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology-4

<p><b>Copyright information:</b></p><p>Taken from "Attitude of medical students towards Early Clinical Exposure in learning endocrine physiology"</p><p>http://www.biomedcentral.com/1472-6920/7/30</p><p>BMC Medical Education 2007;7():30-30.</p><p>Published online 5 Sep 2007</p><p>PMCID:PMC2045084.</p><p></p>t scale

Comprehensive Maturity Onset Diabetes of the Young (MODY) Gene Screening in Pregnant Women with Diabetes in India

<div><p>Pregnant women with diabetes may have underlying beta cell dysfunction due to mutations/rare variants in genes associated with Maturity Onset Diabetes of the Young (MODY). MODY gene screening would reveal those women genetically predisposed and previously unrecognized with a monogenic form of diabetes for further clinical management, family screening and genetic counselling. However, there are minimal data available on MODY gene variants in pregnant women with diabetes from India. In this study, utilizing the Next generation sequencing (NGS) based protocol fifty subjects were screened for variants in a panel of thirteen MODY genes. Of these subjects 18% (9/50) were positive for definite or likely pathogenic or uncertain MODY variants. The majority of these variants was identified in subjects with autosomal dominant family history, of whom five were in women with pre-GDM and four with overt-GDM. The identified variants included one patient with <i>HNF1A</i> Ser3Cys, two <i>PDX1</i> Glu224Lys, His94Gln, two <i>NEUROD1</i> Glu59Gln, Phe318Ser, one <i>INS</i> Gly44Arg, one <i>GCK</i>, <i>one ABCC8</i> Arg620Cys and one <i>BLK</i> Val418Met variants. In addition, three of the seven offspring screened were positive for the identified variant. These identified variants were further confirmed by Sanger sequencing. In conclusion, these findings in pregnant women with diabetes, imply that a proportion of GDM patients with autosomal dominant family history may have MODY. Further NGS based comprehensive studies with larger samples are required to confirm these finding</p></div

Additional file 1: of Evaluation of a training program of hypertension for accredited social health activists (ASHA) in rural India

Table S1. Description of Training Materials and Sessions. All downloadable from https://figshare.com/s/7bbfcc22e0c9c91a5ca03 DOI: https://doi.org/10.4225/03/5967f9a94970d . ASHA Training Manual. Table S2. Evaluation Materials and ASHA Resources. All downloadable from https://figshare.com/s/b94c7af22ae220540c45 DOI: https://doi.org/10.4225/03/5975a0f9da160 . (DOC 78 kb

Baseline characteristics of the study subjects.

<p>Baseline characteristics of the study subjects.</p

Detailed diagrammatic algorithm of the study with flow chart of NGS screening of the subject.

<p>Detailed diagrammatic algorithm of the study with flow chart of NGS screening of the subject.</p

Detailed pedigree charts of MODY positive pregnant women with diabetes.

<p>Detailed pedigree charts of MODY positive pregnant women with diabetes.</p