El desistimiento de la relación laboral y del cargo de manager público. WP CSDLE “Massimo D’Antona”.INT – 124/2015 = The withdrawal of the employment relationship and the Public manager position. WP CSDLE “Massimo D’Antona”.INT – 124/2015

No abstract

Trasferire lavoratori e attività: riflessioni e questioni a margine dell’implementazione del modello di governance della Città metropolitana = Transfer workers and activities: reflections and issues on the sidelines of the implementation of the metropolitan city governance model. WP C.S.D.L.E. “Massimo D’Antona”.IT – 279/2015

Transferring workers as a result of the processes of macro reorganization government is always a delicate time management full of worries and often fibrillation. The author tries to outline virtuous path applications for the mobility of staff in the PA since the new rules introduced by the reform Renzi-Madia (Law no. 214/2014). In particular, the attempt is to delineate their respective areas of competence attributed to the macro and micro organization as well as the protection and models of labor relations due under the aegis of each. The lesson gained in the private sector and consolidated around art. 2112 of the Civil Code, relating to transfers of company, offers, however, fruitful ideas for reflection as well in the public sector. Leaning against the background of protection consolidated in the private sector, just around the rules contained in this standard, you can open interpretive scenarios useful for the public sector. This especially with regard to issues raised as a result of the repeal of the Provinces and the transition to the new model of territorial governance of metropolitan Cities

Il polimorfismo delle dirigenze pubbliche e la “buona” amministrazione = The polymorphism of public managers and "good" administration. WP C.S.D.L.E. "Massimo D'Antona" .IT - 81/2008

N

La gestione della performance dei dirigenti pubblici: an, quando, quis e quomodo della “misurazione” e “valutazione” individuale = The management of public managers' performance: an, when, quis and quomodo of individual "measurement" and "evaluation". WP C.S.D.L.E. "Massimo D'Antona" .IT - 103/2010

No abstract

La nuova disciplina della somministrazione di lavoro tra poteri datoriali e diritti del lavoratore = The new discipline of the administration of work between employer powers and worker rights. WP C.S.D.L.E. "Massimo D'Antona" .IT - 33/2005

N

Il conflitto collettivo post moderno: lo “sciopero” dei lavoratori autonomi = The post-modern collective conflict: the "strike" of the self-employed. WP C.S.D.L.E. "Massimo D'Antona" .IT - 43/2006

N

The rapid spread of SARS-COV-2 Omicron variant in Italy reflected early through wastewater surveillance

The SARS-CoV-2 Omicron variant emerged in South Africa in November 2021, and has later been identified worldwide, raising serious concerns. A real-time RT-PCR assay was designed for the rapid screening of the Omicron variant, targeting characteristic mutations of the spike gene. The assay was used to test 737 sewage samples collected throughout Italy (19/21 Regions) between 11 November and 25 December 2021, with the aim of assessing the spread of the Omicron variant in the country. Positive samples were also tested with a real-time RT-PCR developed by the European Commission, Joint Research Centre (JRC), and through nested RT-PCR followed by Sanger sequencing. Overall, 115 samples tested positive for Omicron SARS-CoV-2 variant. The first occurrence was detected on 7 December, in Veneto, North Italy. Later on, the variant spread extremely fast in three weeks, with prevalence of positive wastewater samples rising from 1.0% (1/104 samples) in the week 5-11 December, to 17.5% (25/143 samples) in the week 12-18, to 65.9% (89/135 samples) in the week 19-25, in line with the increase in cases of infection with the Omicron variant observed during December in Italy. Similarly, the number of Regions/Autonomous Provinces in which the variant was detected increased from one in the first week, to 11 in the second, and to 17 in the last one. The presence of the Omicron variant was confirmed by the JRC real-time RT-PCR in 79.1% (91/115) of the positive samples, and by Sanger sequencing in 66% (64/97) of PCR amplicons. In conclusion, we designed an RT-qPCR assay capable to detect the Omicron variant, which can be successfully used for the purpose of wastewater-based epidemiology. We also described the history of the introduction and diffusion of the Omicron variant in the Italian population and territory, confirming the effectiveness of sewage monitoring as a powerful surveillance tool

La dirigenza pubblica responsabilizzata: modelli a confronto

Dottorato di ricerca in diritto del lavoro europeo . 11. ciclo. Tutore e coordinatore S. B. Caruso.Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome; Biblioteca Nazionale Centrale - P.za Cavalleggeri, 1, Florence / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Il datore di lavoro pubblico alla prova dell’emergenza Coronavirus. Il quadro normativo e la sua continua evoluzione. La disciplina semplificata del lavoro agile. Altre misure di gestione del personale nell’emergenza

analisi delle misure di gestione del personale adottate dalle pubbliche amministrazioni per fronteggiare la pandemi

Effects of Cerebrospinal Fluids from Alzheimer and Non-Alzheimer Patients on Neurons–Astrocytes–Microglia Co-Culture

Alzheimer’s disease (AD) is the most common form of dementia, characterized by the accumulation of β-amyloid plaques, tau tangles, neuroinflammation, and synaptic/neuronal loss, the latter being the strongest correlating factor with memory and cognitive impairment. Through an in vitro study on a neurons–astrocytes–microglia (NAM) co-culture system, we analyzed the effects of cerebrospinal fluid (CSF) samples from AD and non-AD patients (other neurodegenerative pathologies). Treatment with CSF from AD patients showed a loss of neurofilaments and spheroids, suggesting the presence of elements including CX3CL1 (soluble form), destabilizing the neurofilaments, cellular adhesion processes, and intercellular contacts. The NAM co-cultures were analyzed in immunofluorescence assays for several markers related to AD, such as through zymography, where the expression of proteolytic enzymes was quantified both in cell extracts and the co-cultures’ conditioned medium (CM). Through qRT-PCR assays, several genes involved in the formation of β-amyloid plaque, in phosphorylation of tau, and in inflammation pathways and MMP expression were investigated