'Death and Doctor Hornbook' by Robert Burns: A view from medical history

Robert Burns's poem, Death and Doctor Hornbook, 1785, tells of the drunken narrator's late night encounter with Death. The Grim Reaper is annoyed that ‘Dr Hornbook’, a local schoolteacher who has taken to selling medications and giving medical advice, is successfully thwarting his efforts to gather victims. The poet fears that the local gravedigger will be unemployed but Death reassures him that this will not be the case since Hornbook kills more than he cures. Previous commentators have regarded the poem as a simple satire on amateur doctoring. However, it is here argued that, if interpreted in the light of the exoteric and inclusive character of 18th century medical knowledge and practice, the poem is revealed to have a much broader reference as well as being more subtle and morally ambiguous. It is a satire on 18th century medicine as a whole

Making lawyers moral : Ethical codes and moral character

This article argues that professional codes of conduct cannot perform the important task of ensuring that lawyers uphold high ethical standards. Instead, moral behaviour by lawyers requires the development of fixed behavioural attributes relevant to legal practice - what may be called a lawyer's professional moral character. At the same time, however, along with other factors, professional codes are important in that they can either contribute to or detract from the successful development of professional moral character. If so, it is argued that in order to have the best chance of assisting the character development of lawyers, codes should neither take the form of highly detailed or extremely vague, aspirational norms, but should instead guide ethical decision-making by requiring them to consider a wide range of contextual factors when resolving ethical dilemmas

Community concepts in plant ecology: from Humboldtian plant geography to the superorganism and beyond

The paper seeks to provide an introduction to, and review of, the history of concepts of the plant community. Eighteenth-century naturalists recognised that vegetation was distributed geographically and that different species of plants and animals were interconnected in what would later be called ecological relationships. It was not, however, until the early nineteenth century that the study of vegetation became a distinctive and autonomous form of scientific inquiry. Humboldt was the first to call communities of plants ‘associations’. His programme for the empirical study of plant communities was extended by many European and North American botanists, throughout the nineteenth and into the twentieth century. There developed an almost complete consensus among ecologists that vegetation was made up of natural communities, discrete entities with real boundaries. However, there was little agreement about the nature of the putative unit or how it should be classified. Gleason advanced the alternative view that vegetation was an assemblage of individual plants with each species being distributed according to its own physiological requirements and competitive interactions. This debate was never wholly resolved and the divergent opinions can be discerned within early ecosystem theory

Salt intake and regulation in two passerine nectar drinkers: white-bellied sunbirds and New Holland honeyeaters

Avian nectarivores face the dilemma of having to conserve salts while consuming large volumes of a dilute, electrolyte-deficient diet. This study evaluates the responses to salt solutions and the regulation of salt intake in white-bellied sunbirds (Cinnyris talatala) and New Holland honeyeaters (Phylidonyris novaehollandiae). Birds were first offered a choice of four sucrose diets, containing no salt or 25, 50 or 75 mM NaCl. The experiment was repeated using five sucrose concentrations (0.075-0.63 M) as the base solution. Both species ingested similar amounts of all diets when fed the concentrated base solutions. However, when birds had to increase their intake to obtain enough energy on the dilute sucrose diets, there was a general avoidance of the higher salt concentrations. Through this diet switching, birds maintained constant intakes of both sucrose and sodium; the latter may contribute to absorption of their sugar diets. A second, no-choice experiment was designed to elucidate the renal concentrating abilities of these two nectarivores, by feeding them 0.63 M sucrose containing 5-200 mM NaCl over a 4-h trial. In both species, cloacal fluid osmolalities increased with diet NaCl concentration, but honeyeaters tended to retain ingested Na+, while sunbirds excreted it. Comparison of Na+ and K+ concentrations in ureteral urine and cloacal fluid showed that K+, but not Na+, was reabsorbed in the lower intestine of both species. The kidneys of sunbirds and honeyeaters, like those of hummingbirds, are well suited to diluting urine; however, they also appear to concentrate urine efficiently when necessary

The last great unknown? The impact of academic conferences.

What do academic conferences contribute? How do academic conferences make a difference both in the lives of academics and wider society? Donald Nicolson looks at a few examples of conferences that have been able to make a demonstrable impact and argues it is to the benefit of the academy to learn more about how to get the most out of these time-consuming events

Problematizing competence in clinical legal education : what do we mean by competence and how do we assess non-skill competencies?

The special issue of this journal is about problematizing assessment. However, in this article I want to start further back and problematize what is meant by competence. I think it is fair to say that when law clinicians speak about assessing competence they usually have in mind the assessment of skills. By contrast, I will argue that competence goes well beyond skills, at least if we understand skills in the narrow sense of technical legal skills, and includes in addition a values dimension. Moreover, if this dimension is added to the notion of skills, and clinical legal education (CLE) is expanded to include an understanding of how lawyers? skills are used, for whom and to what end, it might help reverse the traditional and still continuing antipathy in many law schools to CLE. For those like myself, who see law clinics as more about contributing to social justice than legal education (Nicolson 2006), the reluctance to embrace CLE is rooted (rightly or wrongly) in a political and moral stance. But for most academics, the antipathy - or, at best, apathy - towards CLE might be more to do with its association with skills training and the consequent assumption that it is unintellectual, unfit for the lofty heights of a liberal legal education and thus best left for the grubby business of preparing lawyers for practice (see eg Bradney 1995, 2003, Brownsword, 1999; Guth & Ashford, 2014)

Plato and Aristotle plan a symposium: a surreal take on academic conferences

Neatly summarising the insights first outlined in his earlier posts examining the merits of contemporary academic conferences, Donald Nicolson imagines a conversation between Plato and Aristotle as the two great thinkers make plans for their forthcoming symposium

Conference travel as a barrier to knowledge development

Following his previous post on the impact of academic conferences, Donald Nicolson considers the potential problems posed by conference travel. Are academics from the southern hemisphere and Asia disadvantaged by the disproportionate number of northern hemisphere venues? And might the realities of modern day international travel discourage some academics from attending conferences at all? Such barriers can impact on continuing professional development and the sharing of knowledge

Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells

Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses. MicroRNAs (miRNAs), small non-coding RNAs that regulate essential biological and cellular processes, have been found dysregulated in a wide range of tumours. The aim of this study was to identify miRNAs associated with ES. Differential expression of miRNAs was assessed in control equine fibroblasts (EqPalFs) and EqPalFs transformed with the BPV-1 genome (S6-2 cells). Using a commercially available miRNA microarray, 492 mature miRNAs were interrogated. In total, 206 mature miRNAs were differentially expressed in EqPalFs compared with S6-2 cells. Aberrant expression of these miRNAs in S6-2 cells can be attributed to the presence of BPV-1 genomes. Furthermore, we confirm the presence of 124 miRNAs previously computationally predicted in the horse. Our data supports the involvement of miRNAs in the pathogenesis of ES