Awakening response in offspring and partners.

<p>Cortisol Awakening Response (CAR). All three graphs present the mean cortisol level measured at the four time points. A) CAR in all offspring and partners. Analysis adjusted for age, gender, body mass index and current smoking habits. B) CAR in female offspring and partners. C) CAR in male offspring and partners. B,C) analysis adjusted for age, body mass index and current smoking habits. Data presented as means with the standard error of the mean (SEM). Statistical significance (p<0.05) denoted as an asterisk.</p

Salivary cortisol in offspring and partners.

<p>Means presented as mean salivary cortisol in nmol/L with 95% confidence internal.</p><p>Model 1: Crude; Model 2: Adjusted for age, gender, body mass index and current smoking; Model 3: Adjusted for age, gender, body mass index, current smoking and disease history (Type 2 Diabetes and Hypertension). All analyses were adjusted for familial relationship. Data presented as means with 95% confidence interval. Abbreviation; AUC_g Area Under the Curve with reference to the ground.</p

General characteristics of the study population.

<p>Age and body mass index are presented as means with the standard deviation. Abbreviation: COPD Chronic Obstructive Pulmonary Disease.</p

Salivary cortisol levels after overnight dexamethasone.

<p>Means presented as mean salivary cortisol in nmol/L with 95% confidence internal. Model 1: Crude; Model 2: Adjusted for age, gender, body mass index and current smoking; Model 3: Adjusted for age, gender, body mass index, current smoking and disease history (Type 2 Diabetes and Hypertension); Model 4: Adjusted for age, gender, body mass index, current smoking and disease history (Type 2 Diabetes and Hypertension) and salivary cortisol concentration at awakening on the first day. All analyses were adjusted for familial relationships. 1) Awakening salivary cortisol levels after overnight dexamethasone. 2) Difference between salivary cortisol level on awakening at day 0 and overnight dexamethasone.</p

Evening cortisol in offspring and partners.

<p>Evening cortisol. All three graphs present the mean cortisol level measured at the two time points. A) Evening cortisol in all offspring and partners. Analysis adjusted for age, gender, body mass index and current smoking habits. B) Evening cortisol in female offspring and partners. C) Evening cortisol in male offspring and partners. B,C) analysis adjusted for age, body mass index and current smoking habits. Data presented as means with the standard error of the mean (SEM). Statistical significance (p<0.05) denoted as an asterisk.</p