WILL FARMERS USE SAFER PESTICIDES?

Virtually all technology adoption studies are conducted ex post, yet policy makers often need to assess the likely level of adoption before the technology is introduced. This study uses data from a contingent valuation survey of Michigan corn growers to assess what factors would influence the adoption of two safer corn herbicides, one that is not carcinogenic and one that does not leach. Results indicate that price, risk perception, and sources of pest control information are all important. This suggests that public policies designed to change perceptions and improve information dissemination may encourage voluntary use of more environmentally friendly technologies.atrazine, cancer risk, contingent valuation, herbicides, nitrate leaching, public policy, technology adoption, Crop Production/Industries,

The Marketing Performance of Illinois and Kansas Wheat Farmers

The purpose of this paper is to analyze the marketing performance of wheat farmers in Illinois and Kansas over 1982–2004. The results show that farmer benchmark prices for wheat in Illinois and Kansas fall in the middle third of the price range about half to three-quarters of the time. Consistent with previous studies, this refutes the contention that Illinois and Kansas wheat farmers routinely market the bulk of their wheat crop in the bottom portion of the price range. Tests of the average difference between farmer and market benchmark prices are sensitive to the market benchmark considered. The marketing performance of wheat farmers in Illinois and Kansas is about equal to the market if a 24- or 20-month market benchmark is used, slightly above the market if a 12-month price benchmark is used, and significantly less than the market if the harvest benchmark is used. The sensitivity of marketing performance to the market benchmark considered is explained by the seasonal pattern of prices. While Illinois producers performed slightly better than their counterparts in Kansas, notable differences in performance across these two geographic areas is not observed.benchmarks, Illinois, Kansas, marketing, performance, price, wheat, Agribusiness, Crop Production/Industries, Marketing, Production Economics, Productivity Analysis, Q11, Q13,

Inferring Biological Population Membership: An Exploration of the Continuum of Genetic Relationships.

To easily collect samples in a genetic study, we use proxies for membership in biological populations. This means we are often placing or assigning individuals on the basis of operational designations - closer relationships being family, while distant relationships being population membership or even more distant relationships- being ancestrally related population relationships. While there is a correlation between genetic variation and the operational designation placed on individuals, the designation does not necessarily define the genetic relationship. Genetic relationships exist in a continuum and mapping the relationships among sample members from the proxy to the genetics is not straightforward. My dissertation examines the genetic relationships from two scales: between individuals in a population and between ancestrally related populations. I first develop a method to examine population membership using just two individuals. The homogeneity method is a statistical test of the null hypothesis that two individuals are unrelated members of the same randomly mating population. This test requires that the pair of individuals be genotyped for a battery of genetic markers, but it does not require information about the pair of individuals or the populations that they might belong to. Potential applications of this test include 1) identifying population stratification in biomedical samples, 2) solving forensic cases from molecular evidence, 3) management of endangered species, and 4) examining human population history. To examine relationships between populations, I investigate the effect of ancestral population relationships on methods designed to assess population structure. I develop a novel method to simulate multiple SNP genotypes from different populations. This method simulates realistic allele frequencies and captures the shared ancestry of populations so that the user can efficiently choose SNPs with a flexible ascertainment. I then simulate individuals from populations representing a divergent and less divergent phylogenetic tree. I use the simulated data in GHM (generalized hierarchical modeling) and STRUCTURE (Bayesian k-means clustering) to compare the true underlying ancestry. In summary, my dissertation research provides novel quantitative tools and analyses that aid in understanding the genetics of biological populations.Ph.D.Human GeneticsUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/78959/1/nmscott_1.pd

An Interprofessional Consensus of Core Competencies for Prelicensure Education in Pain Management: Curriculum Application for Physical Therapy

Core competencies in pain management for prelicensure health professional education were recently established. These competencies represent the expectation of minimal capabilities for graduating health care students for pain management and include 4 domains: multidimensional nature of pain, pain assessment and measurement, management of pain, and context of pain (Appendix 1). The purpose of this article is to advocate for and identify how core competencies for pain can be applied to the professional (entry-level) physical therapist curriculum. By ensuring that core competencies in pain management are embedded within the foundation of physical therapist education, physical therapists will have the core knowledge necessary for offering best care for patients, and the profession of physical therapy will continue to stand with all health professions engaged in comprehensive pain management

Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process.

To understand the impact of epigenetics on human misfolding disease, we apply Gaussian-process regression (GPR) based machine learning (ML) (GPR-ML) through variation spatial profiling (VSP). VSP generates population-based matrices describing the spatial covariance (SCV) relationships that link genetic diversity to fitness of the individual in response to histone deacetylases inhibitors (HDACi). Niemann-Pick C1 (NPC1) is a Mendelian disorder caused by >300 variants in the NPC1 gene that disrupt cholesterol homeostasis leading to the rapid onset and progression of neurodegenerative disease. We determine the sequence-to-function-to-structure relationships of the NPC1 polypeptide fold required for membrane trafficking and generation of a tunnel that mediates cholesterol flux in late endosomal/lysosomal (LE/Ly) compartments. HDACi treatment reveals unanticipated epigenomic plasticity in SCV relationships that restore NPC1 functionality. GPR-ML based matrices capture the epigenetic processes impacting information flow through central dogma, providing a framework for quantifying the effect of the environment on the healthspan of the individual

The ties that bind: Knowledge-seeking networks and auditor job performance

The dissemination of knowledge in audit firms is a critical process that has gone relatively unexamined by researchers. Using social network analysis to quantify the knowledge-seeking networks in a Big 4 audit firm in the U.S., we examine the association between the types and patterns of knowledge-seeking ties and individual auditor performance. Our initial finding is that auditor job performance is negatively associated with the number of knowledge-seeking ties. Further, our analyses demonstrate that this negative association is being driven by explicit knowledge-seeking rather than tacit knowledge-seeking activities and is stronger for higher-ranked auditors. Thus, knowledge-seeking by auditors may come at a cost, particularly when that knowledge is codifiable and when the seeking is done by those at higher levels of the firm. In a post-hoc analysis, we find that tacit knowledge-seeking ties to managers can be beneficial for auditor performance, and tacit knowledge-seeking ties to senior managers and partners is sometimes detrimental. In sum, this suggests that who is seeking knowledge and who is being sought for knowledge are both important for performance. Our findings may assist researchers to better understand how auditors leverage their social connections to learn, which in turn may affect audit efficiency and effectiveness. Further, audit firms might benefit from better understanding the consequences of knowledge-seeking from different sources and use this understanding to make decisions that maximize desirable information flows

Complex Total Ankle Arthroplasty.

Total ankle arthroplasty is a viable surgical technique for the treatment of end-stage degenerative joint disease. With continued advancement in prosthetic design, refined surgical techniques, and improved outcomes, the indications for total ankle replacement have expanded to include cases of increasing complexity. With meticulous preoperative planning and exacting execution, many frontal plane deformities and cases of avascular necrosis can now be successfully addressed at the time of prosthesis implantation or in a staged procedure

The Use of Decellularized Human Placenta in Full-Thickness Wound Repair and Periarticular Soft Tissue Reconstruction: An Update on Regenerative Healing.

Prolonged or incomplete healing of the foot and ankle can pose significant challenges. Therefore, investigators have begun searching for alternative treatment strategies. With advances in tissue engineering, decellularized human placental connective tissue matrix has been suggested as a means to achieve more rapid and complete healing for various soft tissue and bone procedures. Basic science and clinical studies have shown that decellularized human placental connective tissue matrix can support regenerative healing through cellular migration, accelerated tissue remodeling, and the establishment of functional tissue. Additional research is needed to fully explore and evaluate clinical applications within the foot and ankle

Dr. Mary Edwards Walker: years ahead of her time.

Women phsycians in the United States were virtually nonexistent in the early to mid-1800s. Traditional medical schools still did not accept women, and few secretarian or eclectic medical schools were beginning to open their doors to female students. In 1849 at Geneva College, Elizabeth Blackwell became the first woman to achieve a medical degree in the United States.1 At the time of the Civil War, the few women who had managed to obtain medical degrees mainly served as nurses in the war, because society was not yet ready to accept the female physician.2 Dr. Mary Edwards Walker would help change the role of women physicians, becoming not only a valuable surgeon for the Union Army, but also a catalyst for the introduction and advancement of women in medicine