1,098 research outputs found
Strategic planning in public transport
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1995.Includes bibliographical references (leaves 188-191).by Lucy Nicola Shaw.M.S
Studies of dye sensitised photovoltaic cells
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN029715 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm
Networks of interacting co-regulated genes distinguish the inner cell mass (ICM) from the
differentiated trophectoderm (TE) in the preimplantation blastocyst, in a species specific manner. In mouse the ground state pluripotency of the ICM appears to be maintained in murine embryonic stem cells (ESCs) derived from the ICM. This is not the case for human ESCs. In order to gain insight into this phenomenon, we have used quantitative network analysis to identify how similar human (h)ESCs are to the human ICM. Using the hESC lines MAN1, HUES3 and HUES7 we have shown that all have only a limited overlap with ICM specific gene expression, but that this overlap is enriched for network
properties that correspond to key aspects of function including transcription factor activity and the hierarchy of network modules. These analyses provide an important framework which highlights the developmental origins of hESCs
Modification of cleaning product formulations could improve indoor air quality
Cleaning products contain numerous individual chemicals, which can be liberated on use. These species can react in air to form new chemical species, some of which are harmful to health. This paper uses a detailed chemical model for indoor air chemistry, to understand the chemical reactions that can occur following cleaning, assuming cleaning products with different proportions of limonene, αâpinene, and ÎČâpinene are used. The tests included the pure compounds, 50:50 mixtures and mixtures in proportion to the rates of reaction with ozone and the hydroxyl radical. For the 3 h following cleaning, pure αâpinene was most efficient at producing particles, pure limonene for nitrated organic material, and a 50:50 mixture of ÎČâpinene and limonene for formaldehyde, leading to enhancements of 1.1 Όg/m(3), 400 ppt, and 1.8 ppb, respectively, compared to no cleaning. Cleaning in the afternoon enhanced concentrations of secondary pollutants for all the mixtures, owing to higher outdoor and hence indoor ozone compared to the morning. These enhancements in concentrations lasted several hours, despite the cleaning emissions only lasting for 10 min. Doubling the air exchange rate enhanced concentrations of formaldehyde and particulate matter by ~15% while reducing that of nitrated organic material by 13%. Changing product formulations has the potential to change the resulting indoor air quality and consequently, impacts on health
INCHEM-Py : An open source Python box model for indoor air chemistry
The INdoor CHEMical model in Python (INCHEM-Py) is an open source box model that creates and solves a system of coupled Ordinary Differential Equations (ODEs) to provide predicted concentrations of indoor air pollutants through time. It is a refactor of the indoor detailed chemical model originally developed by Carslaw (20017) with improvements in form, function, and accessibility.
INCHEM-Py takes the Master Chemical Mechanism (MCM), a near explicit mechanism developed for atmospheric chemistry, and additional chemical mechanisms that have been developed specifically for indoor air. These include gas-to-particle partitioning for three of the commonly encountered terpenes indoors (limonene and alpha- and beta-pinene), improved photolysis parametrisation, indoor-outdoor air exchange, and deposition to surfaces.
Typical usage of INCHEM-Py is either alongside experiment, where it can be used to gain a deeper insight into the chemistry through its ability to track a vast array of species concentrations or as a stand-alone method of investigating chemical events that occur indoors over a range of conditions. INCHEM-Py is open source, has no black box processes, and all inputs can be tracked through the model allowing for complete understanding of the system.
A wide array of outputs from the model can be accessed, including species concentrations, species reactivity and production rates, photolysis values, and summations such as the total peroxy radical concentration. Custom reactions and summations can also be added by users to tailor the model to specific indoor scenarios.
A full pdf manual is included within this repository, including a quick start guide, this README is not intended to cover every aspect of INCHEM-Py but should be sufficient for users to get started.
A copy of the GNU General Public License v3.0 under which this project is licenced is included in this repository.This work is funded by a grant from the Alfred P. Sloan Foundation, grant number 2018-10083. Conclusions reached or positions taken by researchers or other grantees represent the views of the grantees themselves and not those of the Alfred P. Sloan Foundation or its trustees, officers, or staff
Understanding the use of geographical information systems (GIS) in health informatics research: A review
Background: The purpose of this literature review is to understand geographical information systems (GIS) and how they can be applied to public health informatics, medical informatics, and epidemiology.Method: Relevant papers that reflected the use of geographical information systems (GIS) in health research were identified from four academic databases: Academic Search Complete, BioMed Central, PubMed Central, and Scholars Portal, as well as Google Scholar. The search strategy used was to identify articles with âgeographic information systemsâ, âGISâ, âpublic healthâ, âmedical informaticsâ, âepidemiologyâ, and âhealth geographyâ as main subject headings or text words in titles and abstracts. Papers published between 1997 and 2014 were considered and a total of 39 articles were included to inform the authors on the use of GIS technologies in health informatics research.Results: The main applications of GIS in health informatics and epidemiology include disease surveillance, health risk analysis, health access and planning, and community health profiling. GIS technologies can significantly improve quality and efficiency in health research as substantial connections can be made between a populationâs health and their geographical location.Conclusions: Gains in health informatics can be made when GIS are applied through research, however, improvements need to occur in the quantity and quality of data input for these systems to ensure better geographical health maps are used so that proper conclusions between public health and environmental factors may be made
Uranyl to Uranium(IV) Conversion through Manipulation of Axial and Equatorial Ligands
The controlled manipulation of the axial oxo and equatorial halide ligands in the uranyl dipyrrin complex, UO2Cl(L), allows the uranyl reduction potential to be shifted by 1.53 V into the range accessible to naturally occurring reductants that are present during uranium remediation and storage processes. Abstraction of the equatorial halide ligand to form the uranyl cation causes a 780 mV positive shift in the UV/UIV reduction potential. Borane functionalization of the axial oxo groups causes the spontaneous homolysis of the equatorial UâCl bond and a further 750 mV shift of this potential. The combined effect of chloride loss and borane coordination to the oxo groups allows reduction of UVI to UIV by H2 or other very mild reductants such as Cp*2Fe. The reduction with H2 is accompanied by a BâC bond cleavage process in the oxo-coordinated borane
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Male New Zealand robins (Petroica longipes) cater to their mate's desire when sharing food in the wild.
In many species that have bi-parental care, food-sharing males provide vital nutritional resources to their mates during reproduction. However, it is currently unknown whether females can signal specific desires to their mates, or if males can cater to female desire in the wild. Here we investigate whether and how wild male North Island robins (Petroica longipes) respond to changes in their mates' desires and nutritional need when sharing food. We demonstrate that wild female robins' desire for particular foods changes over short time periods; when given the choice between two types of insect larvae, females prefer the type they have not recently eaten. In our experiments, wild male robins preferentially shared the larvae type that their mate was most likely to desire and also increased the quantity of food shared if she had begun incubating. Males catered to their mates' desire when female behaviour was the only cue available to guide their choices. This is the first evidence that females may behaviourally communicate their specific food desires to their mates, enabling males to cater to fine-scale changes in their mates' nutritional requirements in the wild. Such a simple behaviour-reading mechanism has the potential to be widespread among other food-sharing species
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